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Home >> Signaling Pathways >> Neuroscience >> CGRP

CGRP

CGRP (calcitonin gene related peptide) is a potent peptide vasodilator and can function in the transmission of pain.

Products for  CGRP

  1. Cat.No. Product Name Information
  2. GC34944 β-CGRP, human TFA β-CGRP, human TFA Chemical Structure
  3. GC33595 β-CGRP, human (Human β-CGRP) β-CGRP, human (Human β-CGRP) (Human β-CGRP) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells. β-CGRP, human (Human β-CGRP) Chemical Structure
  4. GC34230 Adrenomedullin (1-50), rat Adrenomedullin (1-50), rat is a 50 amino acid peptide, which induces a selective arterial vasodilation via activation of CGRP1 receptor. Adrenomedullin (1-50), rat Chemical Structure
  5. GC35256 Adrenomedullin (11-50), rat Adrenomedullin (11-50), rat is the C-terminal fragment (11-50) of rat adrenomedullin. Adrenomedullin (11-50), rat Chemical Structure
  6. GC35257 Adrenomedullin (16-31), human Adrenomedullin (16-31), human is amino acid residues 16-31 fragment of human adrenomedullin (hADM). Adrenomedullin (16-31), human Chemical Structure
  7. GC32615 Adrenomedullin (AM) (22-52), human (22-52-Adrenomedullin (human)) Adrenomedullin (AM) (22-52), human (22-52-Adrenomedullin (human)), an NH2 terminal truncated adrenomedullin analogue, is an adrenomedullin receptor antagonist, and also antagonizes the calcitonin generelated peptide (CGRP) receptor in the hindlimb vascular bed of the cat. Adrenomedullin (AM) (22-52), human (22-52-Adrenomedullin (human)) Chemical Structure
  8. GC65596 Atogepant Atogepant (MK-8031) is an orally active and selective calcitonin gene–related peptide receptor (CGRP) antagonist. Atogepant Chemical Structure
  9. GC13705 BMS-927711 A CGRP receptor antagonist BMS-927711 Chemical Structure
  10. GC50320 Calcitonin (human) Endogenous calcitonin agonist; inhibits bone resorption Calcitonin (human) Chemical Structure
  11. GC34396 Calcitonin Gene Related Peptide (CGRP) (83-119), rat Calcitonin Gene Related Peptide (CGRP) (83-119), rat Chemical Structure
  12. GC34395 Calcitonin Gene Related Peptide (CGRP) (83-119), rat TFA Calcitonin Gene Related Peptide (CGRP) (83-119), rat TFA Chemical Structure
  13. GC32851 Calcitonin salmon (Salmon calcitonin) Calcitonin salmon, a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption. Calcitonin salmon (Salmon calcitonin) Chemical Structure
  14. GC16147 CGRP 8-37 (human) CGRP 8-37 (human) is a human calcitonin gene-related peptide (hCGRP) fragment and also an antagonist of CGRP receptor. CGRP 8-37 (human) Chemical Structure
  15. GC10927 CGRP 8-37 (rat) CGRP 8-37 (rat) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonist. CGRP 8-37 (rat) Chemical Structure
  16. GC31107 CGRP antagonist 1 CGRP antagonist 1 is a highly potent CGRP receptor antagonist with a Ki and IC50 of 35 and 57 nM, respectively. CGRP antagonist 1 Chemical Structure
  17. GC66408 Fremanezumab Fremanezumab (TEV-48125) is a humanized IgG2a monoclonal antibody that selectively and potently binds to calcitonin gene-related peptide (CGRP). CGRP is a 37-amino acid neuropeptide involved in central and peripheral pathophysiological events of migraine. Fremanezumab has the potential for chronic migraine research. Fremanezumab Chemical Structure
  18. GC66402 Galcanezumab Galcanezumab (LY 2951742) is a humanized IgG4 monoclonal antibody against the CGRP ligand. Galcanezumab can be used for migraine or cluster headaches research. Galcanezumab Chemical Structure
  19. GC18501 Kendomycin Kendomycin is a macrolide from Streptomyces which displays potent cytotoxicity against several carcinoma cell lines (GI50 < 100 nM). Kendomycin Chemical Structure
  20. GC16478 MK-0974 A CGRP receptor antagonist MK-0974 Chemical Structure
  21. GC16365 MK-3207 MK-3207 Chemical Structure
  22. GC11192 MK-3207 HCl MK-3207 (Hydrochloride) is a potent and orally bioavailable CGRP receptor antagonist with IC50 of 0.12 nM and Ki of 0.024 nM, and is highly selective versus human AM1, AM2, CTR, and AMY3. MK-3207 HCl Chemical Structure
  23. GC17233 Olcegepant Olcegepant Chemical Structure
  24. GC36795 Olcegepant hydrochloride Olcegepant hydrochloride (BIBN-4096 hydrochloride) is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and with a Ki of 14.4 pM for human CGRP. Olcegepant hydrochloride Chemical Structure
  25. GC15348 Pyridostigmine Bromide Reversible cholinesterase inhibitor Pyridostigmine Bromide Chemical Structure
  26. GC30341 Ubrogepant (MK-1602) Ubrogepant (MK-1602) (MK-1602) is a novel oral calcitonin gene-related peptide receptor (CGRP) antagonist in development for acute treatment of migraine. Ubrogepant (MK-1602) Chemical Structure
  27. GC62199 Vazegepant hydrochloride Vazegepant (BHV-3500) hydrochloride is a highly soluble CGRP receptor antagonist (hCGRP Ki= 0.023 nM). Vazegepant hydrochloride Chemical Structure

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