N-Hydroxysulfosuccinimide (sodium salt) (Synonyms: Sulfo-NHS) |
| Catalog No.GC44398 |
N-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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Cas No.: 106627-54-7
Sample solution is provided at 25 µL, 10mM.
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N-Hydroxysulfosuccinimide (sulfo-NHS) is a modifying reagent that, in the presence of a cross-linking reagent like carbodiimide or EDAC, converts carboxyl groups to amine-reactive sulfo-NHS esters. The cross-linker converts the carboxylic acid to an unstable o-acylisourea intermediate, which then reacts with the primary amine of sulfo-NHS to produce the stable product.
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