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CAY10509

Catalog No.GC18898

The actions of many clinical prostaglandins, including those used for estrous synchronization and for reduction of intraocular pressure, are mediated through the FP receptor.

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CAY10509 Chemical Structure

Cas No.: 1245699-47-1

Size Price Stock Qty
500μg
$108.00
In stock
100μg
$33.00
In stock
1mg
$197.00
In stock
5mg
$816.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

The actions of many clinical prostaglandins, including those used for estrous synchronization and for reduction of intraocular pressure, are mediated through the FP receptor. CAY10509 is an analog of PGF2α containing a thio-fluorobenzene substituent in the lower side chain. CAY10509 has an IC50 of about 30 nM when tested for binding to the recombinant human FP receptor.

Chemical Properties

Cas No. 1245699-47-1 SDF
Chemical Name 9α,11α,15R-trihydroxy-17-thiofluorophenoxy-17,18,19,20-tetranor-prostan-1-oic acid, methyl ester
Canonical SMILES O[C@@H]1C[C@H](O)[C@H](CCCCCCC(OC)=O)[C@H]1CC[C@@H](O)CSC2=C(F)C=CC=C2
Formula C23H35FO5S M.Wt 442.6
Solubility DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 100 mg/ml,PBS (pH 7.2): 0.25 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 2.2594 mL 11.2969 mL 22.5938 mL
5 mM 0.4519 mL 2.2594 mL 4.5188 mL
10 mM 0.2259 mL 1.1297 mL 2.2594 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Reviews

Review for CAY10509

Average Rating: 5 ★★★★★ (Based on Reviews and 35 reference(s) in Google Scholar.)

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