(Ala1)-PAR4 (1-6) (mouse) (trifluoroacetate salt) (Synonyms: H-Ala-Tyr-Pro-Gly-Lys-Phe-OH, AYPGKF) |
| Catalog No.GC41696 |
(Ala1)-PAR4 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 4 (PAR4) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse PAR4 and residues 60-65 of the full-length sequence with an alanine residue substituted for glycine at position 1/60.
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Sample solution is provided at 25 µL, 10mM.
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(Ala1)-PAR4 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 4 (PAR4) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse PAR4 and residues 60-65 of the full-length sequence with an alanine residue substituted for glycine at position 1/60. It is 10-fold more potent than PAR4 (1-6) , triggering [3H]inositol phosphate release from KOLF cells expressing human PAR4 at levels comparable to 30 nM thrombin when used at a concentration of 500 μM. (Ala1)-PAR4 (1-6) induces aggregation of human platelets.
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