Lenampicillin hydrochloride (KBT 1585 hydrochloride) |
| Catalog No.GC34147 |
Lenampicillin hydrochloride (KBT 1585 hydrochloride) (KBT 1585 hydrochloride) is an orally active prodrug of Ampicillin and is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins (transpeptidase). Lenampicillin hydrochloride (KBT 1585 hydrochloride) has improved absorption and decreased side effects compares to Ampicillin and is applied in the investigation of the suppurative skin and soft tissue infection .
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 80734-02-7
Sample solution is provided at 25 µL, 10mM.
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Lenampicillin (hydrochloride) is the efficient prodrug of ampicillin (ABPC ) in terms of the enhancement of absorption and decrease of side effects.In vivo : The intestinal absorption of LAPC is satisfactory in view of the urinary excretion of metabolites, accounting for 93% of dose in human, 74% in dogs and 55% in rats, respectively.
[1]. Awata N et al. [Metabolism of lenampicillin hydrochloride. II. Metabolism of promoiety]. Jpn J Antibiot. 1985 Jul;38(7):1785-93. [2]. Awata N et al. [Metabolism of lenampicillin hydrochloride. I. Metabolism of ampicillin structure]. Jpn J Antibiot. 1985 Jul;38(7):1776-84.
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