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Home >> Signaling Pathways >> DNA Damage/DNA Repair >> DNA Alkylating

DNA Alkylating

DNA alkylating is the transfer of alkyl groups to particular bases, resulting in alkylation products such as O2‐alkylthymine and O6‐methylguanine that lead to DNA mutations.

Products for  DNA Alkylating

  1. Cat.No. Product Name Information
  2. GC49470 1-Ethyl-1-nitrosourea (hydrate) A DNA alkylating agent 1-Ethyl-1-nitrosourea (hydrate) Chemical Structure
  3. GC52129 3-Amino-5-hydroxybenzoic Acid 3-Amino-5-hydroxybenzoic Acid Chemical Structure
  4. GC14564 Altretamine Antineoplastic agent Altretamine Chemical Structure
  5. GC13671 Busulfan DNA alkylating agent Busulfan Chemical Structure
  6. GC15793 Carmustine cell-cycle phase nonspecific alkylating antineoplastic agent Carmustine Chemical Structure
  7. GC47167 Dacarbazine-d6 An internal standard for the quantification of dacarbazine Dacarbazine-d6 Chemical Structure
  8. GC18100 Illudin S potent antitumor sesquiterpene Illudin S Chemical Structure
  9. GC41384 K-TMZ K-TMZ is a DNA alkylating agent. K-TMZ Chemical Structure
  10. GC17865 Lomustine Antineoplastic drug Lomustine Chemical Structure
  11. GC44243 Monohydroxy Melphalan (hydrochloride) Monohydroxy melphalan is a DNA alkylating agent and a degradation product of melphalan. Monohydroxy Melphalan (hydrochloride) Chemical Structure
  12. GC44251 MTIC

    MTIC is a DNA alkylating agent, an active metabolite of dacarbazine, and an active degradation product of temozolomide.

     MTIC Chemical Structure
  13. GC44348 N-desmethyl Bendamustine N-desmethyl Bendamustine is an active metabolite of the DNA alkylating agent bendamustine. N-desmethyl Bendamustine Chemical Structure
  14. GC14762 Palifosfamide An active metabolite of ifosfamide Palifosfamide Chemical Structure
  15. GC13667 Temozolomide

    Temozolomide is an oral activity alkylating agent that induces the formation of O6-methylguanine in DNA

     Temozolomide Chemical Structure
  16. GC52076 Temozolomide Acid Temozolomide Acid is a carboxylic acid derivative of Temozolomide. Temozolomide is a DNA alkylating agent, methylating the guanine and adenine bases of DNA, causing breaks in DNA double strand, cell cycle arrest, and eventually cell death. Temozolomide Acid has an activity similar to the parent compound Temozolomide with the same anticancer activity. Temozolomide Acid Chemical Structure
  17. GC16158 Thio-TEPA alkylating agent used to treat cancer Thio-TEPA Chemical Structure
  18. GC15043 Trioxsalen intercalates into DNA and forms DNA single-strand adducts and interstrand crosslinks when activated with ultraviolet light Trioxsalen Chemical Structure

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