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N-Acetyl-L-leucyl-L-leucyl-L-methional

Catalog No.GC50002

Cathepsin inhibitor

Products are for research use only. Not for human use. We do not sell to patients.

N-Acetyl-L-leucyl-L-leucyl-L-methional Chemical Structure

Cas No.: 145757-50-2

Size Price Stock Qty
10 mg
$230.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Very potent inhibitor of cathepsin L (Ki = 0.6 nM) and the strongest inhibitor of cathepsin B (Ki = 100 nM) amongst the peptide aldehydes. Also inhibits processing of malaria aspartic hemoglobinases plasmepsins I and II in vitro.

Francis et al (1997) Biosynthesis and maturation of the malaria aspartic hemogloninases plasmepsins I and II. J.Biol.Chem. 272 14961 PMID:9169469 |Sasaki et al (1990) Inhibitory effect of di- and tripeptidyl aldehydes on calpains and cathepsins. J.Enzyme Inhib. 3 195 PMID:2079636

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