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Cardiovascular

Cardiovascular

Cardiovascular

The cardiovascular system consists of the heart, blood and blood vessels. These organs form the 3 major closed circulation systems in the body, i.e., the pulmonary, coronary and systemic circulations. Cardiovascular disease includes heart disease, vascular diseases of the brain and kidney, and peripheral arterial diseases. Cardiovascular disease is the leading cause of death globally. Studies on cardiovascular regulation are important to provide a better understanding of this group of diseases and to help improve the corresponding treatment.

Targets for  Cardiovascular

Products for  Cardiovascular

  1. Cat.No. Product Name Information
  2. GC52065 4-Methoxyphenyl-β-D-Glucopyranoside An aryl glycoside with ice recrystallization inhibitory activity 4-Methoxyphenyl-β-D-Glucopyranoside  Chemical Structure
  3. GC40053 5α,6α-epoxy Cholestanol An oxysterol and a metabolite of cholesterol produced by oxidation 5α,6α-epoxy Cholestanol  Chemical Structure
  4. GC40782 5(Z),11(Z),14(Z)-Eicosatrienoic Acid 5(Z),11(Z),14(Z)-Eicosatrienoic acid is a polyunsaturated fatty acid found in various natural sources including maritime pine (Pinus pinaster) seed oil (MPSO), gymnospermae leaves and seeds, and freshwater gastropods. 5(Z),11(Z),14(Z)-Eicosatrienoic Acid  Chemical Structure
  5. GC42498 5-chloro Hydrochlorothiazide 5-chloro Hydrochlorothiazide is a derivative of hydrochlorothiazide, which is a diuretic and antihypertensive agent that increases renal excretion of sodium, potassium, chloride, and bicarbonate ions by inhibiting tubular reabsorptive mechanisms. 5-chloro Hydrochlorothiazide  Chemical Structure
  6. GC45357 5-Chlorouracil   5-Chlorouracil  Chemical Structure
  7. GC40336 5-cis Carbaprostacyclin 5-cis Carbaprostacyclin is a stable analog of PGI2 and an isomer of carbaprostacyclin. 5-cis Carbaprostacyclin  Chemical Structure
  8. GC41483 5-hydroxy Propranolol 5-hydroxy Propranolol is a metabolite of propranolol, a β-adrenergic receptor antagonist. 5-hydroxy Propranolol  Chemical Structure
  9. GC42563 5-methyl-2-HOBA (hydrochloride) 5-methyl-2-HOBA is an isoketal scavenger. 5-methyl-2-HOBA (hydrochloride)  Chemical Structure
  10. GC46706 5-Methyltetrahydrofolic Acid (hydrate) A biologically active form of folic acid 5-Methyltetrahydrofolic Acid (hydrate)  Chemical Structure
  11. GC41423 5-trans Prostaglandin E2 5-trans PGE2 occurs naturally in some gorgonian corals and is a common impurity in commercial lots of PGE1. 5-trans Prostaglandin E2  Chemical Structure
  12. GC40585 6α-Prostaglandin I1 6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions. 6α-Prostaglandin I1  Chemical Structure
  13. GC49629 6β-hydroxy Prednisolone A metabolite of prednisolone 6β-hydroxy Prednisolone  Chemical Structure
  14. GC40586 6β-Prostaglandin I1 6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions. 6β-Prostaglandin I1  Chemical Structure
  15. GC40535 6,15-diketo-13,14-dihydro Prostaglandin F1α 6,15-diketo-13,14-dihydro PGF1α is a metabolite of PGI2. 6,15-diketo-13,14-dihydro Prostaglandin F1α  Chemical Structure
  16. GC18219 6-hydroxy Warfarin 6-hydroxy Warfarin is a metabolite of (+)-warfarin , which is a weaker vitamin K antagonist than (-)-warfarin . 6-hydroxy Warfarin  Chemical Structure
  17. GC18820 6-keto Prostaglandin E1 6-keto PGE1 is a metabolite isolated after the incubation of PGI2 with rabbit liver microsomes. 6-keto Prostaglandin E1  Chemical Structure
  18. GC40202 7α-hydroxy Cholesterol-d7

    7α-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7α-hydroxy cholesterol by GC- or LC-MS.

    7α-hydroxy Cholesterol-d7  Chemical Structure
  19. GC40201 7β-hydroxy Cholesterol-d7 7β-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7β-hydroxy cholesterol by GC- or LC-MS. 7β-hydroxy Cholesterol-d7  Chemical Structure
  20. GC46241 7-keto Cholesterol-d7

    7-keto Cholesterol is a bioactive sterol and a major oxysterol component of oxidized LDL

    7-keto Cholesterol-d7  Chemical Structure
  21. GC18737 8-iso Prostaglandin E1 Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin. 8-iso Prostaglandin E1  Chemical Structure
  22. GC42634 9(R)-HODE cholesteryl ester 9(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. 9(R)-HODE cholesteryl ester  Chemical Structure
  23. GC19460 9(S)-HODE 9(S)-HODE is produced by the lipoxygenation of linoleic acid in both plants and animals. 9(S)-HODE  Chemical Structure
  24. GC42635 9(S)-HODE cholesteryl ester 9(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. 9(S)-HODE cholesteryl ester  Chemical Structure
  25. GC40338 9-deoxy-9-methylene Prostaglandin E2 9-deoxy-9-methylene Prostaglandin E2 (9-deoxy-9-methylene PGE2) is a stable, isosteric analog of PGE2. 9-deoxy-9-methylene Prostaglandin E2  Chemical Structure
  26. GA20031 A 71915 A 71915 is a highly potent and competitive natriuretic peptide receptor A (ANP, NPRA) antagonist (pKi= 9.18). A 71915  Chemical Structure
  27. GC48486 AAA A GPR75 antagonist AAA  Chemical Structure
  28. GC49576 Abnormal Cannabidiol-d3 Internal standard for the quantification of abnormal cannabidiol Abnormal Cannabidiol-d3  Chemical Structure
  29. GP10121 Ac-Endothelin-1 (16-21), human Ac-Endothelin-1 (16-21), human  Chemical Structure
  30. GC52058 Acebutolol Acebutolol is an orally active β1 adrenergic receptor (β1AR) antagonist. Acebutolol  Chemical Structure
  31. GC42690 Acecainide (hydrochloride) Acecainide is an active metabolite of the class III antiarrhythmic procainamide. Acecainide (hydrochloride)  Chemical Structure
  32. GC49614 Acenocoumarol-d4 Acenocoumarol-d4 is deuterium labeled Acenocoumarol. Acenocoumarol-d4  Chemical Structure
  33. GC46782 Acetochlor An herbicide Acetochlor  Chemical Structure
  34. GP10059 Acetyl Angiotensinogen (1-14), porcine Acetyl Angiotensinogen (1-14), porcine  Chemical Structure
  35. GC18474 Acetyldigitoxin Acetyldigitoxin is cardiac glycoside and an inhibitor of the Na+/K+ ATPase with an IC50 value of 5 nM in isolated rat pinealocytes. Acetyldigitoxin  Chemical Structure
  36. GC49406 ACT-373898 A metabolite of macitentan ACT-373898  Chemical Structure
  37. GC46805 Adefovir-d4 An internal standard for the quantification of adefovir Adefovir-d4  Chemical Structure
  38. GP10113 Adrenomedullin (1-12), human

    An N-terminal fragment of adrenomedullin

    Adrenomedullin (1-12), human  Chemical Structure
  39. GC42738 Adrenomedullin (13-52) (human) (trifluoroacetate salt) Adrenomedullin (13-52) is a truncated form of adrenomedullin (1-52). Adrenomedullin (13-52) (human) (trifluoroacetate salt)  Chemical Structure
  40. GC42746 AFP 07 (free acid) Prostaglandin I2 is an unstable prostanoid which, through the 'I prostanoid' (IP) receptor, inhibits platelet aggregation and promotes vasodilatation in pulmonary vascular beds. AFP 07 (free acid)  Chemical Structure
  41. GC46820 AHU377-d4 AHU377-d4 (AHU-377-d4) is the deuterium labeled Sacubitril. AHU377-d4  Chemical Structure
  42. GC49110 AICA Ribonucleotide An AMPK activator AICA Ribonucleotide  Chemical Structure
  43. GC46821 Ajoene A disulfide with diverse biological activities Ajoene  Chemical Structure
  44. GC52023 Alfuzosin-d7 An internal standard for the quantification of alfuzosin Alfuzosin-d7  Chemical Structure
  45. GC46835 Alyssin An isothiocyanate with diverse biological activities Alyssin  Chemical Structure
  46. GC49262 Alytesin (trifluoroacetate salt) A neuropeptide with diverse biological activities Alytesin (trifluoroacetate salt)  Chemical Structure
  47. GC42778 Amauromine Amauromine is a neutral antagonist of the cannabinoid (CB) receptor CB1 that is selective for CB1 (Ki = 178 nM; Kb = 66.6 nM) over CB2, with no activity at CB2 receptors at concentrations up to 10 μM. Amauromine  Chemical Structure
  48. GC49638 Ambrisentan-d3 An internal standard for the quantification of ambrisentan Ambrisentan-d3  Chemical Structure
  49. GC46842 Amiodarone-d4 (hydrochloride) An internal standard for the quantification of amiodarone Amiodarone-d4 (hydrochloride)  Chemical Structure
  50. GC46845 Amlodipine-d4 (maleate) An internal standard for the quantification of amlodipine Amlodipine-d4 (maleate)  Chemical Structure
  51. GP10099 amyloid A protein fragment [Homo sapiens] Apolipoproteins related to HDL in plasma amyloid A protein fragment [Homo sapiens]  Chemical Structure
  52. GP10077 Angiotensin (1-7)

    Ang-(1-7) (H - Asp - Arg - Val - Tyr - Ile - His - Pro - OH) is an endogenous peptide fragment that can be produced from Ang I or Ang II via endo- or carboxy-peptidases respectively[1].

    Angiotensin (1-7)  Chemical Structure
  53. GP10074 Angiotensin 1/2 (1-5) Angiotensin 1/2 (1-5)  Chemical Structure
  54. GP10067 Angiotensin 1/2 (1-6) Angiotensin 1/2 (1-6)  Chemical Structure
  55. GP10144 Angiotensin 1/2 (1-7) amide Angiotensin 1/2 (1-7) amide  Chemical Structure
  56. GP10012 Angiotensin 1/2 (1-8) amide

    Vasoconstrictor

    Angiotensin 1/2 (1-8) amide  Chemical Structure
  57. GP10025 Angiotensin 1/2 (1-9) Angiotensin 1/2 (1-9)  Chemical Structure
  58. GP10045 Angiotensin 1/2 (2-7)

    Vasoconstrictor

    Angiotensin 1/2 (2-7)  Chemical Structure
  59. GP10079 Angiotensin 1/2 (5-7) Angiotensin 1/2 (5-7)  Chemical Structure
  60. GP10120 Angiotensin 1/2 + A (2 - 8) Vasoconstrictor Angiotensin 1/2 + A (2 - 8)  Chemical Structure
  61. GC52415 Angiotensin A (trifluoroacetate salt) An AT1 and AT2 receptor agonist and active metabolite of angiotensin II Angiotensin A (trifluoroacetate salt)  Chemical Structure
  62. GP10087 Angiotensin I (human, mouse, rat) Angiotensin I (human, mouse, rat)  Chemical Structure
  63. GC42808 Angiotensin I (human, rat, mouse) (trifluoroacetate salt) Angiotensin I is an endogenous peptide that is converted to the vasoconstrictor angiotensin II by angiotensin-converting enzyme (ACE). Angiotensin I (human, rat, mouse) (trifluoroacetate salt)  Chemical Structure
  64. GP10023 Angiotensin II

    An agonist at AT1 and AT2 receptors

    Angiotensin II  Chemical Structure
  65. GC42809 Angiotensin II (3-8) (human, rat, mouse) (trifluoroacetate salt)

    Angiotensin II (3-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II.

    Angiotensin II (3-8) (human, rat, mouse) (trifluoroacetate salt)  Chemical Structure
  66. GC46856 Angiotensin II (5-8) (human, rat, mouse) (trifluoroacetate salt)

    An endogenous angiotensin II fragment

    Angiotensin II (5-8) (human, rat, mouse) (trifluoroacetate salt)  Chemical Structure
  67. GP10110 Angiotensin III (human, mouse) An agonist at AT1 and AT2 receptors Angiotensin III (human, mouse)  Chemical Structure
  68. GP10137 ANP (1-11), rat ANP (1-11), rat  Chemical Structure
  69. GC42821 AP219 AP39 is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria. AP219  Chemical Structure
  70. GC52427 Apelin-12 (human, mouse, rat, bovine) (acetate) An endogenous agonist of the APJ receptor Apelin-12 (human, mouse, rat, bovine) (acetate)  Chemical Structure
  71. GC49314 Arecaidine propargyl ester (hydrobromide) A muscarinic M2 agonist Arecaidine propargyl ester (hydrobromide)  Chemical Structure
  72. GC46879 Argatroban-d3 (hydrochloride) An internal standard for the quantification of argatroban Argatroban-d3 (hydrochloride)  Chemical Structure
  73. GC48997 Argipressin (acetate) A peptide hormone with vasoconstrictive and antidiuretic activities Argipressin (acetate)  Chemical Structure
  74. GC40848 Aspalatone Aspalatone is an anti-platelet aggregator (IC50 = 180 μM, in vitro) that prolongs bleeding time significantly in a rodent model of thromboembolism. Aspalatone  Chemical Structure
  75. GC39554 AT2 receptor agonist C21 An AT2 receptor agonist AT2 receptor agonist C21  Chemical Structure
  76. GC46889 Atorvastatin (calcium salt hydrate) An HMG-CoA reductase inhibitor Atorvastatin (calcium salt hydrate)  Chemical Structure
  77. GC49421 Atorvastatin lactone-d5 An internal standard for the quantification of atorvastatin lactone Atorvastatin lactone-d5  Chemical Structure
  78. GC46890 Atorvastatin-d5 (calcium salt) An internal standard for the quantification of atorvastatin Atorvastatin-d5 (calcium salt)  Chemical Structure
  79. GC42869 Atpenin A5 Mitochondrial complex II (succinate dehydrogenase or succinate:ubiquinone oxidoreductase) is a functional member of the Krebs cycle and the aerobic respiratory chain that couples the oxidation of succinate to fumarate with the reduction of quinone to quinol. Atpenin A5  Chemical Structure
  80. GP10061 Atrial Natriuretic Factor (1-29), chicken Atrial Natriuretic Factor (1-29), chicken, (C130H223N51O41S5), a peptide with the sequence H2N-SPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH-OH, MW= 3316.8. Atrial Natriuretic Factor (1-29), chicken  Chemical Structure
  81. GC52359 ATX-100 An ionizable cationic lipid ATX-100  Chemical Structure
  82. GC49784 AZD 2716 An sPLA2 inhibitor AZD 2716  Chemical Structure
  83. GC42890 Azelaoyl PAF Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes via the nuclear receptor PPARγ. Azelaoyl PAF  Chemical Structure
  84. GC49057 Azelastine-13C-d3 (hydrochloride) An internal standard for the quantification of azelastine Azelastine-13C-d3 (hydrochloride)  Chemical Structure
  85. GC18313 BAR501 Impurity BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR501 Impurity  Chemical Structure
  86. GC48589 Bassianin A fungal metabolite Bassianin  Chemical Structure
  87. GC46911 Beauveriolide I A cyclodepsipeptide inhibitor of lipid droplet formation Beauveriolide I  Chemical Structure
  88. GC46912 Beauveriolide III

    A cyclodepsipeptide inhibitor of lipid droplet formation

    Beauveriolide III  Chemical Structure
  89. GC46913 Benazepril-d5 (hydrochloride) An internal standard for the quantification of benazapril Benazepril-d5 (hydrochloride)  Chemical Structure
  90. GC42913 Benazeprilat

    Benazeprilat is an inhibitor of angiotensin-converting enzyme (ACE; IC50 = 0.28 nM in plasma from dog) and the active metabolite of the prodrug benazepril.

    Benazeprilat  Chemical Structure
  91. GC49836 Benoxaprofen Benoxaprofen (LRCL 3794) is a potent and long-acting anti-inflammatory and antipyretic compound. Benoxaprofen  Chemical Structure
  92. GC49403 Benzarone An active metabolite of benzbromarone Benzarone  Chemical Structure
  93. GC42924 Beraprost (sodium salt) Beraprost is an analog of prostacyclin in which the unstable enol-ether has been replaced by a benzofuran ether function. Beraprost (sodium salt)  Chemical Structure
  94. GC49387 Berberine-d6 (chloride) An internal standard for the quantification of berberine Berberine-d6 (chloride)  Chemical Structure
  95. GC42941 Bis(methylthio)gliotoxin Bis(methylthio)gliotoxin is a fungal metabolite originally isolated from G. Bis(methylthio)gliotoxin  Chemical Structure
  96. GC18716 Bisindolylmaleimide XI (hydrochloride) Bisindolylmaleimide XI (BIM XI) is a selective, cell-permeable protein kinase C (PKC) inhibitor that displays 10-fold greater selectivity for PKCα (IC50 = 9 nM) and 4-fold greater selectivity for PKCβI (IC50 = 28 nM) over Ca2+-independent PKCε (IC50 = 108 nM). Bisindolylmaleimide XI (hydrochloride)  Chemical Structure
  97. GP10071 BNP (1-32), human BNP (1-32), human  Chemical Structure
  98. GA20982 Boc-D-Phe-Pro-OH A synthetic intermediate Boc-D-Phe-Pro-OH  Chemical Structure
  99. GC42966 Bopindolol (malonate) Bopindolol is a non-selective β-adrenergic receptor antagonist. Bopindolol (malonate)  Chemical Structure
  100. GC48620 BPKDi A PKD inhibitor BPKDi  Chemical Structure
  101. GC49885 BQ-3020 (trifluoroacetate salt) A peptide ETB receptor antagonist BQ-3020 (trifluoroacetate salt)  Chemical Structure

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