|DEA NONOate Catalog No.GC18447|
Sample solution is provided at 25 µL, 10mM.
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|Cas No.||372965-00-9||SDF||Download SDF|
|Chemical Name||Diethylammonium (Z)-1-(N,N-diethylamino)diazen-1-ium-1,2-diolate|
|Solubility||25mg/mL in ethanol, 2mg/mL in DMSO & DMF||Storage||Store at -80°C|
|General tips||For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.|
|Shipping Condition||Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
DEA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 2 minutes and 16 minutes at 37°C and 22-25°C, pH 7.4, respectively, to liberate 1.5 moles of NO per mole of parent compound.
. Maragos, C.M., Morley, D., Wink, D.A., et al. Complexes of ∙NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects. Journal of Medicinal Chemistry 34, 3242-3247 (1991).
. Keefer, L.K., Nims, R.W., Davies, K.M., et al. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms. Methods in Enzymology 268, 281-293 (1996).