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B-Raf IN 1 (Synonyms: B-RAF Inhibitor 1)

Catalog No.GC10534

B-Raf inhibitor

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B-Raf IN 1 Chemical Structure

Cas No.: 950736-05-7

Size Price Stock Qty
1mg
$190.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

B-Raf IN 1 is a potent and selective B-Raf kinase inhibitor with an IC50 of 24 nM.

B-Raf IN 1 (Compound 10n) inhibits WM 266-4 and HT29 cells with IC50s of 0.92 and 0.78 μM, respectively[1].

References:
[1]. Berger DM, et al. Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6519-23.

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