Beauvericin |
| Catalog No.GC17342 |
antibacterial and antifungal activities
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 26048-05-5
Sample solution is provided at 25 µL, 10mM.
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Beauvericin is a mycotoxin originally derived from B. bassiana, a common fungal parasite of arthropods. It is also produced by the fungus Fusarium, a pathogen of insects and plants.[1] Beauvericin is cytotoxic against insect cells, killing the insect cell line SF-9 with a 50% cytotoxic concentration of 2.5 μM.[2] In mammalian cells, beauvericin induces apoptosis with an IC50 value of 4.5 μM.[1],[3]
Reference:
[1]. Logrieco, A., Moretti, A., Castella, G., et al. Beauvericin production by Fusarium species. Applied and Environmental Microbiology 64(8), 3084-3088 (1998).
[2]. Calo, L., Fornelli, F., Nenna, S., et al. Beauvericin cytotoxicity to the invertebrate cell line SF-9. J.Appl.Genet. 44(4), 515-520 (2003).
[3]. Tonshin, A.A., Teplova, V.V., Andersson, M.A., et al. The Fusarium mycotoxins enniatins and beauvericin cause mitochondrial dysfunction by affecting the mitochondrial volume regulation, oxidative phosphorylation and ion homeostasis. Toxicology 276, 49-57 (2010).
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