Home>>DEA NONOate
DEA NONOate Catalog No.GC18447

Size Price Stock Qty
10mg
$23.00
In stock
50mg
$62.00
In stock
100mg
$114.00
In stock
500mg
$514.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Quality Control

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Chemical Properties

Cas No. 372965-00-9 SDF Download SDF
Synonyms Diethylamine NONOate,DEA/NO
Chemical Name Diethylammonium (Z)-1-(N,N-diethylamino)diazen-1-ium-1,2-diolate
Canonical SMILES CCN(N([O-])N=O)CC.CC[NH2+]CC
Formula C4H11N3O2.C4H11N M.Wt 206.3
Solubility 25mg/mL in ethanol, 2mg/mL in DMSO & DMF Storage Store at -80°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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Background

DEA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 2 minutes and 16 minutes at 37°C and 22-25°C, pH 7.4, respectively, to liberate 1.5 moles of NO per mole of parent compound.[1][2]

Reference:
[1]. Maragos, C.M., Morley, D., Wink, D.A., et al. Complexes of ∙NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects. Journal of Medicinal Chemistry 34, 3242-3247 (1991).
[2]. Keefer, L.K., Nims, R.W., Davies, K.M., et al. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms. Methods in Enzymology 268, 281-293 (1996).