Adenosine Receptor
Adenosine receptor (P1 receptors) is a class of purinergic receptors, G protein-coupled receptors with adenosine as endogenous ligand.
Products for Adenosine Receptor
- Cat.No. Product Name Information
- GC17413 (±)-5'-Chloro-5'-deoxy-ENBA adenosine A1 receptor agonist, selective and high-affinity
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GC10600
1,3-Dipropyl-8-phenylxanthine
A1 adenosine antagonist
- GC11112 2'-MeCCPA A1 adenosine receptor agonist
- GC10116 2-chloro-3-Deazaadenosine adenosine receptors agonist
- GC11665 2-Chloro-N6-cyclopentyladenosine adenosine A1 receptor agonist, potent and selective
- GC15111 2-Chloroadenosine adenosine receptor agonist
- GC17503 2-Cl-IB-MECA 2-Cl-IB-MECA (CF-102) is a selective A3 adenosine receptor (A3AR) agonist (Ki=0.33 nM). 2-Cl-IB-MECA displays 2500- and 1400-fold selectivity over A1 and A2A receptors respectively.
- GC11002 5'-(N-Cyclopropyl)carboxamidoadenosine adenosine A2 receptor agonist
- GC11199 8-(3-Chlorostyryl)caffeine 8-(3-Chlorostyryl)caffeine is a selective adenosine A2A receptor antagonist.
-
GC13274
8-Aminoadenine
Adenine receptor agonist
- GC50354 8-Cyclopentyl-1,3-dimethylxanthine High affinity adenosine A1 receptor antagonist
- GC30918 A2A receptor antagonist 1 A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both adenosine A2A receptor and A1 receptor with Ki values of 4 and 264 nM, respectively.
- GC30987 A2AR-agonist-1 An agonist of adenosine A2A receptor and inhibitor of ENT1
- GC38104 A2aR/A2bR antagonist-1 A2aR/A2bR antagonist-1 is an orally bioavailable, selective dual adenosine receptor (A2aR/A2bR) antagonist.
- GC31974 A2B receptor antagonist 1 A2B receptor antagonist 1 is a potent A2B adenosine receptor antagonist extracted from patent WO 2009157938 A1 EXAMPLE 9B.
- GC62820 A2B receptor antagonist 2 A2B receptor antagonist 2 (compound 18) is an adenosine receptor A2B antagonist, with Ki values of 2.30 μM, 6.8 μM and 3.44 μM for rA1, rA2A and hA2B, respectively.
- GC30993 AB-MECA AB-MECA is a high affinity A3 adenosine receptor agonist, has high affinity for recombinant A1 and A3 receptors.
- GC34143 Acefylline (Theophyllineacetic acid) Acefylline (Theophyllineacetic acid) (Theophyllineacetic acid), a xanthine derivative, is an adenosine receptor antagonist. Acefylline (Theophyllineacetic acid) is a peptidylarginine deiminase (PAD) activator. Acefylline (Theophyllineacetic acid) is also a bronchodilator, which inhibits rat lung cAMP phosphodiesterase isoenzymes.
- GC19630 Adenosine 2′-monophosphate Adenosine 2′-monophosphate (2'-AMP) is converted by extracellular 2',3'-CAMP.
- GC35248 Adenosine 5'-monophosphate monohydrate Adenosine 5'-monophosphate monohydrate is an adenosine A1 receptor agonist.
- GC38733 Adenosine A1 receptor activator T62 Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor.
- GC38884 Adenosine amine congener An adenosine A1 receptor agonist
- GC35249 Adenosine antagonist-1 Adenosine antagonist-1 is an adenosine A3 receptor (AA3R) antagonist.
- GC65901 Adenosine receptor antagonist 2 Adenosine receptor antagonist 2 is an orally active A2a/A2b adenosine receptor antagonist with IC50s of 1 nM and 3 nM, respectively. Adenosine receptor antagonist 2 has anti-tumor activity.
- GC66007 Adenosine receptor antagonist 3 Adenosine receptor antagonist 3 is a potent antagonist of adenosine receptor. Adenosine receptor antagonist 3 has the potential for the research of cancer disease (extracted from patent WO2019233994A1, compound 1).
- GC25051 Alloxazine Alloxazine (Isoalloxazine) is an A2 receptor antagonist, which is approximately 10-fold more selective for the A2B receptor than for the A2A receptor.
- GC16159 ANR 94 Adenosine A2A-R antagonist
- GC33702 APNEA (N6-[2-(4-Aminophenyl)ethyl]adenosine) APNEA (N6-[2-(4-Aminophenyl)ethyl]adenosine) (N6-[2-(4-Aminophenyl)ethyl]adenosine) is a potent, non-selective A3 adenosine receptor agonist.
- GC38887 Arotinolol Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker.
- GC19049 AZD4635 AZD4635 (HTL1071) is a potent, selective and orally active adenosine A2A receptor (A2AR) antagonist. AZD4635 binds to human A2AR with a Ki of 1.7 nM and shows >30-fold selectivity over other adenosine receptors.
- GC18114 BAY 60-6583 Potent A2B receptor agonist
-
GC19502
BAY-545
BAY-545 is a potent and selective A2B adenosine receptor antagonist
- GC64647 Binodenoson Binodenoson (MRE-0470) is a potent and selective A2A adenosine receptor agonist (KD=270 nM).
- GC14935 Capadenoson A partial adenosine receptor agonist
- GC14674 CGH 2466 dihydrochloride adenosine receptor antagonist
- GC10070 CGS 15943 adenosine receptor antagonist
- GC10172 CGS 21680 A selective agonist of the adenosine A2A receptor
- GC11978 CGS 21680 HCl CGS 21680 HCl is a selective adenosine A2A receptor agonist with a Ki of 27 nM.
- GC32734 CPI-444 (V81444) CPI-444 (V81444) (V81444) is a potent, orally active and selective adenosine A2A receptor (A2AR) antagonist, which induces antitumor responses.
- GC14706 CV 1808 Adenosine A2 receptor agonist
- GC13444 Doxofylline PDE inhibitor
- GC16099 DPCPX A1 adenosine receptor antagonist
- GC13652 Dyphylline An adenosine receptor antagonist and phosphodiesterase inhibitor
- GC32675 GP531 GP531 is a potent, second-generation adenosine regulating agent, is pharmacologically silent under basal conditions but increases localized endogenous adenosine during ischemia.
- GC12315 GR 79236 adenosine A1 receptor agonist
- GC38789 GS-6201 An adenosine A2B receptor antagonist
- GC11493 HEMADO adenosine A3 receptor agonist
- GC19197 IB-MECA IB-MECA (IB-MECA) is a first-in-class, orally active and selective A3 adenosine receptor (A3AR) agonist.
- GC63022 Inupadenant Inupadenant is an orally active, highly selective A2A receptor antagonist. Inupadenant is not brain-penetrant. Inupadenant has potent anti-tumor activity.
- GC50679 ISAM 140 ISAM 140 (22b) is a potent and highly selective A2B adenosine receptor antagonist with a Ki of 3.49 nM.
- GC11590 Istradefylline(KW-6002) Istradefylline(KW-6002) is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease.
- GC31217 KF21213 KF21213 is a highly selective ligand for mapping CNS adenosine A2A receptors.
- GC31264 KFM19 KFM19 is a potent, selective Adenosine receptor (A1-receptor) antagonist, with an IC50 of 50 nM.
- GC50571 KI-7 Positive allosteric modulator of A2B receptors
- GC12417 KW 3902 KW 3902 (KW-3902) is a potent, selective adenosine A1 receptor antagonist that is under development for the treatment of patients with acute congestive heart failure and renal impairment.
- GC33871 LAS101057 A potent adenosine A2B receptor antagonist
- GC17499 Lu AA 47070 adenosine A2A receptor antagonist
- GC11851 LUF 5834 A2A and A2B adenosine receptor partial agonist
- GC15986 LUF6000 A positive allosteric modulator of adenosine A3 receptors
- GC61872 LUF6096 LUF6096, a potent allosteric enhancer of the adenosine A3 receptor, is able to allosterically enhance agonist binding.
- GC63304 MIPS521 MIPS521 is a positive allosteric modulator of adenosine A1 receptor (A1AR).
- GC12584 MRE 3008F20 adenosine A3 receptor antagonist
- GC11579 MRS 1220 human A3 adenosine receptor antagonist
- GC10202 MRS 1334 antagonist for the human adenosine A3 receptor
- GC10320 MRS 1706 adenosine A2B receptor inverse agonist
-
GC13807
MRS 1754
adenosine A2B receptor antagonist
- GC13021 MRS 3777 hemioxalate adenosine A3 receptor antagonist
- GC50162 MRS 5698 High affinity and selective A3 agonist
- GC38112 MRS-1191 MRS-1191 is a potent and selective A3 adenosine receptor antagonist with a KB value of 92 nM, a Ki value of 31.4 nM for human A3 receptor and an IC50 of 120 nM for CHO cells.
- GC33652 MRS1177 MRS1177 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 0.3 nM.
- GC33654 MRS1186 MRS1186 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 7.66 nM.
- GC14078 MRS1523 adenosine A3 receptor antagonist
- GC30739 N-0861 racemate N-0861 racemate is the racemate of N-0861.
- GC36676 N-[(4-Aminophenyl)methyl]adenosine N-[(4-Aminophenyl)methyl]adenosine is a adenosine receptor inhibitor, with Ki of 29 nM for Rat ecto-5′-Nucleotidase.
- GC36679 N6-(2-Phenylethyl)adenosine N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine), an adenosine derivative, is a potent adenosine receptors (AR) agonist with Ki values of 11.8 nM, 30.1 nM, 0.63 nM for rat A1AR, human A1AR and hA3AR, respectively.
- GC33667 N6-Cyclohexyladenosine (CHA) N6-Cyclohexyladenosine (CHA) is a selective A1 receptor agonist (EC50 = 8.2 nM).
-
GC14369
N6-Cyclopentyladenosine
adenosine A1 receptor agonist
- GC34921 N6-Ethyladenosine An adenosine A1 and A3 receptor agonist
- GC15304 NECA NECA (NECA) is a nonselective adenosine receptor agonist.
- GC16141 Nicergoline vasodilator
- GN10652 Norisoboldine
- GC30916 PD 117519 (CI947) PD 117519 (CI947) (CI947) is an A2A adenosine agonist which has shown oral antihypertensive activity in pharmacological animal models.
- GC10103 PD 81723 Allosteric potentiator at the adenosine A1 receptor
- GC12200 Pentostatin A purine antimetabolite and an ADA inhibitor
- GC11591 Preladenant An adenosine A2A receptor antagonist
- GC10475 Proxyphylline A1 adenosine receptor antagonist
- GC14863 PSB 0777 ammonium salt adenosine A2A receptor full agonist
- GC17844 PSB 0788 adenosine A2B receptor antagonist
- GC12542 PSB 10 hydrochloride human adenosine A3 receptor antagonist
- GC14702 PSB 11 hydrochloride human adenosine A3 receptor antagonist
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GC17756
PSB 1115
human A2B adenosine receptor antagonist
-
GC10584
PSB 36
A1 adenosine receptor antagonist
- GC13153 PSB 603 Adenosine A2B receptor antagonist
- GC13082 Regadenoson Highly selective and low affinity A2A adenosine agonist
- GC12328 SCH 442416 adenosine A2A receptor antagonist
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GC14565
SCH 58261
A2A adenosine receptor competitive antagonist
-
GC31246
Sch412348
Sch412348 is a potent competitive antagonist of the human adenosine A2A receptor (Ki=0.6 nM) and has >1000-fold selectivity over all other adenosine receptors.
- GC14198 SDZ WAG 994 A1 adenosine receptor agonist
-
GC69893
Sipagladenant
Sipagladenant (Compound I) is an orally active adenosine receptor A2A inverse agonist that can be used for the study of frontal lobe dysfunction.
- GC14290 SLV 320 SLV 320 (SLV 320) is a potent, selective and orally active adenosine A1 receptor antagonist, with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2A receptors respectively.