CP 24,879 (hydrochloride) (Synonyms: p(Isopentyloxy)aniline) |
| Catalog No.GC43319 |
Essential fatty acid deficiency symptoms include immune system depression and a general state of inflammatory inhibition.
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Cas No.: 10141-51-2
Sample solution is provided at 25 µL, 10mM.
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Essential fatty acid deficiency symptoms include immune system depression and a general state of inflammatory inhibition. CP 24,879 is an inhibitor of arachidonic acid biosynthesis acting via the inhibition of δ5/δ6 desaturase. Mice injected with CP 24,879 at 3 mg/kg had a reduction of liver arachidonate content of approximately 50%. Murine mastocytoma cells treated with 5 µM CP 24,879 showed increased mead acid content and nearly complete ablation of leukotriene C4 synthesis, consistent with a desaturase inhibition-induced state of essential fatty acid deficiency.
Average Rating: 5 (Based on Reviews and 31 reference(s) in Google Scholar.)
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