| Aldosterone Catalog No.GC41390 |
Sample solution is provided at 25 µL, 10mM.
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| Cas No. | 52-39-1 | SDF | Download SDF |
| Synonyms | 18-Aldocorticosterone, NSC 73856, Reichstein X | ||
| Chemical Name | 11β,21-dihydroxy-3,20-dioxo-pregn-4-en-18-al | ||
| Canonical SMILES | O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C([H])=O)[C@@]3([H])CC[C@@H]4C(CO)=O)=C1 | ||
| Formula | C21H28O5 | M.Wt | 360.4 |
| Solubility | 30mg/mL in DMSO, ethanol, DMF | Storage | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. | ||
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
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Aldosterone is a steroid hormone secreted by the adrenal cortex and is the principle mineralocorticoid controlling sodium and potassium balance.[1],[2] Its primary role is to promote unidirectional salt reabsorption in epithelial tissues. Aldosterone is synthesized from cholesterol in the zona glomerulosa of the adrenal cortex and its secretion is regulated via the renin-angiotensin system.[3]
Reference:
[1]. Agarwal, M.K., and Mirshahi, M. General overview of mineralocorticoid hormone action. Pharmacology & Toxicology 84, 273-326 (1999).
[2]. Rogerson, F.M., and Fuller, P.J. Mineralocorticoid action. Steroids 65, 61-73 (2000).
[3]. Lumbers, E.R. Angiotensin and aldosterone. Regulatory Peptides 80, 91-100 (1999).