Cannabinoid Receptor
The cannabinoid receptor (CB1 and CB2) is a member of G-protein coupled receptor which plays a significant role in physiologic processes such as cognitive and immune functions.
Products for Cannabinoid Receptor
- Cat.No. Product Name Information
- GC10907 (±)-SLV 319 (±)-SLV 319 ((±)-SLV319) is the racemate of SLV319.
- GC10028 (R)-SLV 319 CB1 receptor antagonist
- GC63410 (Rac)-MRI-1867 (Rac)-MRI-1867 ((Rac)-MRI-1867, compound 6b) is a cannabinoid receptor type 1 (CB1R)/iNOS antagonist, with a Ki of 5.7 nM for CB1R.
- GC10753 (S)-SLV 319 (S)-SLV 319 (SLV319) is a potent, selective and orally active antagonist of cannabinoid CB1 receptor, with a Ki of 7.8 nM.
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GC16403
2-Arachidonoyl Glycerol
An endogenous agonist of the cannabinoid (CB) receptors CB1 and CB2
- GC16196 2-Palmitoylglycerol Endogenous fatty acid glycerol ester
- GC17100 4-Quinolone-3-Carboxamide CB2 Ligand ligand of the CB2 receptor
- GC15850 4-Quinolone-3-Carboxamide Furan CB2 Agonist 4-Quinolone-3-Carboxamide Furan CB2 Agonist is a potent and selective agonist for the CB2 (cannabinoid type 2) receptor with a Ki of 8.5 nM.
- GC18199 A-836339 A-836339 is a synthetic cannabinoid (CB) which has a higher affinity for the peripheral CB2 receptor (Ki = 0.64 nM) over the central CB1 receptor (Ki = 270 nM).
- GC16480 AM 281 A CB1 antagonist
- GC62835 AM-6538 AM6538 is a long-acting, high affinity and pseudo-irreversible cannabinoid (CB) antagonist.
- GC15414 AM1241 Cannabinoid CB2 receptor agonist,potent and selective
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GC15717
AM251
A potent CB1 antagonist
- GC15093 AM4113 AM4113 is caimabinoid 1 (CB1) antagonist extracted from patent WO2016184310A1, compound 3, inhibits CB1 in vivo with an IC50 of 25.5 nM.
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GC10147
AM630
An inverse agonist at CB2 and partial agonist at CB1 receptors
- GC14661 AM6545 CB1 selective neutral antagonist
- GC35339 Anandamide An immune modulator in the central nervous system
- GC18435 Arachidonoyl 2'-Chloroethylamide A potent and selective CB1 receptor agonist
- GC16826 Arachidonoyl amide CB1 receptor agonist
- GC18097 Arachidonoyl Serinol CB1 receptor agonist
- GC11849 Arachidonyl serotonin Arachidonyl serotonin (Arachidonyl serotonin; AA-5-HT) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC50 value of 1~12 μM.
- GC10205 Arvanil Cannabinoid CB1 and vanilloid TRPV1 (VR1) agonist
- GC14115 AVE-1625 AVE-1625 (AVE1625) is an orally active CB1 receptor antagonist.
- GC62855 AZD1940 AZD1940 is an orally active, high affinity cannabinoid CB1/CB2 receptor agonist with pKi values of 7.93 and 9.06 for human CB1R and CB2R, respectively.
- GC61778 BAY 38-7271 BAY 38-7271 is selective and highly potent and cannabinoid CB1/CB2 receptor agonist, with Kis of 1.85 nM and 5.96 nM for recombinant human CB1 receptor and CB2 receptor, respectively.
- GC19060 Bay 59-3074 Bay 59-3074 is a novel, selective CB1/CB2 receptor partial agonist with Ki values of 48.3 and 45.5 nM at human CB1 and CB2 receptors respectively .
- GC11376 BML-190 CB2 receptor ligand
- GC66030 CB1 agonist 1 CB1 agonist 1 (compound 22) is an agonist of CB1. CB1 agonist 1 shows affinity to CB1 receptor with an pIC50 value of 5.7. CB1 agonist 1 can be used for the research of brain disorders.
- GC31306 CB1 antagonist 1 CB1 antagonist 1 is an antagonist of CB1 receptor, used in the research of metabolic syndrome and obesity, neuroinflammatory disorders, cognitive disorders and psychosis, gastrointestinal disorders, and cardiovascular conditions.
- GC30935 CB1-IN-1 CB1-IN-1 (BPRCB1184) is a peripherally restricted CB1R antagonist, with Ki of 0.3 nM and 21 nM for CB1R (EC50 = 3 nM) and CB2R, respectively.
- GC33756 CB2R-IN-1 CB2R-IN-1 is a potent cannabinoid CB2 receptor inverse agonist with a Ki of 0.9 nM.
- GC18110 COR 170 inverse agonist of CB2 receptors
- GC17205 CP-945598 HCl CP-945598 HCl is a potent and selective cannabinoid receptor CB1 antagonist with Ki of 0.7 nM, exhibits 10,000-fold greater selectivity against human CB2 receptor.
- GC50579 Ec2la Ec2la is an orally active cannabinoid type-2 receptors (CB2Rs) positive allosteric modulator.
- GC11760 GW842166X Cannabinoid receptor agonist
- GC17133 Hemopressin (human, mouse) CB1 receptor inverse agonist; endogenous peptide substrate for endopeptidase 24.15 (ep24.15), neurolysin (ep24.16) and ACE
- GC17116 Hemopressin (rat) selective CB1 receptor inverse agonist
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GC13965
HU 308
CB2-receptor agonist
- GC13660 JD5037 inverse agonist at CB1 receptors
- GC16644 JTE 907 cannabinoid CB2 receptor inverse agonist
- GC10885 JWH 133 An Analytical Reference Standard
- GC18496 Leelamine (hydrochloride) Leelamine is a diterpene molecule whose name derives from the Sanskrit word leela which means 'play'- It has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 uM.
- GC50273 LEI 101 hydrochloride Potent and selective CB2 partial agonist; orally biovailable
- GC12538 LH 21 silent CB1 antagonist
- GC13318 LY 320135 CB1 receptor antagonist/inverse agonist
- GC19231 LY2828360 LY2828360 is a slowly acting but efficacious G protein-biased cannabinoid (CB2) agonist, inhibiting cAMP accumulation and activating ERK1/2 signaling.
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GC12420
MAFP
cPLA2 and iPLA2 inhibitor, potent FAAH inhibitor
- GC36579 MDA 19
- GC15788 MJ 15 CB1 receptor antagonist
- GC11453 ML-191 inhibitor of LPI-induced phosphorylation of ERK1/2
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GC14626
MM-22
biotinylated anandamide analog acts as a probe for visualizing the accumulation and intracellular trafficking of anandamide
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GC14750
N-Arachidonylglycine
Endogenous anandamide-like compound
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GC31536
N-Oleoyl glycine
A putative substrate for peptidyl glycine αamidating enzyme
- GC18041 NESS 0327 extremely potent cannabinoid (CB) receptor antagonist
- GC13267 NIDA 41020 CB1 receptor antagonist
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GC69562
Nimacimab
Nimacimab (RYI-018) is a negative allosteric modulating monoclonal antibody that targets the CB1 receptor. Nimacimab can be used in research on metabolic diseases.
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GC17699
O-1821
cannabidiol analog with close structural similarity to O-1918 which is a selective antagonist of abnormal cannabidiol
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GC13847
O-1918
endothelial anandamide receptor antagonist
- GC16651 O-2050 high affinity cannabinoid CB1 receptor silent antagonist
- GC14042 Oleamide CB1 cannabinoid receptor agonist
- GC30966 Olivetol Olivetol is a naturally phenol found in lichens and produced by certain insects, acting as a competitive inhibitor of the cannabinoid receptors CB1 and CB2.
- GC30504 Olorinab (APD 371) Olorinab (APD 371) (APD 371) is a highly potent, selective and fully efficacious cannabinoid receptor type 2 (CB2) agonist, with an EC50 of 6.2 nM for hCB2.
- GC10664 Org 27569 Cannabinoid CB1 receptor allosteric modulator
- GC10843 Otenabant
- GC16548 Palmitoylisopropylamide FAAH inhibitor
- GC14461 PB-22 Synthetic cannabinoid
- GC16171 PF 514273 CB1 receptor antagonist
- GC50387 PM 226 Potent and selective CB2 receptor agonist; BBB permeable; neuroprotective
- GC12920 Pregnenolone steroid hormone
- GC36963 Pregnenolone monosulfate Pregnenolone monosulfate (3β-Hydroxy-5-pregnen-20-one monosulfate) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones.
- GC44680 Pregnenolone sulfate (sodium salt) Pregnenolone sulfate (sodium salt) (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones.
- GC65106 Pregnenolone-d4-1
- GC50435 PSB CB5 Selective GPR18 antagonist
- GC50143 PSNCBAM-1 Negative allosteric modulator of CB1 receptors
- GC14177 R-1 Methanandamide Phosphate CB1 receptor agonist
- GC13190 R-Palmitoyl-(1-methyl) Ethanolamide synthetic analog of palmitoyl ethanolamide (PEA)
- GC17259 Rimonabant CB1 receptor antagonist
- GC16466 Rimonabant hydrochloride A potent and selective CB1 receptor antagonist
- GC63617 RTICBM-189 RTICBM-189 is a potent, brain-penetrant allosteric modulator of the cannabinoid type-1 (CB1) receptor with a pIC50 of 7.54 in Ca2+ mobilization assay.
- GC66413 RVD-Hpα TFA RVD-Hpα TFA is the N-terminally extended form of human hemopressin that acts as a selective CB1 receptor agonist. RVD-Hpα TFA increases intracellular Ca2+ levels in cells expressing CB1 receptors in vitro. RVD-Hpα TFA also high affinity CB2 positive allosteric modulator (Ki=50 nM).
- GC13605 S-1 Methanandamide CB1 receptor ligand
- GC12868 S-2 Methanandamide potent CB1 receptor agonist
- GC67972 S-777469
- GC50271 SCH 336 Highly potent and selective CB2 inverse agonist
- GC10032 SR 144528 CB2 receptor inverse agonist
- GC15574 Taranabant A CB1 receptor inverse agonist
- GC37737 Taranabant ((1R,2R)stereoisomer) Taranabant (1R,2R)stereoisomer is the R-enantiomer of Taranabant.
- GC37738 Taranabant racemate Taranabant racemate (MK-0364 racemate) is an antagonist and/or inverse agonist of the Cannabinoid-1 (CB1) receptor extracted from patent WO 2004048317 A1.
- GC10646 TC-C 14G CB1 receptor inverse agonist
- GC65277 Tedalinab Tedalinab (GRC-10693) is a potent, orally active, and selective cannabinoid receptor 2 (CB2) agonist.
- GC15327 Tetrahydromagnolol peripheral CB2 receptor agonist
- GC39666 TM38837 TM38837 is a peripheral selective cannabinoid receptor type 1 (CB1) receptor antagonist.
- GC12978 Tocrifluor T1117 Tocrifluor T1117 (T1117), a fluorescent form of the cannabinoid CB1 receptor antagonist AM251, is a selective fluorescent GPR55 ligand.
- GC37889 VCE-004.8 VCE-004.8 (VCE-004.8) is an orally active, specific PPARγ and CB2 receptor dual agonist.
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GC70118
Vicasinabin
Vicasinabin (RG7774) is an effective agonist of the cannabinoid receptor 2 (CB2). Vicasinabin has potential for researching human diseases, including chronic pain, atherosclerosis, bone regulation, neuroinflammation and other related conditions (information extracted from patent US20130116236A1).
- GC45150 Voacamine Voacamine is an alkaloid originally isolated from Voacanga that has diverse biological activities.
- GC37935 WIN 55,212-2 Mesylate A potent CB1 and CB2 receptor agonist
- GC31809 Yangonin An Analytical Reference Standard
- GC33681 β-Caryophyllene β-Caryophyllene is a CB2 receptor agonist.