DNA Alkylating
DNA alkylating is the transfer of alkyl groups to particular bases, resulting in alkylation products such as O2‐alkylthymine and O6‐methylguanine that lead to DNA mutations.
Products for DNA Alkylating
- Cat.No. Product Name Information
- GC49470 1-Ethyl-1-nitrosourea (hydrate) A DNA alkylating agent
- GC52129 3-Amino-5-hydroxybenzoic Acid
- GC14564 Altretamine Antineoplastic agent
- GC13671 Busulfan DNA alkylating agent
- GC15793 Carmustine cell-cycle phase nonspecific alkylating antineoplastic agent
- GC47167 Dacarbazine-d6 An internal standard for the quantification of dacarbazine
- GC18100 Illudin S potent antitumor sesquiterpene
- GC41384 K-TMZ K-TMZ is a DNA alkylating agent.
- GC17865 Lomustine Antineoplastic drug
- GC44243 Monohydroxy Melphalan (hydrochloride) Monohydroxy melphalan is a DNA alkylating agent and a degradation product of melphalan.
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GC44251
MTIC
MTIC is a DNA alkylating agent, an active metabolite of dacarbazine, and an active degradation product of temozolomide.
- GC44348 N-desmethyl Bendamustine N-desmethyl Bendamustine is an active metabolite of the DNA alkylating agent bendamustine.
- GC14762 Palifosfamide An active metabolite of ifosfamide
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GC13667
Temozolomide
Temozolomide is an oral activity alkylating agent that induces the formation of O6-methylguanine in DNA
- GC52076 Temozolomide Acid Temozolomide Acid is a carboxylic acid derivative of Temozolomide. Temozolomide is a DNA alkylating agent, methylating the guanine and adenine bases of DNA, causing breaks in DNA double strand, cell cycle arrest, and eventually cell death. Temozolomide Acid has an activity similar to the parent compound Temozolomide with the same anticancer activity.
- GC16158 Thio-TEPA alkylating agent used to treat cancer
- GC15043 Trioxsalen intercalates into DNA and forms DNA single-strand adducts and interstrand crosslinks when activated with ultraviolet light