Cytoskeleton & Motor Proteins
Products for Cytoskeleton & Motor Proteins
- Cat.No. Product Name Information
- GC41268 (E)-2-Hexadecenal Sphingosine-1-phosphate (S1P), a bioactive lipid involved in many signaling processes, is irreversibly degraded by the membrane-bound S1P lyase.
- GC41701 (E)-2-Hexadecenal Alkyne (E)-2-Hexadecenal alkyne is an alkyne version of the sphingolipid degradation product (E)-2-hexadecenal that can be used as a click chemistry probe.
- GC41719 (R)-nitro-Blebbistatin (R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin, which is the inactive form of (-)-blebbistatin.
- GC41557 (S)-3'-amino Blebbistatin (S)-3'-amino Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases.
- GC41484 (S)-3'-hydroxy Blebbistatin (S)-3'-hydroxy Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases.
- GC52192 (S)-4'-nitro-Blebbistatin (S)-4'-nitro-Blebbistatin is a non-cytotoxic, photostable, fluorescent and specific Myosin II inhibitor, usd in the study of the specific role of myosin II in physiological, developmental, and cell biological studies.
- GC41739 (S)-nitro-Blebbistatin (S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases.
- GC49736 10-acetyl Docetaxel 10-acetyl Docetaxel (10-Acetyl docetaxel) is an analog of Docetaxel, with anticancer activity. Docetaxel is a microtubule disassembly inhibitor, with antimitotic activity.
- GC41110 16-epi Latrunculin B 16-epi Latrunculin B, first isolated from the Red Sea sponge N.
- GC48423 19-O-Acetylchaetoglobosin A A fungal metabolite with actin polymerization inhibitory and cytotoxic activities
- GC52029 2-Aminoflubendazole
- GC49244 4-oxo Isotretinoin An active metabolite of isotretinoin
- GC48721 6-O-Demethyl Griseofulvin A metabolite of griseofulvin
- GC40844 9-(2,2-Dicyanovinyl)julolidine 9-(2,2-Dicyanovinyl)julolidine (9-(2,2-Dicyanovinyl)julolidine), a molecular rotor and unique fluorescent dye, binds to tubulin and actin, and increases its fluorescence intensity drastically upon polymerization.
- GC25025 Abraxane Abraxane (Nab-Paclitaxel), a novel solvent-free taxane with the binding ratio of Paclitaxel to human serum albumin of 1:9, is an anti-microtubule drug that promotes microtubule aggregation in tubulin dimer and inhibits microtubule depolymerization to stabilize the microtubule system.
- GC18274 Amiprofos-methyl Amiprofos-methyl (APM) is a phosphoric amide herbicide.
- GC25075 Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222) Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222, Antibiotic C 15003P3) is a potent inhibitor of tubulin polymerization with IC50 of 3.4 μM.
- GC42933 Binucleine 2 Binucleine 2 is an isoform-specific and ATP-competitive inhibitor of Drosophila Aurora B kinase (Ki = 0.36 μM), a kinase involved in cell division.
- GC18408 BML-278 BML-278 is an activator of sirtuin 1 (SIRT1) that has an EC150 value (effective concentration able to increase the enzyme by 150%) of 1 uM.
- GC46946 BPC 157 (acetate) A pentadecapeptide with diverse biological activities
- GC45395 Cabazitaxel-d9 Cabazitaxel-d9 is deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.
- GC43135 Cambendazol Cambendazol is one of the most effective agents for the therapy of human strongyloidiasis and .
- GC40890 CAY10701 CAY10701 is a 7-deazahypoxanthine analog that prevents microtubule formation, blocking the proliferation of HeLa and MCF-7 cells (GI50s = 22 and 38 nM, respectively).
- GC52367 Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide A biotinylated and citrullinated mutant vimentin peptide
- GC52370 Citrullinated Vimentin (R144) (139-159)-biotin Peptide A biotinylated and citrullinated vimentin peptide
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GC40664
Colcemid
Colcemid is a cytoskeletal inhibitor that induces mitotic arrest in the G2/M phase or meiotic arrest in the vesicle rupture (GVBD) phase in mammalian cells or oocytes, respectively.
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GC47117
Colchicine-d6
An internal standard for the quantification of colchicine
- GC49913 Davunetide (acetate) A neuroprotective ADNP-derived peptide
- GC43469 Diminutol Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis.
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GC48968
Docetaxel (hydrate)
An analog of taxol with antitumor properties
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GC47250
Docetaxel-d9
An internal standard for the quantification of docetaxel
- GC49124 EN219 EN219 is a moderately selective synthetic covalent ligand against an N-terminal cysteine (C8) of RNF114 with an IC50 of 470 nM. EN219 inhibits RNF114-mediated autoubiquitination and p21 ubiquitination.
- GC48720 Griseofulvic Acid A metabolite of griseofulvin
- GC48688 Griseofulvin-d3 An internal standard for the quantification of griseofulvin
- GC40048 MPS1/TTK Inhibitor MPS1/TTK inhibitor is an inhibitor of monopolar spindle 1 (MPS1/TTK; IC50 = 5.8 nM), a kinase involved in mitotic spindle checkpoint signaling that is overexpressed in certain cancerous tumors.
- GC41564 MPT0B014 An inhibitor of tubulin polymerization
- GC18445 N-Deacetylcolchicine An inhibitor of microtubule polymerization
- GC49404 Paclitaxel C A taxoid and an inhibitor of microtubule depolymerization
- GC45944 para-amino-Blebbistatin A more stable and less phototoxic form of (–)-blebbistatin with enhanced water solubility
- GC44618 Phalloidin-AMCA Conjugate Phalloidin-AMCA conjugate is a blue fluorophore that specifically labels filamentous actin (F-actin).
- GC44620 Phalloidin-Tetramethylrhodamine Conjugate Phalloidin-retramethylrhodamine conjugate is an orange fluorescent probe (ex/em = 546/575 nm) that selectively binds to F-actin.
- GC48394 Phomopsinamine An inhibitor of microtubule polymerization
- GC49077 Podophyllotoxin-d6 An internal standard for the quantification of podophyllotoxin and picropodophyllotoxin
- GC44800 Quininib A CysLT1 and CysLT2 receptor antagonist
- GC45688 STX140 An estrogen sulfamate
- GC48119 Suprafenacine An inhibitor of tubulin polymerization with anticancer activity
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GC44976
Swinholide A
Swinholide A is a natural dimeric dilactone macrolide toxin that causes actin depolymerization in cells.
- GC45750 Thymosin β4 (human, mouse, rat, porcine, bovine) (acetate) An actin-sequestering peptide
- GC18763 TN-16 TN-16 is an inhibitor of microtubule polymerization (IC50 = 0.4-1.7 uM).
- GC52364 Vimentin (139-159)-biotin Peptide A biotinylated vimentin peptide
- GC52371 Vimentin (G146R) (139-159)-biotin Peptide A biotinylated mutant vimentin peptide
- GC45595 Vulpinic Acid
- GC18578 YK-3-237 An inhibitor of tubulin polymerization and activator of SIRT1