5a-Pregnane-3,20-dione (Synonyms: 5α-DHP, NSC 18319, 5α-Pregnanedione) |
| Catalog No.GC32410 |
A progesterone receptor agonist and progesterone metabolite
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 566-65-4
Sample solution is provided at 25 µL, 10mM.
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5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.
5a-Pregnane-3,20-dione decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerizes F-actin in MCF-7 breast cancer cells[1].
[1]. Wiebe JP, et al. The endogenous progesterone metabolite, 5a-pregnane-3,20-dione, decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerized F-actin in MCF-7 breast cancer cells. Endocrine. 2001 Oct;16(1):7-14.
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