CAY10578 |
| Catalog No.GC43177 |
Casein Kinase 2 (CK2) is a constitutive protein kinase involved in many signal transduction pathways.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 19231-60-8
Sample solution is provided at 25 µL, 10mM.
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Casein Kinase 2 (CK2) is a constitutive protein kinase involved in many signal transduction pathways. CK2 is known to negatively regulate apoptosis, and its activity is increased in many proliferating tissues and tumors, which lends promise as an anticancer drug target. CAY10578 is a potent inhibitor of CK2 with an IC50 value of 0.3 µM. This compound is ATP competitive, displaying a Ki value of 0.2 µM and only minimally inhibits the activities of other protein kinases (e.g., GSK3, Cdk5, and MSK1).
Average Rating: 5 (Based on Reviews and 35 reference(s) in Google Scholar.)
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