Cardiovascular
Cardiovascular
The cardiovascular system consists of the heart, blood and blood vessels. These organs form the 3 major closed circulation systems in the body, i.e., the pulmonary, coronary and systemic circulations. Cardiovascular disease includes heart disease, vascular diseases of the brain and kidney, and peripheral arterial diseases. Cardiovascular disease is the leading cause of death globally. Studies on cardiovascular regulation are important to provide a better understanding of this group of diseases and to help improve the corresponding treatment.
Targets for Cardiovascular
Products for Cardiovascular
- Cat.No. Product Name Information
- GC52065 4-Methoxyphenyl-β-D-Glucopyranoside An aryl glycoside with ice recrystallization inhibitory activity
- GC40053 5α,6α-epoxy Cholestanol An oxysterol and a metabolite of cholesterol produced by oxidation
- GC40782 5(Z),11(Z),14(Z)-Eicosatrienoic Acid 5(Z),11(Z),14(Z)-Eicosatrienoic acid is a polyunsaturated fatty acid found in various natural sources including maritime pine (Pinus pinaster) seed oil (MPSO), gymnospermae leaves and seeds, and freshwater gastropods.
- GC42498 5-chloro Hydrochlorothiazide 5-chloro Hydrochlorothiazide is a derivative of hydrochlorothiazide, which is a diuretic and antihypertensive agent that increases renal excretion of sodium, potassium, chloride, and bicarbonate ions by inhibiting tubular reabsorptive mechanisms.
- GC45357 5-Chlorouracil
- GC40336 5-cis Carbaprostacyclin 5-cis Carbaprostacyclin is a stable analog of PGI2 and an isomer of carbaprostacyclin.
- GC41483 5-hydroxy Propranolol 5-hydroxy Propranolol is a metabolite of propranolol, a β-adrenergic receptor antagonist.
- GC42563 5-methyl-2-HOBA (hydrochloride) 5-methyl-2-HOBA is an isoketal scavenger.
- GC46706 5-Methyltetrahydrofolic Acid (hydrate) A biologically active form of folic acid
- GC41423 5-trans Prostaglandin E2 5-trans PGE2 occurs naturally in some gorgonian corals and is a common impurity in commercial lots of PGE1.
- GC40585 6α-Prostaglandin I1 6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions.
- GC49629 6β-hydroxy Prednisolone A metabolite of prednisolone
- GC40586 6β-Prostaglandin I1 6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions.
- GC40535 6,15-diketo-13,14-dihydro Prostaglandin F1α 6,15-diketo-13,14-dihydro PGF1α is a metabolite of PGI2.
- GC18219 6-hydroxy Warfarin 6-hydroxy Warfarin is a metabolite of (+)-warfarin , which is a weaker vitamin K antagonist than (-)-warfarin .
- GC18820 6-keto Prostaglandin E1 6-keto PGE1 is a metabolite isolated after the incubation of PGI2 with rabbit liver microsomes.
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GC40202
7α-hydroxy Cholesterol-d7
7α-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7α-hydroxy cholesterol by GC- or LC-MS.
- GC40201 7β-hydroxy Cholesterol-d7 7β-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7β-hydroxy cholesterol by GC- or LC-MS.
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GC46241
7-keto Cholesterol-d7
7-keto Cholesterol is a bioactive sterol and a major oxysterol component of oxidized LDL
- GC18737 8-iso Prostaglandin E1 Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin.
- GC42634 9(R)-HODE cholesteryl ester 9(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions.
- GC19460 9(S)-HODE 9(S)-HODE is produced by the lipoxygenation of linoleic acid in both plants and animals.
- GC42635 9(S)-HODE cholesteryl ester 9(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions.
- GC40338 9-deoxy-9-methylene Prostaglandin E2 9-deoxy-9-methylene Prostaglandin E2 (9-deoxy-9-methylene PGE2) is a stable, isosteric analog of PGE2.
- GA20031 A 71915 A 71915 is a highly potent and competitive natriuretic peptide receptor A (ANP, NPRA) antagonist (pKi= 9.18).
- GC48486 AAA A GPR75 antagonist
- GC49576 Abnormal Cannabidiol-d3 Internal standard for the quantification of abnormal cannabidiol
- GP10121 Ac-Endothelin-1 (16-21), human
- GC52058 Acebutolol Acebutolol is an orally active β1 adrenergic receptor (β1AR) antagonist.
- GC42690 Acecainide (hydrochloride) Acecainide is an active metabolite of the class III antiarrhythmic procainamide.
- GC49614 Acenocoumarol-d4 Acenocoumarol-d4 is deuterium labeled Acenocoumarol.
- GC46782 Acetochlor An herbicide
- GP10059 Acetyl Angiotensinogen (1-14), porcine
- GC18474 Acetyldigitoxin Acetyldigitoxin is cardiac glycoside and an inhibitor of the Na+/K+ ATPase with an IC50 value of 5 nM in isolated rat pinealocytes.
- GC49406 ACT-373898 A metabolite of macitentan
- GC46805 Adefovir-d4 An internal standard for the quantification of adefovir
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GP10113
Adrenomedullin (1-12), human
An N-terminal fragment of adrenomedullin
- GC42738 Adrenomedullin (13-52) (human) (trifluoroacetate salt) Adrenomedullin (13-52) is a truncated form of adrenomedullin (1-52).
- GC42746 AFP 07 (free acid) Prostaglandin I2 is an unstable prostanoid which, through the 'I prostanoid' (IP) receptor, inhibits platelet aggregation and promotes vasodilatation in pulmonary vascular beds.
- GC46820 AHU377-d4 AHU377-d4 (AHU-377-d4) is the deuterium labeled Sacubitril.
- GC49110 AICA Ribonucleotide An AMPK activator
- GC46821 Ajoene A disulfide with diverse biological activities
- GC52023 Alfuzosin-d7 An internal standard for the quantification of alfuzosin
- GC46835 Alyssin An isothiocyanate with diverse biological activities
- GC49262 Alytesin (trifluoroacetate salt) A neuropeptide with diverse biological activities
- GC42778 Amauromine Amauromine is a neutral antagonist of the cannabinoid (CB) receptor CB1 that is selective for CB1 (Ki = 178 nM; Kb = 66.6 nM) over CB2, with no activity at CB2 receptors at concentrations up to 10 μM.
- GC49638 Ambrisentan-d3 An internal standard for the quantification of ambrisentan
- GC46842 Amiodarone-d4 (hydrochloride) An internal standard for the quantification of amiodarone
- GC46845 Amlodipine-d4 (maleate) An internal standard for the quantification of amlodipine
- GP10099 amyloid A protein fragment [Homo sapiens] Apolipoproteins related to HDL in plasma
-
GP10077
Angiotensin (1-7)
Ang-(1-7) (H - Asp - Arg - Val - Tyr - Ile - His - Pro - OH) is an endogenous peptide fragment that can be produced from Ang I or Ang II via endo- or carboxy-peptidases respectively[1].
- GP10074 Angiotensin 1/2 (1-5)
- GP10067 Angiotensin 1/2 (1-6)
- GP10144 Angiotensin 1/2 (1-7) amide
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GP10012
Angiotensin 1/2 (1-8) amide
Vasoconstrictor
- GP10025 Angiotensin 1/2 (1-9)
-
GP10045
Angiotensin 1/2 (2-7)
Vasoconstrictor
- GP10079 Angiotensin 1/2 (5-7)
- GP10120 Angiotensin 1/2 + A (2 - 8) Vasoconstrictor
- GC52415 Angiotensin A (trifluoroacetate salt) An AT1 and AT2 receptor agonist and active metabolite of angiotensin II
- GP10087 Angiotensin I (human, mouse, rat)
- GC42808 Angiotensin I (human, rat, mouse) (trifluoroacetate salt) Angiotensin I is an endogenous peptide that is converted to the vasoconstrictor angiotensin II by angiotensin-converting enzyme (ACE).
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GP10023
Angiotensin II
An agonist at AT1 and AT2 receptors
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GC42809
Angiotensin II (3-8) (human, rat, mouse) (trifluoroacetate salt)
Angiotensin II (3-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II.
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GC46856
Angiotensin II (5-8) (human, rat, mouse) (trifluoroacetate salt)
An endogenous angiotensin II fragment
- GP10110 Angiotensin III (human, mouse) An agonist at AT1 and AT2 receptors
- GP10137 ANP (1-11), rat
- GC42821 AP219 AP39 is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria.
- GC52427 Apelin-12 (human, mouse, rat, bovine) (acetate) An endogenous agonist of the APJ receptor
- GC49314 Arecaidine propargyl ester (hydrobromide) A muscarinic M2 agonist
- GC46879 Argatroban-d3 (hydrochloride) An internal standard for the quantification of argatroban
- GC48997 Argipressin (acetate) A peptide hormone with vasoconstrictive and antidiuretic activities
- GC40848 Aspalatone Aspalatone is an anti-platelet aggregator (IC50 = 180 μM, in vitro) that prolongs bleeding time significantly in a rodent model of thromboembolism.
- GC39554 AT2 receptor agonist C21 An AT2 receptor agonist
- GC46889 Atorvastatin (calcium salt hydrate) An HMG-CoA reductase inhibitor
- GC49421 Atorvastatin lactone-d5 An internal standard for the quantification of atorvastatin lactone
- GC46890 Atorvastatin-d5 (calcium salt) An internal standard for the quantification of atorvastatin
- GC42869 Atpenin A5 Mitochondrial complex II (succinate dehydrogenase or succinate:ubiquinone oxidoreductase) is a functional member of the Krebs cycle and the aerobic respiratory chain that couples the oxidation of succinate to fumarate with the reduction of quinone to quinol.
- GP10061 Atrial Natriuretic Factor (1-29), chicken Atrial Natriuretic Factor (1-29), chicken, (C130H223N51O41S5), a peptide with the sequence H2N-SPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH-OH, MW= 3316.8.
- GC52359 ATX-100 An ionizable cationic lipid
- GC49784 AZD 2716 An sPLA2 inhibitor
- GC42890 Azelaoyl PAF Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes via the nuclear receptor PPARγ.
- GC49057 Azelastine-13C-d3 (hydrochloride) An internal standard for the quantification of azelastine
- GC18313 BAR501 Impurity BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1).
- GC48589 Bassianin A fungal metabolite
- GC46911 Beauveriolide I A cyclodepsipeptide inhibitor of lipid droplet formation
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GC46912
Beauveriolide III
A cyclodepsipeptide inhibitor of lipid droplet formation
- GC46913 Benazepril-d5 (hydrochloride) An internal standard for the quantification of benazapril
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GC42913
Benazeprilat
Benazeprilat is an inhibitor of angiotensin-converting enzyme (ACE; IC50 = 0.28 nM in plasma from dog) and the active metabolite of the prodrug benazepril.
- GC49836 Benoxaprofen Benoxaprofen (LRCL 3794) is a potent and long-acting anti-inflammatory and antipyretic compound.
- GC49403 Benzarone An active metabolite of benzbromarone
- GC42924 Beraprost (sodium salt) Beraprost is an analog of prostacyclin in which the unstable enol-ether has been replaced by a benzofuran ether function.
- GC49387 Berberine-d6 (chloride) An internal standard for the quantification of berberine
- GC42941 Bis(methylthio)gliotoxin Bis(methylthio)gliotoxin is a fungal metabolite originally isolated from G.
- GC18716 Bisindolylmaleimide XI (hydrochloride) Bisindolylmaleimide XI (BIM XI) is a selective, cell-permeable protein kinase C (PKC) inhibitor that displays 10-fold greater selectivity for PKCα (IC50 = 9 nM) and 4-fold greater selectivity for PKCβI (IC50 = 28 nM) over Ca2+-independent PKCε (IC50 = 108 nM).
- GP10071 BNP (1-32), human
- GA20982 Boc-D-Phe-Pro-OH A synthetic intermediate
- GC42966 Bopindolol (malonate) Bopindolol is a non-selective β-adrenergic receptor antagonist.
- GC48620 BPKDi A PKD inhibitor
- GC49885 BQ-3020 (trifluoroacetate salt) A peptide ETB receptor antagonist