Ferrous bisglycinate (Synonyms: Ferric glycinate) |
| Catalog No.GC60838 |
An iron amino acid chelate
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 20150-34-9
Sample solution is provided at 25 µL, 10mM.
Ferrous bisglycinate is an orally active iron fortificants and therapeutic iron supplements. Ferrous bisglycinate can be used for the research of iron deficiency anemia[1][2].
Ferrous bisglycinate (25-200 μM; 2 h) does not affect the Caco-2 cells viability[2].Ferrous bisglycinate (25 μM; 2 h) increases ferritin content in the Caco-2 cells[2]. Cell Viability Assay[2] Cell Line: Caco-2 cells
Ferrous bisglycinate (500 mg/kg iron; p.o.) exerts a protective effect on colitis in mice[3]. Animal Model: Female C57BL/6 mice are induced colitis by dextran sodium sulfate (DSS)[3]
References:
[1]. Ferrari P, et, al. Treatment of mild non-chemotherapy-induced iron deficiency anemia in cancer patients: comparison between oral ferrous bisglycinate chelate and ferrous sulfate. Biomed Pharmacother. 2012 Sep; 66(6): 414-8.
[2]. Yu X, et, al. Iron Transport from Ferrous Bisglycinate and Ferrous Sulfate in DMT1-Knockout Human Intestinal Caco-2 Cells. Nutrients. 2019 Feb 26; 11(3): 485.
[3]. Constante M, et, al. Iron Supplements Modulate Colon Microbiota Composition and Potentiate the Protective Effects of Probiotics in Dextran Sodium Sulfate-induced Colitis. Inflamm Bowel Dis. 2017 May; 23(5): 753-766.
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