AZD5904 |
| Catalog No.GC30783 |
AZD5904 is a selective and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM and has similar potency in mouse and rat.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 618913-30-7
Sample solution is provided at 25 µL, 10mM.
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AZD5904 is a potent and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM and has similar potency in mouse and rat.
AZD5904 is a potent and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM and has similar potency in mouse and rat. It is 10 to 19-fold selective compare to the closely related lactoperoxidase and thyroid peroxidase; >70-fold to a broad panel of other enzymes, ion channels, and receptors. In isolated human neutrophils, 1 µM AZD5904 inhibits PMA stimulated HOCl by >90%[1].
[1]. Myeloperoxidase (MPO) inhibitor.
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
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