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Artemisone

Catalog No.GC34475

Artemisone (Artemifone) is a potent and semi-synthetic antimalarial, inhibits P.

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Artemisone Chemical Structure

Cas No.: 255730-18-8

Size Price Stock Qty
10mM (in 1mL DMSO)
$357.00
In stock
5mg
$324.00
In stock
10mg
$510.00
In stock
50mg
$1,530.00
In stock
100mg
$2,457.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Artemisone (Artemifone) is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains, with a mean IC50 of 0.83 nM[1]. IC50: 0.83 nM (P. falciparum)[1]

Artemisone inhibits 3D7 and K1 P. falciparum, with IC50s of 0.88±0.59 and 1.23±0.64 nM, respectively[1].

Artemisone is effectve at inhibiting the parasitaemia in the P. berghei NY susceptible strain, with an ED50 of 9.62 mg/kg via subcutaneous route and 11.67 mg/kg via oral administration[1].Artemisone (3, 1, 0.3 and 0.1 mg/kg, s.c.) in combination with ohter antimalarials has enhanced effect against the chloroquine-resistant line P. yoelii NS[1]

[1]. Vivas L, et al. Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo. J Antimicrob Chemother. 2007 Apr;59(4):658-65.

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Average Rating: 5 ★★★★★ (Based on Reviews and 34 reference(s) in Google Scholar.)

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