Vasopressin Receptor
Vasopressin receptors are G-protein coupled receptors that mediate coagulation factor release, platelet aggregation, vasoconstriction, release of antidiuresis and ACTH release etc.
Products for Vasopressin Receptor
- Cat.No. Product Name Information
- GA20084 (Deamino-Cys¹,β-cyclohexyl-Ala⁴,Arg⁸)-Vasopressin Studies revealed that this specific vasopressin agonist exhibited a nanomolar affinity for V-1b receptors from various mammalian species (bovine, human, rat). It exhibited high V-1b/V-1a and V-1b/oxytocin selectivity for rat, human, and bovine receptors. Furthermore, it showed a high V-1b/V-2 specificity for both bovine and human vasopressin receptors. Therefore, d(Cha?)-AVP is a promising tool for research of V-1b receptor structure-function relationships.
- GC66678 2-(3-Trifluoromethylphenyl)glycine hydrochloride 2-(3-Trifluoromethylphenyl)glycine hydrochloride is a precursor of substituted 2-acetamido-5-aryl-l, 2,4-triazolones. Substituted 2-acetamido-5-aryl-l, 2,4-triazolones are dual V1a/V2 receptor antagonists and can be used in cardiovascular disease research.
- GC30764 Argipressin (Vasopressin) Argipressin (Vasopressin) (Arg8-vasopressin) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1.
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GC12194
Atosiban
mixed antagonist of oxytocin and vasopressin receptors
- GC39849 Atosiban acetate Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue.
- GC31295 Balovaptan (RG7314) Balovaptan (RG7314) (RG7314) is an orally available, selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors, and is used for the research of autism.
- GA20807 Big Endothelin-1 (1-38), human Big Endothelin-1 (1-38), human is the precursor of endothelin-1.
- GA20808 Big Endothelin-1 (1-39), porcine Big Endothelin-1 (1-39), porcine is the precursor of endothelin-1.
- GC12627 Conivaptan HCl Conivaptan (hydrochloride) is a non-peptide antagonist of vasopressin receptor, with Ki values of 0.48 and 3.04 nM for rat liver V1A receptor and rat kidney V2 receptor respectively.
- GC12303 Desmopressin A vasopressin receptor agonist
- GC11265 Desmopressin Acetate
- GC16591 d[Cha4]-AVP human vasopressin V1B receptor agonist
- GC15154 d[Leu4,Lys8]-VP Selective vasopressin V1B receptor agonist
- GC61959 D[LEU4,LYS8]-VP TFA D[LEU4,LYS8]-VP TFA is a selective agonist of vasopressin V1b receptor, with the Kis of 0.16 nM, 0.52 nM, and 0.1.38 nM for rat, human and mouse V1b receptor, respectively.
- GC65415 Felypressin acetate Felypressin acetate (PLV-2 acetate) is a non-catecholamine vasoconstrictor and a vasopressin 1 agonist.
- GC11991 L-371,257 human oxytocin (OT) receptor antagonist
- GC32453 Lixivaptan (VPA-985) Lixivaptan (VPA-985) (VPA-985, WAY-VPA 985) is an orally active and selective vasopressin receptor V2 antagonist, with IC50 values of 1.2 and 2.3 nM for human and rat V2, respectively.
- GC14880 Mozavaptan novel competitive vasopressin receptor antagonist
- GC44247 Mozavaptan (hydrochloride) Mozavaptan is a benzazepine derivative that antagonizes the binding of arginine vasopressin (AVP) to vasopressin receptors located in the liver (V1; IC50 = 1.2 μM) and kidney (V2; IC50 = 14 nM).
- GC10622 OPC 21268 OPC 21268 (OPC-21268) is an orally effective, nonpeptide, vasopressin V1 receptor antagonist with an IC50 of 0.4 μM.
- GC30890 RG7713 (RO5028442) RG7713 (RO5028442) (RO5028442) is a highly potent and selective Brain-Penetrant Vasopressin 1a (V1a) receptor antagonist with Kis of 1 nM (hV1a) and 39 nM (mV1a).
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GC69875
Selepressin acetate
Selepressin (FE 202158) acetate is a selective vasopressin V1A receptor agonist. Selepressin acetate is an effective vasoconstrictor and can be used in the research of septic shock.
- GC12462 SR 49059 vasopressin V1A receptor antagonist
- GC38948 SRX246 SRX246 is a potent, CNS-penetrant, highly selective, orally bioavailable vasopressin 1a (V1a) receptor antagonist (Ki=0.3 nM for human V1a).
- GC50376 SSR 149415 Potent and selective vasopressin V1B antagonist
- GC50246 TASP 0390325 Potent and selective V1B receptor antagonist; orally bioavailable
- GC32463 Terlipressin Terlipressin is a vasopressin analogue with potent vasoactive properties.
- GC39830 Terlipressin acetate A prodrug form of lysipressin
- GC15575 Tolvaptan AVP V2-receptor antagonist
- GC31475 WAY-151932 (VNA-932) WAY-151932 (VNA-932) is a vasopressin V2-receptor agonist with IC50 of 80.3 nM and 778 nM in human-V2 binding and V1a binding assay.