EX-527 S-enantiomer |
| Catalog No.GC13417 |
EX-527 S-enantiomer ((S)-EX-527) is a potent and selective SIRT1 inhibitor, with an IC50 of 98 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 848193-68-0
Sample solution is provided at 25 µL, 10mM.
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Selisistat S-enantiomer (EX-527 S-enantiomer) is the S-enantiomer of Selisistat, with an IC50 of 123 nM for SIRT1. Selisistat S-enantiomer is much more potent than Selisistat R-enantiomer.
References:
[1]. Napper AD, et al. Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. J Med Chem. 2005 Dec 15;48(25):8045-54.
Average Rating: 5 (Based on Reviews and 35 reference(s) in Google Scholar.)
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