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Haspin

Haspin is a serine/threonine-protein kinase that phosphorylates H3T3ph (histone H3 at 'Ser-3') during mitosis. It is essential for the proper cohesion, mataphase aligment and normal cell cycle progression at mitotic centromeres.

Products for  Haspin

  1. Cat.No. Product Name Information
  2. GC50145 CHR 6494 trifluoroacetate CHR 6494 trifluoroacetate is a potent inhibitor of haspin, with an IC50 of 2 nM. CHR 6494 trifluoroacetate inhibits histone H3T3 phosphorylation. CHR 6494 trifluoroacetate induces the apoptosis of cancer cells, including melanoma and breast cancer. CHR 6494 trifluoroacetate can be used in the research of cancer. CHR 6494 trifluoroacetate  Chemical Structure
  3. GC17254 CHR-6494 A selective Haspin protein kinase inhibitor CHR-6494  Chemical Structure
  4. GC33086 LDN-192960 LDN-192960 is an inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50s of 10 nM and 48 nM, respectively. LDN-192960  Chemical Structure
  5. GC44047 LDN-192960 (hydrochloride) LDN-192960 is an inhibitor of haspin protein kinase and dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2) with IC50 values of 10 and 48 nM, respectively. LDN-192960 (hydrochloride)  Chemical Structure
  6. GC38403 LDN-192960 hydrochloride LDN-192960 hydrochloride is an inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50s of 10 nM and 48 nM, respectively. LDN-192960 hydrochloride  Chemical Structure

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