PROTAC ER Degrader-3 |
| Catalog No.GC34734 |
PROTAC ER Degrader-3 is an intermediate for synthesis of PAC. PAC, consists the ADCs linker and PROTACs, conjugated to an antibody. PAC extracts from patent WO2017201449A1, compound LP2. PAC conjugated to an antibody is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2158322-29-1
Sample solution is provided at 25 µL, 10mM.
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PROTAC ER Degrader-3 is an intermediate for synthesis of PAC. PAC comprises an antibody conjugated via a linker to a PROTAC. PAC extracts from patent WO2017201449A1, compound LP2. PAC is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab).
[1]. Thomas Pillow, et al. Protac antibody conjugates and methods of use. WO2017201449A1.
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