Somatostatin Receptor
Somatostatin receptor is a G protein-coupled receptor that includes five known somatostatin receptors.
Products for Somatostatin Receptor
- Cat.No. Product Name Information
- GC16919 (1R,1'S,3'R/1R,1'R,3'S)-L-054,264 somatostatin sst2 receptor agonist
- GC64665 AGI-41998 AGI-41998 is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A).
- GC64635 AGI-43192 AGI-43192 is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A).
- GC62843 Angiopeptin TFA Angiopeptin TFA, a cyclic octapeptide analogue of somatostatin, is a weak sst2/sst5 receptor partial agonist with IC50 values of 0.26?nM and 6.92?nM, respectively.
- GC14119 BIM 23052 sst5 receptor agonist
- GC16400 BIM 23056 Somatostatin receptor ligand
- GC62381 BIM-23190 hydrochloride BIM-23190 hydrochloride, a somatostatin analog, a selective SSRT2 and SSRT5 agonist, exhibits Ki values of 0.34 nM and 11.1 nM for SSTR2 and SSTR5, respectively. BIM-23190 can be used in the study for cancer and acromegaly.
- GC13686 CH 275 Potent somatostatin receptor 1 (sst1) agonist
- GC12835 Cortistatin 14 Cortistatin 14 (CST-14, human, rat), a neuropeptide with neuronal depressant and sleep modulating properties, can bind to all five cloned somatostatin receptors (SSTRs) and ghrelin receptor to exert its biological activities and co-exists with GABA within the cortex and hippocampus.
- GC35730 Cortistatin-14 TFA Cortistatin-14 (TFA), a neuropeptide have structural similarity to somatostatin-14, binds and exerts its function via the somatostatin receptors (sst1-sst5).
- GC15495 Cyclosomatostatin somatostatin receptor antagonist
- GC14747 CYN 154806 somatostatin sst2 receptor antagonist
- GC35787 CYN 154806 TFA CYN 154806 TFA, a cyclic octapeptide, is a potent and selective somatostatin sst2 receptor antagonist, with pIC50 values of 8.58, 5.41, 6.07, 5.76 and 6.48 for human recombinant sst2, sst1, sst3, sst4 and sst5 receptors respectively.
- GC36358 J-2156 J-2156 is a high potent, selective somatostatin receptor type 4 (SST4 receptor) agonist with IC50s of 0.05 nM and 0.07 nM for human and rat SST4 receptors, respectively.
- GC61413 J-2156 TFA J-2156 TFA is a high potent, selective somatostatin receptor type 4 (SST4 receptor) agonist with IC50s of 0.05 nM and 0.07 nM for human and rat SST4 receptors, respectively.
- GC10181 L-803,087 trifluoroacetate L-803,087 trifluoroacetate is a potent and selective somatostatin sst4 receptor agonist with a Ki of 0.7 nM.
- GC17668 L-817,818 somatostatin sst5 receptor agonist
-
GC31349
MK-4256
MK-4256 is a potent and selective SSTR3 antagonist with IC50s of 0.66 nM and 0.36 nM in human and mouse receptor binding assays, respectively.
- GC12448 NNC 26-9100 Somatostatin sst4 receptor agonist
- GC10899 Octreotide acetate A somatostatin receptor agonist
- GC63137 Paltusotine Paltusotine (CRN00808) is an orally active, nonpeptide selective somatostatin type 2 (SST2) receptor agonist.
- GC10729 Pasireotide stable cyclohexapeptide somatostatin mimic
- GC62194 Pasireotide acetate Pasireotide (SOM230) acetate, a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively).
- GC36857 Pasireotide ditrifluoroacetate Pasireotide (SOM230) ditrifluoroacetate, a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively).
- GC36858 Pasireotide L-aspartate salt Pasireotide (SOM230) L-aspartate salt, a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively).
- GC13758 Seglitide sst2 and sst5 somatostatin receptors agonist
- GC16422 Somatostatin 1-28 Somatostatin receptor agonist
- GC65313 SSTR5 antagonist 1 SSTR5 antagonist 1 is a potent, selective, and orally available somatostatin receptor subtype 5 (SSTR5) antagonist with IC50s of 9.6 and 57 nM for hSSTR5 and mSSTR5, respectively.
- GC64259 SSTR5 antagonist 2 hydrochloride SSTR5 antagonist 2 hydrochloride is a highly potent, oral active and selective somatostatin (receptor) subtype 5 (SSTR5) antagonist and has potential for the research of type 2 diabetes mellitus (T2DM).
- GC50094 TC-G 1003 TC-G 1003 is a potent somatostatin receptor subtype 2 (sst2) agonist with a Ki value of 0.025 nM and a cAMP IC50 value of 4.8 nM.
- GC10328 TT 232 sst1/sst4 somatostatin receptors agonist
- GC34130 Vapreotide acetate (RC-160 acetate) Vapreotide acetate (RC-160 acetate) (RC-160 acetate; BMY-41606 acetate) is a neurokinin-1 (NK1) receptor antagonist, with an IC50 of 330 nM.