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Cytoskeleton & Motor Proteins

Products for  Cytoskeleton & Motor Proteins

  1. Cat.No. Product Name Information
  2. GC41268 (E)-2-Hexadecenal Sphingosine-1-phosphate (S1P), a bioactive lipid involved in many signaling processes, is irreversibly degraded by the membrane-bound S1P lyase. (E)-2-Hexadecenal  Chemical Structure
  3. GC41701 (E)-2-Hexadecenal Alkyne (E)-2-Hexadecenal alkyne is an alkyne version of the sphingolipid degradation product (E)-2-hexadecenal that can be used as a click chemistry probe. (E)-2-Hexadecenal Alkyne  Chemical Structure
  4. GC41719 (R)-nitro-Blebbistatin (R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin, which is the inactive form of (-)-blebbistatin. (R)-nitro-Blebbistatin  Chemical Structure
  5. GC41557 (S)-3'-amino Blebbistatin (S)-3'-amino Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-3'-amino Blebbistatin  Chemical Structure
  6. GC41484 (S)-3'-hydroxy Blebbistatin (S)-3'-hydroxy Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-3'-hydroxy Blebbistatin  Chemical Structure
  7. GC52192 (S)-4'-nitro-Blebbistatin (S)-4'-nitro-Blebbistatin is a non-cytotoxic, photostable, fluorescent and specific Myosin II inhibitor, usd in the study of the specific role of myosin II in physiological, developmental, and cell biological studies. (S)-4'-nitro-Blebbistatin  Chemical Structure
  8. GC41739 (S)-nitro-Blebbistatin (S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-nitro-Blebbistatin  Chemical Structure
  9. GC49736 10-acetyl Docetaxel 10-acetyl Docetaxel (10-Acetyl docetaxel) is an analog of Docetaxel, with anticancer activity. Docetaxel is a microtubule disassembly inhibitor, with antimitotic activity. 10-acetyl Docetaxel  Chemical Structure
  10. GC41110 16-epi Latrunculin B 16-epi Latrunculin B, first isolated from the Red Sea sponge N. 16-epi Latrunculin B  Chemical Structure
  11. GC48423 19-O-Acetylchaetoglobosin A A fungal metabolite with actin polymerization inhibitory and cytotoxic activities 19-O-Acetylchaetoglobosin A  Chemical Structure
  12. GC52029 2-Aminoflubendazole 2-Aminoflubendazole  Chemical Structure
  13. GC49244 4-oxo Isotretinoin An active metabolite of isotretinoin 4-oxo Isotretinoin  Chemical Structure
  14. GC48721 6-O-Demethyl Griseofulvin A metabolite of griseofulvin 6-O-Demethyl Griseofulvin  Chemical Structure
  15. GC40844 9-(2,2-Dicyanovinyl)julolidine 9-(2,2-Dicyanovinyl)julolidine (9-(2,2-Dicyanovinyl)julolidine), a molecular rotor and unique fluorescent dye, binds to tubulin and actin, and increases its fluorescence intensity drastically upon polymerization. 9-(2,2-Dicyanovinyl)julolidine  Chemical Structure
  16. GC25025 Abraxane Abraxane (Nab-Paclitaxel), a novel solvent-free taxane with the binding ratio of Paclitaxel to human serum albumin of 1:9, is an anti-microtubule drug that promotes microtubule aggregation in tubulin dimer and inhibits microtubule depolymerization to stabilize the microtubule system. Abraxane  Chemical Structure
  17. GC18274 Amiprofos-methyl Amiprofos-methyl (APM) is a phosphoric amide herbicide. Amiprofos-methyl  Chemical Structure
  18. GC25075 Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222) Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222, Antibiotic C 15003P3) is a potent inhibitor of tubulin polymerization with IC50 of 3.4 μM. Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222)  Chemical Structure
  19. GC42933 Binucleine 2 Binucleine 2 is an isoform-specific and ATP-competitive inhibitor of Drosophila Aurora B kinase (Ki = 0.36 μM), a kinase involved in cell division. Binucleine 2  Chemical Structure
  20. GC18408 BML-278 BML-278 is an activator of sirtuin 1 (SIRT1) that has an EC150 value (effective concentration able to increase the enzyme by 150%) of 1 uM. BML-278  Chemical Structure
  21. GC46946 BPC 157 (acetate) A pentadecapeptide with diverse biological activities BPC 157 (acetate)  Chemical Structure
  22. GC45395 Cabazitaxel-d9 Cabazitaxel-d9 is deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. Cabazitaxel-d9  Chemical Structure
  23. GC43135 Cambendazol Cambendazol is one of the most effective agents for the therapy of human strongyloidiasis and . Cambendazol  Chemical Structure
  24. GC40890 CAY10701 CAY10701 is a 7-deazahypoxanthine analog that prevents microtubule formation, blocking the proliferation of HeLa and MCF-7 cells (GI50s = 22 and 38 nM, respectively). CAY10701  Chemical Structure
  25. GC52367 Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide A biotinylated and citrullinated mutant vimentin peptide Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide  Chemical Structure
  26. GC52370 Citrullinated Vimentin (R144) (139-159)-biotin Peptide A biotinylated and citrullinated vimentin peptide Citrullinated Vimentin (R144) (139-159)-biotin Peptide  Chemical Structure
  27. GC40664 Colcemid

    Colcemid is a cytoskeletal inhibitor that induces mitotic arrest in the G2/M phase or meiotic arrest in the vesicle rupture (GVBD) phase in mammalian cells or oocytes, respectively.

    Colcemid  Chemical Structure
  28. GC47117 Colchicine-d6

    An internal standard for the quantification of colchicine

    Colchicine-d6  Chemical Structure
  29. GC49913 Davunetide (acetate) A neuroprotective ADNP-derived peptide Davunetide (acetate)  Chemical Structure
  30. GC43469 Diminutol Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. Diminutol  Chemical Structure
  31. GC48968 Docetaxel (hydrate)

    An analog of taxol with antitumor properties

    Docetaxel (hydrate)  Chemical Structure
  32. GC47250 Docetaxel-d9

    An internal standard for the quantification of docetaxel

    Docetaxel-d9  Chemical Structure
  33. GC49124 EN219 EN219 is a moderately selective synthetic covalent ligand against an N-terminal cysteine (C8) of RNF114 with an IC50 of 470 nM. EN219 inhibits RNF114-mediated autoubiquitination and p21 ubiquitination. EN219  Chemical Structure
  34. GC48720 Griseofulvic Acid A metabolite of griseofulvin Griseofulvic Acid  Chemical Structure
  35. GC48688 Griseofulvin-d3 An internal standard for the quantification of griseofulvin Griseofulvin-d3  Chemical Structure
  36. GC40048 MPS1/TTK Inhibitor MPS1/TTK inhibitor is an inhibitor of monopolar spindle 1 (MPS1/TTK; IC50 = 5.8 nM), a kinase involved in mitotic spindle checkpoint signaling that is overexpressed in certain cancerous tumors. MPS1/TTK Inhibitor  Chemical Structure
  37. GC41564 MPT0B014 An inhibitor of tubulin polymerization MPT0B014  Chemical Structure
  38. GC18445 N-Deacetylcolchicine An inhibitor of microtubule polymerization N-Deacetylcolchicine  Chemical Structure
  39. GC49404 Paclitaxel C A taxoid and an inhibitor of microtubule depolymerization Paclitaxel C  Chemical Structure
  40. GC45944 para-amino-Blebbistatin A more stable and less phototoxic form of (–)-blebbistatin with enhanced water solubility para-amino-Blebbistatin  Chemical Structure
  41. GC44618 Phalloidin-AMCA Conjugate Phalloidin-AMCA conjugate is a blue fluorophore that specifically labels filamentous actin (F-actin). Phalloidin-AMCA Conjugate  Chemical Structure
  42. GC44620 Phalloidin-Tetramethylrhodamine Conjugate Phalloidin-retramethylrhodamine conjugate is an orange fluorescent probe (ex/em = 546/575 nm) that selectively binds to F-actin. Phalloidin-Tetramethylrhodamine Conjugate  Chemical Structure
  43. GC48394 Phomopsinamine An inhibitor of microtubule polymerization Phomopsinamine  Chemical Structure
  44. GC49077 Podophyllotoxin-d6 An internal standard for the quantification of podophyllotoxin and picropodophyllotoxin Podophyllotoxin-d6  Chemical Structure
  45. GC44800 Quininib A CysLT1 and CysLT2 receptor antagonist Quininib  Chemical Structure
  46. GC45688 STX140 An estrogen sulfamate STX140  Chemical Structure
  47. GC48119 Suprafenacine An inhibitor of tubulin polymerization with anticancer activity Suprafenacine  Chemical Structure
  48. GC44976 Swinholide A

    Swinholide A is a natural dimeric dilactone macrolide toxin that causes actin depolymerization in cells.

    Swinholide A  Chemical Structure
  49. GC45750 Thymosin β4 (human, mouse, rat, porcine, bovine) (acetate) An actin-sequestering peptide Thymosin β4 (human, mouse, rat, porcine, bovine) (acetate)  Chemical Structure
  50. GC18763 TN-16 TN-16 is an inhibitor of microtubule polymerization (IC50 = 0.4-1.7 uM). TN-16  Chemical Structure
  51. GC52364 Vimentin (139-159)-biotin Peptide A biotinylated vimentin peptide Vimentin (139-159)-biotin Peptide  Chemical Structure
  52. GC52371 Vimentin (G146R) (139-159)-biotin Peptide A biotinylated mutant vimentin peptide Vimentin (G146R) (139-159)-biotin Peptide  Chemical Structure
  53. GC45595 Vulpinic Acid   Vulpinic Acid  Chemical Structure
  54. GC18578 YK-3-237 An inhibitor of tubulin polymerization and activator of SIRT1 YK-3-237  Chemical Structure

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