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Urotensin Receptor

Urotensin receptor (UT) is a G-protein coupled receptor which binds the peptide hormoneurotensin. The urotensin-II (UT) receptor is a Gq/11-protein-coupled receptor that mediates complex hemodynamic effects and influences neuromuscular physiology. The UT receptor displays greatest expression levels in the peripheral vasculature, heart and kidney, although they are found elsewhere, notably the central nervous system, at lower levels. The UT receptor produces potent but variable vasoconstrictor effects in some vascular beds, yet mediates vasodilation in others; it has also been implicated in osmoregulation.

Targets for  Urotensin Receptor

Products for  Urotensin Receptor

  1. Cat.No. Product Name Information
  2. GC17414 Palosuran Urotensin-II receptor antagonist Palosuran  Chemical Structure
  3. GC61546 Palosuran hydrochloride Palosuran hydrochloride (ACT-058362 hydrochloride) is a potent, selective, and orally active antagonist of urotensin II receptor, with an IC50 of 3.6 nM for CHO cell membranes expressing human recombinant receptors. Palosuran hydrochloride  Chemical Structure
  4. GC37871 Urotensin II (114-124), human TFA Urotensin II (114-124), human TFA, an 11-amino acid residue peptide, is a potent vasoconstrictor and agonist for the orphan receptor GPR14. Urotensin II (114-124), human TFA  Chemical Structure
  5. GC34236 Urotensin II, mouse Urotensin II, mouse is an endogenous ligand for the orphan G-protein-coupled receptor GPR14 or SENR. Urotensin II, mouse  Chemical Structure
  6. GC62225 Urotensin II, mouse acetate Urotensin II, mouse acetate is an endogenous ligand for the orphan G-protein-coupled receptor GPR14 or SENR. Urotensin II, mouse acetate  Chemical Structure
  7. GC39578 Urotensin II, mouse TFA Urotensin II, mouse TFA is an endogenous ligand for the orphan G-protein-coupled receptor GPR14 or SENR. Urotensin II, mouse TFA  Chemical Structure

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