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Other Apoptosis

Products for  Other Apoptosis

  1. Cat.No. Product Name Information
  2. GC10350 TIC10 isomer

    Potent Akt/ERK inhibitor

     TIC10 isomer  Chemical Structure
  3. GC45213 α-NETA Choline acetyltransferase (ChAT) mediates the synthesis of the neurotransmitter acetylcholine from acetyl-CoA and choline. α-NETA  Chemical Structure
  4. GC46008 (±)-Thalidomide-d4 An internal standard for the quantification of (±)-thalidomide (±)-Thalidomide-d4  Chemical Structure
  5. GC45256 (+)-ar-Turmerone (+)-ar-Turmerone is an aromatic compound from the rhizomes of C. (+)-ar-Turmerone  Chemical Structure
  6. GC41345 (-)-α-Bisabolol (-)-α-Bisabolol ((-)-α-Bisabolol), a monocyclic sesquiterpene alcohol, exerts antioxidant, anti-inflammatory, and anti-apoptotic activities. (-)-α-Bisabolol  Chemical Structure
  7. GC40698 (-)-Perillyl Alcohol (-)-Perillyl Alcohol is a monoterpene found in lavender, inhibits farnesylation of Ras, upregulates the mannose-6-phosphate receptor and induces apoptosis. Anti-cancer activity. (-)-Perillyl Alcohol  Chemical Structure
  8. GC34965 (20S)-Protopanaxatriol An active ginsenoside metabolite (20S)-Protopanaxatriol  Chemical Structure
  9. GC34981 (E)-Flavokawain A (E)-Flavokawain A, a chalcone extracted from Kava, has anticarcinogenic effect. (E)-Flavokawain A induces apoptosis in bladder cancer cells by involvement of bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. (E)-Flavokawain A  Chemical Structure
  10. GC34125 (E)-[6]-Dehydroparadol (E)-[6]-Dehydroparadol, an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator. (E)-[6]-Dehydroparadol can inhibit the growth and induce the apoptosis of human cancer cells. (E)-[6]-Dehydroparadol  Chemical Structure
  11. GN10783 (R) Ginsenoside Rh2 (R) Ginsenoside Rh2  Chemical Structure
  12. GC15104 (R)-(+)-Etomoxir sodium salt Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig. (R)-(+)-Etomoxir sodium salt  Chemical Structure
  13. GC41716 (R)-CR8 Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. (R)-CR8  Chemical Structure
  14. GC19541 (rac)-Antineoplaston A10

    (rac)-Antineoplaston A10 is the racemate of Antineoplaston A10

    (rac)-Antineoplaston A10  Chemical Structure
  15. GC10098 (S)-10-Hydroxycamptothecin inhibitor of topoisomerase I (S)-10-Hydroxycamptothecin  Chemical Structure
  16. GC11965 (±)-Huperzine A A neuroprotective AChE inhibitor (±)-Huperzine A  Chemical Structure
  17. GC11988 15-acetoxy Scirpenol mycotoxin that induce apoptotic cell death 15-acetoxy Scirpenol  Chemical Structure
  18. GC11720 17-AAG (KOS953) An inhibitor of Hsp90 17-AAG (KOS953)  Chemical Structure
  19. GC13044 17-DMAG (Alvespimycin) HCl 17-DMAG (Alvespimycin) HCl (17-DMAG hydrochloride; KOS-1022; BMS 826476) is a potent inhibitor of Hsp90, binding to Hsp90 with EC50 of 62±29 nM. 17-DMAG (Alvespimycin) HCl  Chemical Structure
  20. GN10065 2-Atractylenolide 2-Atractylenolide  Chemical Structure
  21. GC17430 2-Deoxy-D-glucose

    2-Deoxy-D-glucose (2DG), is a glucose analogue, act as competitive glycolytic inhibitor.

    2-Deoxy-D-glucose  Chemical Structure
  22. GC38318 2-Methoxycinnamaldehyde 2-Methoxycinnamaldehyde (o-Methoxycinnamaldehyde) is a natural compound of Cinnamomum cassia, with antitumor activity. 2-Methoxycinnamaldehyde inhibits proliferation and induces apoptosis by mitochondrial membrane potential (ΔΨm) loss, activation of both caspase-3 and caspase-9. 2-Methoxycinnamaldehyde effectively inhibits platelet-derived growth factor (PDGF)-induced HASMC migration. 2-Methoxycinnamaldehyde  Chemical Structure
  23. GC15084 2-Methoxyestradiol (2-MeOE2) 2-Methoxyestradiol (2-MeOE2/2-Me) is a HIF-1α inhibitor that inhibits HIF-1α accumulation and HIF transcriptional activity. 2-Methoxyestradiol can trigger p53-induced apoptosis and has potential antitumor activity.. 2-Methoxyestradiol (2-MeOE2)  Chemical Structure
  24. GN10800 20(S)-NotoginsenosideR2 20(S)-NotoginsenosideR2  Chemical Structure
  25. GC35112 3'-Hydroxypterostilbene 3'-Hydroxypterostilbene is a Pterostilbene analogue. 3'-Hydroxypterostilbene inhibits the growth of COLO 205, HCT-116 and HT-29 cells with IC50s of 9.0, 40.2 and 70.9 ?M, respectively. 3'-Hydroxypterostilbene significantly down-regulates PI3K/Akt and MAPKs signaling pathways and effectively inhibits the growth of human colon cancer cells by inducing apoptosis and autophagy. 3'-Hydroxypterostilbene can be used for the research of cancer. 3'-Hydroxypterostilbene  Chemical Structure
  26. GC35106 3-Dehydrotrametenolic acid 3-?Dehydrotrametenolic acid, isolated from the sclerotium of Poria cocos, is a lactate dehydrogenase (LDH) inhibitor. 3-?Dehydrotrametenolic acid promotes adipocyte differentiation in vitro and acts as an insulin sensitizer in vivo. 3-?Dehydrotrametenolic acid induces apoptosis and has anticancer activity. 3-Dehydrotrametenolic acid  Chemical Structure
  27. GC17394 3-Nitropropionic acid 3-Nitropropionic acid (β-Nitropropionic acid) is an irreversible inhibitor of succinate dehydrogenase. 3-Nitropropionic acid  Chemical Structure
  28. GC35099 3-O-Acetyloleanolic acid 3-O-Acetyloleanolic acid (3AOA), an oleanolic acid derivative isolated from the seeds of Vigna sinensis K., induces in cancer and also exhibits anti-angiogenesis activity. 3-O-Acetyloleanolic acid  Chemical Structure
  29. GC32767 3BDO A butyrolactone derivative and autophagy inhibitor 3BDO  Chemical Structure
  30. GC42346 4-bromo A23187

    4-bromo A23187 is a halogenated analog of the highly selective calcium ionophore A23187.

    4-bromo A23187  Chemical Structure
  31. GC30896 4-Hydroxybenzyl alcohol A phenol with diverse biological activities 4-Hydroxybenzyl alcohol  Chemical Structure
  32. GC35138 4-Methyldaphnetin 4-Methyldaphnetin is a precursor in the synthesis of derivatives of 4-methyl coumarin. 4-Methyldaphnetin has potent, selective anti-proliferative and apoptosis-inducing effects on several cancer cell lines. 4-Methyldaphnetin possesses radical scavenging property and strongly inhibits membrane lipid peroxidation. 4-Methyldaphnetin  Chemical Structure
  33. GC10468 4EGI-1 Competitive eIF4E/eIF4G interaction inhibitor 4EGI-1  Chemical Structure
  34. GC35150 5,7,4'-Trimethoxyflavone 5,7,4'-Trimethoxyflavone is isolated from Kaempferia parviflora (KP) that is a famous medicinal plant from Thailand. 5,7,4'-Trimethoxyflavone induces apoptosis, as evidenced by increments of sub-G1 phase, DNA fragmentation, annexin-V/PI staining, the Bax/Bcl-xL ratio, proteolytic activation of caspase-3, and degradation of poly (ADP-ribose) polymerase (PARP) protein.5,7,4'-Trimethoxyflavone is significantly effective at inhibiting proliferation of SNU-16 human gastric cancer cells in a concentration dependent manner. 5,7,4'-Trimethoxyflavone  Chemical Structure
  35. GC35147 5-(N,N-Hexamethylene)-amiloride An amiloride derivative with diverse biological activities 5-(N,N-Hexamethylene)-amiloride  Chemical Structure
  36. GC45356 5-Aminolevulinic Acid (hydrochloride)   5-Aminolevulinic Acid (hydrochloride)  Chemical Structure
  37. GN10093 6-gingerol 6-gingerol  Chemical Structure
  38. GC16853 7,8-Dihydroxyflavone Tyrosine kinase receptor B (TrkB) agonist 7,8-Dihydroxyflavone  Chemical Structure
  39. GC17119 8-Prenylnaringenin estrogen receptor inhibitor 8-Prenylnaringenin  Chemical Structure
  40. GC39152 9-ING-41 9-ING-41 is a maleimide-based ATP-competitive and selective glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 of 0.71 μM. 9-ING-41 significantly leads to cell cycle arrest, autophagy and apoptosis in cancer cells. 9-ING-41 has anticancer activity and has the potential for enhancing the antitumor effects of chemotherapeutic drugs. 9-ING-41  Chemical Structure
  41. GN10035 9-Methoxycamptothecin 9-Methoxycamptothecin  Chemical Structure
  42. GC11200 A23187

    A23187, free acid is a Ca2+ ionophore

    A23187  Chemical Structure
  43. GC35216 AAPK-25 AAPK-25 is a potent and selective Aurora/PLK dual inhibitor with anti-tumor activity, which can cause mitotic delay and arrest cells in a prometaphase, reflecting by the biomarker histone H3Ser10 phosphorylation and followed by a surge in apoptosis. AAPK-25 targets Aurora-A, -B, and -C with Kd values ranging from 23-289 nM, as well as PLK-1, -2, and -3 with Kd values ranging from 55-456 nM. AAPK-25  Chemical Structure
  44. GC13805 Abacavir Abacavir  Chemical Structure
  45. GC35227 ACBI1 ACBI1 is a potent and cooperative SMARCA2, SMARCA4 and PBRM1 degrader with DC50s of 6, 11 and 32 nM, respectively. ACBI1 is a PROTAC degrader. ACBI1 shows anti-proliferative activity. ACBI1 induces apoptosis. ACBI1  Chemical Structure
  46. GC11786 Acetylcysteine

    Acetylcysteine is the N-acetyl derivative of CYSTEINE.

    Acetylcysteine  Chemical Structure
  47. GC17094 Acitretin

    Metabolite of etretinate

    Acitretin  Chemical Structure
  48. GC35242 Actein Actein is a triterpene glycoside isolated from the rhizomes of Cimicifuga foetida. Actein suppresses cell proliferation, induces autophagy and apoptosis through promoting ROS/JNK activation, and blunting AKT pathway in human bladder cancer. Actein has little toxicity in vivo. Actein  Chemical Structure
  49. GC16350 Actinonin

    Peptidomimetic antibiotic that inhibits aminopeptidases

    Actinonin  Chemical Structure
  50. GC10610 Adapalene RARβ and RARγ agonist Adapalene  Chemical Structure
  51. GC13959 Adarotene An atypical retinoid Adarotene  Chemical Structure
  52. GC11892 AEE788 (NVP-AEE788) AEE788 (NVP-AEE788) is an inhibitor of the EGFR and ErbB2 with IC50 values of 2 and 6 nM, respectively. AEE788 (NVP-AEE788)  Chemical Structure
  53. GC13168 AG 825 Selective ErbB2 inhibitor AG 825  Chemical Structure
  54. GC13697 AG-1024 Selective IGF-1R inhibitor AG-1024  Chemical Structure
  55. GC17881 AGK 2

    AGK2 is a selective SIRT2 inhibitor, with an IC50 of 3.

    AGK 2  Chemical Structure
  56. GC39620 AKOS-22 AKOS-22  Chemical Structure
  57. GC11589 AKT inhibitor VIII A potent inhibitor of Akt1 and Akt2 AKT inhibitor VIII  Chemical Structure
  58. GC35275 AKT-IN-3 AKT-IN-3 (compound E22) is a potent, orally active low hERG blocking Akt inhibitor, with 1.4 nM, 1.2 nM and 1.7 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-3 (compound E22) also exhibits good inhibitory activity against other AGC family kinases, such as PKA, PKC, ROCK1, RSK1, P70S6K, and SGK. AKT-IN-3 (compound E22) induces apoptosis and inhibits metastasis of cancer cells. AKT-IN-3  Chemical Structure
  59. GC16597 Alda 1

    ALDH2 activator

    Alda 1  Chemical Structure
  60. GC35288 Alkannin A naphthoquinone with diverse biological activities Alkannin  Chemical Structure
  61. GC32127 Alofanib (RPT835) Alofanib (RPT835) (RPT835) is a potent and selective allosteric inhibitor of fibroblast growth factor receptor 2 (FGFR2). Alofanib (RPT835)  Chemical Structure
  62. GC14314 Aloperine An alkaloid Aloperine  Chemical Structure
  63. GC35306 alpha-Mangostin alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM. alpha-Mangostin  Chemical Structure
  64. GC42776 Amarogentin

    A secoiridoid glycoside with diverse biological activities

    Amarogentin  Chemical Structure
  65. GN10484 Amentoflavone Amentoflavone  Chemical Structure
  66. GC12051 Amiloride HCl dihydrate Amiloride HCl dihydrate (MK-870 hydrochloride dihydrate) is an inhibitor of both epithelial sodium channel (ENaC[1]) and urokinase-type plasminogen activator receptor (uTPA[2]). Amiloride HCl dihydrate  Chemical Structure
  67. GC16391 Amuvatinib (MP-470, HPK 56) A multi-targeted RTK inhibitor Amuvatinib (MP-470, HPK 56)  Chemical Structure
  68. GN10045 Angelicin Angelicin  Chemical Structure
  69. GC11559 Anisomycin

    JNK agonist, potent and specific

    Anisomycin  Chemical Structure
  70. GC35361 Antineoplaston A10 Antineoplaston A10, a naturally occurring substance in human body, is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer. Antineoplaston A10  Chemical Structure
  71. GC15586 AP1903 AP1903 (AP1903) is a dimerizer agent that acts by cross-linking the FKBP domains. AP1903 (AP1903) dimerizes the Caspase 9 suicide switch and rapidly induces apoptosis. AP1903  Chemical Structure
  72. GC35367 APG-115 APG-115 (APG-115) is an orally active MDM2 protein inhibitor binding to MDM2 protein with IC50 and Ki values of 3.8 nM and 1 nM, respectively. APG-115 blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-dependent manner. APG-115  Chemical Structure
  73. GC16237 Apocynin Selective NADPH-oxidase inhibitor Apocynin  Chemical Structure
  74. GC14209 Apoptosis Activator 2 An activator of caspases Apoptosis Activator 2  Chemical Structure
  75. GC14411 Apoptozole inhibitor of heat shock protein 70 (Hsp70) Apoptozole  Chemical Structure
  76. GC10420 Apremilast (CC-10004) An orally available PDE4 inhibitor Apremilast (CC-10004)  Chemical Structure
  77. GC32692 APTO-253 (LOR-253) APTO-253 (LOR-253) (LOR-253) is a small molecule that inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 (LOR-253)  Chemical Structure
  78. GC14590 AR-42 (OSU-HDAC42)

    HDAC inhibitor,novel and potent

    AR-42 (OSU-HDAC42)  Chemical Structure
  79. GC19037 ARS-853 ARS-853 is a selective, covalent KRASG12C inhibitor with an IC50 of 2.5 uM. ARS-853  Chemical Structure
  80. GC12070 Ascorbic acid An electron donor Ascorbic acid  Chemical Structure
  81. GN10702 Asiatic acid Asiatic acid  Chemical Structure
  82. GN10534 Asiaticoside Asiaticoside  Chemical Structure
  83. GC19041 ASK1-IN-1 ASK1-IN-1 is a potent, orally available and selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 of 2.87 nM. ASK1-IN-1  Chemical Structure
  84. GN10064 Asperosaponin VI Asperosaponin VI  Chemical Structure
  85. GN10561 astragalin astragalin  Chemical Structure
  86. GC18109 Astragaloside A anti-hypertension, positive inotropic action, anti-inflammation, and anti-myocardial injury Astragaloside A  Chemical Structure
  87. GC35415 Astramembrangenin Astramembrangenin  Chemical Structure
  88. GC15870 AT7519 Multi-CDK inhibitor AT7519  Chemical Structure
  89. GC13998 AT7519 Hydrochloride A Cdk inhibitor AT7519 Hydrochloride  Chemical Structure
  90. GC10638 AT9283 A broad spectrum kinase inhibitor AT9283  Chemical Structure
  91. GC18133 ATB-346 ATB-346 (ATB-346), an orally active non-steroidal anti-inflammatory drug (NSAID), inhibits cyclooxygenase-1 and 2 (COX-1 and 2). ATB-346  Chemical Structure
  92. GN10394 Atractylenolide III Atractylenolide III  Chemical Structure
  93. GC13332 Aurora A Inhibitor I A potent and selective inhibitor of Aurora A kinase Aurora A Inhibitor I  Chemical Structure
  94. GC15295 AUY922 (NVP-AUY922) An Hsp90 inhibitor AUY922 (NVP-AUY922)  Chemical Structure
  95. GC17045 AXL1717 A potent and selective inhibitor of IGF-1R AXL1717  Chemical Structure
  96. GC15055 AZ 628

    Raf kinases,potent and ATP-competitive

    AZ 628  Chemical Structure
  97. GC13433 AZ 960 A JAK2 inhibitor AZ 960  Chemical Structure
  98. GC15033 Azathioprine purine synthesis and GTP-binding protein Rac1 activation inhibitor Azathioprine  Chemical Structure
  99. GC12660 AZD1208 A pan-Pim kinase inhibitor AZD1208  Chemical Structure
  100. GC13029 AZD2014 AZD2014 (AZD2014) is an ATP competitive mTOR inhibitor with an IC50 of 2.81 nM. AZD2014 inhibits both mTORC1 and mTORC2 complexes. AZD2014  Chemical Structure
  101. GC16380 AZD8055 MTOR inhibitor AZD8055  Chemical Structure

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