Hydroxyethyl cellulose (2-Hydroxyethyl cellulose) |
Catalog No.GC30153 |
Hydroxyethyl cellulose (2-Hydroxyethyl cellulose) is a non-ionic, modified cellulose polymer used as a thickening agent for aqueous cosmetic and personal care formulations.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 9004-62-0
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Hydroxyethyl cellulose is a non-ionic, water soluble, modified cellulose polymer used as a thickening agent for aqueous cosmetic and personal care formulations.
Stabilization of graphene oxide in physiological solution is performed using hydroxyethyl cellulose to make the resultant nanohybrid suitable for targeted drug delivery purposes. Hydroxyethyl cellulose effectively stabilizes graphene oxid in electrolyte solutions and the mechanism of stabilization appears to be depended on hydroxyethyl cellulose content. Hydroxyethyl cellulose content in the nanohybrid plays an important role in final application to make it applicable either as a carrier for controllable drug release or as a folate-targeted drug carrier[1]. Hydroxyethyl cellulose shows superior cryoprotective effects on LDH during freeze thawing, and considerable lyoprotective effects during the freeze drying process. Annealing has limited influence on the stabilizing effect of hydroxyethyl cellulose. The extensive reconstitution times of the hydroxyethyl cellulose lyophilisates could be greatly improved by incorporation of the surfactant Tween 80 into the formulations prior to freeze drying[2].
[1]. Mianehrow H, et al. Graphene-oxide stabilization in electrolyte solutions using hydroxyethyl cellulose for drug delivery application. Int J Pharm. 2015 Apr 30;484(1-2):276-82. [2]. Al-Hussein A, et al. Investigation of the stabilizing effects of hydroxyethyl cellulose on LDH during freeze drying and freeze thawing cycles. Pharm Dev Technol. 2015 Jan;20(1):50-9.
Cas No. | 9004-62-0 | SDF | |
Canonical SMILES | [Cellulose glycol] | ||
Formula | M.Wt | ||
Solubility | Water : 9.09 mg/mL (warming and heat to 93°C);DMSO : < 1 mg/mL (insoluble or slightly soluble) | Storage | Store at -20°C |
General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Average Rating: 5
(Based on Reviews and 29 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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