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MPP+ Iodide Catalog No.GC18188

An active metabolite of MPTP

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Sample solution is provided at 25 µL, 10mM.

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Chemical Properties

Cas No. 36913-39-0 SDF Download SDF
Synonyms N/A
Chemical Name 1-methyl-4-phenyl-pyridinium, monoiodide
Canonical SMILES C[N+](C=C1)=CC=C1C2=CC=CC=C2.[I-]
Formula C12H12N.I M.Wt 297.1
Solubility 100 mM in Water Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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MPP+ is an active metabolite of MPTP , a neurotoxin used to cause selective destruction of dopaminergic neurons in animal models of parkinsonism. MPP+ induces neurotoxicity primarily by inhibiting complex I of the mitochondrial electron transport chain, resulting in ATP depletion and increased oxidative stress. The key features of different neurotoxic models of Parkinson’s disease, including the MPTP model, have been detailed.