Adaptive Immunity
Products for Adaptive Immunity
- Cat.No. Product Name Information
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GC45194
α-(difluoromethyl)-DL-Arginine
Bacteria synthesize the cellular growth factor putrescine through a number of pathways.
- GC50708 (±)-ML 209 An RORγt antagonist
- GC41703 (E)-C-HDMAPP (ammonium salt) Synthetic and natural alkyl phosphates, also known as phosphoantigens, stimulate the proliferation of γδ-T lymphocytes.
- GC49028 (S)-3-Thienylglycine A thienyl-containing amino acid
- GC49768 1,1’-Ethylidene-bis-(L-tryptophan) A potential impurity found in commercial preparations of L-tryptophan
- GC40910 1-Oleoyl-2-hydroxy-sn-glycero-3-PE 1-Oleoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine.
- GC18376 1-Palmitoleoyl glycerol 1-Palmitoleoyl glycerol is a bioactive monoacylglycerol.
- GC42026 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC is an abundant gonadal LPC (lysophosphatidylcholine).
- GC45693 1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PC A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications
- GC46400 10(11)-Cl-BBQ Mixture A mixture that acts as an AhR agonist
- GC52343 113-O12B An ionizable cationic lipidoid
- GC46415 12-Bromododecanoic Acid A halogenated form of lauric acid
- GC49759 13C17-Mycophenolic Acid An internal standard for the quantification of mycophenolic acid
- GC18778 16,16-dimethyl Prostaglandin A1 16,16-dimethyl PGA1 is a metabolism resistant analog of PGA1.
- GC42112 2-Acetyl-5-tetrahydroxybutyl Imidazole Sphingosine-1-phosphate (S1P) lyase catalyzes the irreversible decomposition of S1P to hexadecanaldehyde and phosphoethanolamine.
- GC46553 2-Nonylquinolin-4(1H)-one A quinolone alkaloid with diverse biological activities
- GC52446 2-Nonylquinolin-4(1H)-one-d4 An internal standard for the quantification of 2-nonylquinolin-4(1H)-one
- GC46549 2F-Peracetyl-Fucose An inhibitor of protein fucosylation
- GC46583 3-Amino-2,6-Piperidinedione An active metabolite of (±)-thalidomide
- GC42259 3-Deaza-2'-deoxyadenosine 3-Deaza-2'-deoxyadenosine strongly inhibits lymphocyte-mediated cytolysis with low cytotoxicity when applied at 100 μM.
- GC49244 4-oxo Isotretinoin An active metabolite of isotretinoin
- GC49206 7α-hydroxy Dehydroepiandrosterone An active metabolite of dehydroepiandrosterone
- GC46740 7β,27-dihydroxy Cholesterol An oxysterol and agonist of RORγ and RORγt
- GC46733 7,12-Dimethylbenz[a]anthracene 7,12-Dimethylbenz[a]anthracene has carcinogenic activity as a polycyclic aromatic hydrocarbon (PAH). 7,12-Dimethylbenz[a]anthracene is used to induce tumor formation in various rodent models.
- GC42623 8-Bromoguanosine 8-Bromoguanosine is a brominated derivative of guanosine.
- GC42644 9-Deazaguanine 9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; Kd = 160 nM).
- GC42668 ABC34 ABC34 is an inactive control probe for JJH260, the inhibitor of androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs).
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GC42685
Ac-ANW-AMC
Ac-ANW-AMC is a fluorogenic substrate for the β5i/LMP7 subunit of the 20S immunoproteasome.
- GC18443 Acetyl-6-formylpterin Acetyl-6-formylpterin is an inhibitor of mucosal-associated invariant T (MAIT) cell activation.
- GC45681 AKP-11 An S1P1 receptor agonist
- GC45790 Artesunate-d4 An internal standard for the quantification of artesunate
- GC46895 Aurintricarboxylic Acid (ammonium salt) A protein synthesis inhibitor with diverse biological activities
- GC42877 AUY954 AUY954 is an orally bioavailable and selective agonist of the sphingosine-1-phosphate receptor 1 (S1P1; EC50 = 1.2 nM for stimulating GTPγS binding to S1P1 in CHO cells).
- GC42891 azido-FTY720 FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analog of sphingosine.
- GC49044 Benastatin C A bacterial metabolite with diverse biological activities
- GC52326 Biotin-PEG4-LL-37 (human) (trifluoroacetate salt) A biotinylated and pegylated form of LL-37
- GC18716 Bisindolylmaleimide XI (hydrochloride) Bisindolylmaleimide XI (BIM XI) is a selective, cell-permeable protein kinase C (PKC) inhibitor that displays 10-fold greater selectivity for PKCα (IC50 = 9 nM) and 4-fold greater selectivity for PKCβI (IC50 = 28 nM) over Ca2+-independent PKCε (IC50 = 108 nM).
- GA20972 Boc-D-Leu-OSu An amino acid-containing building block
- GC52101 Brazilein Brazilein is an important immunosuppressive component isolated from Caesalpinia sappan L.
- GC43007 C12 Galactosylceramide (d18:1/12:0) C12 Galactosylceramide is a bioactive sphingolipid.
- GC43032 C16 Globotriaosylceramide (d18:1/16:0) C16 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from C16 lactosylceramide.
- GC43049 C18 Globotriaosylceramide (d18:1/18:0) C18 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from lactosylceramide.
- GC40709 C2 L-threo Ceramide (d18:1/2:0) C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.
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GC43084
C4 Ceramide (d18:1/4:0)
C4 Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.
- GC40688 C6 D-threo Ceramide (d18:1/6:0) C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM).
- GC40690 C6 L-threo Ceramide (d18:1/6:0) C6 L-threo Ceramide (d18:1/6:0) is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.
- GC47040 Carebastine-d5 An internal standard for the quantification of carebastine
- GC43181 CAY10597 The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and CRTH2/DP2.
- GC40757 CAY10734 An S1P1 receptor agonist
- GC48427 CAY10774 A PD-1/PD-L1 interaction inhibitor
- GC49664 CB-1158 An arginase inhibitor
- GC49584 CD74 Monoclonal Antibody (Clone PIN1) For immunochemical analysis of CD74
- GC18392 Cellocidin Cellocidin is an antibiotic originally isolated from S.
- GC43239 Chk2 Inhibitor Chk2 Inhibitor (compound 1) is a potent and selective inhibitor of checkpoint kinase 2 (Chk2), with IC50s of 13.5 nM and 220.4 nM for Chk2 and Chk1, respectively. Chk2 Inhibitor can elicit a strong ataxia telangiectasia mutated (ATM)-dependent Chk2-mediated radioprotection effect.
- GC52153 CIN-16645 CIN-16645 is a cationic lipid useful in the delivery of biologically active agents to cells and tissues (extracted from patent WO2015095340 A1).
- GC47109 Clotrimazole-d5 An internal standard for the quantification of clotrimazole
- GC43288 Cochlioquinone A Cochlioquinone A, a bioactive compound isolated from D.
- GC43307 Concanamycin B Concanamycin B is a macrolide antibiotic that selectively inhibits vacuolar type H+-ATPases, also known as V-ATPases (IC50 = 5 nM).
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GC18572
Concanavalin A
Concanamycin A belongs to the concanamycins, a family of macrolide antibiotics isolated from Streptomyces diastatochromogenes that are highly active and selective inhibitors of the vacuolar proton-ATPase (v-[H+]ATPase).
- GC49021 CXCR3 Antagonist 6c A CXCR3 antagonist
- GC43340 Cyclic di-IMP (sodium salt) Cyclic di-IMP (sodium salt) (c-di-IMP) is a synthetic second messenger structurally related to the bacterial second messengers cyclic di-GMP and cyclic di-AMP.
- GC43350 Cyclosporin B Cyclosporin B is a minor cyclopeptide metabolite produced by T.
- GC49526 Cytidine-d2 An internal standard for the quantification of cytidine
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GC49153
Didemnin B
Didemnin B is a cyclic depsipeptide produced by marine tunicates that specifically binds the GTP-bound conformation of EEF1A.
- GC40629 Dimethoxycurcumin Naturally occurring phytochemicals such as turmeric (curcumin) have been found to inhibit the growth of tumor cells.
- GC43467 Dimethyldioctadecylammonium (bromide) Dimethyldioctadecylammonium (DDA) is a cationic amphipathic lipid.
- GC48352 Diprovocim-1 An agonist of TLR1/TLR2
- GC47257 Dodecanoyl D-Sucrose A nonionic surfactant
- GC40082 Drimentine B Drimentine B is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria.
- GC47278 Ebastine-d5 An internal standard for the quantification of ebastine
- GC52303 Ethyl Mycophenolate A potential impurity found in commercial preparations of mycophenolate mofetil
- GC43659 Feglymycin Feglymycin is a 13-amino acid peptide originally isolated from Streptomyces that has antibacterial and antiviral activities.
- GC18325 Ferrichrome (iron-free) Ferrichrome is a hydroxamate siderophore produced by various fungi, including U.
- GC46148 Filgotinib-d4 An internal standard for the quantification of filgotinib
- GC47351 Fingolimod-d4 An internal standard for the quantification of fingolimod
- GC47352 FK-506-13C-d2 An internal standard for the quantification of FK-506
- GC52014 Forphenicinol An immunomodulator and a derivative of forphenicine
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GC40887
FTY720 (R)-Phosphate
FTY720 is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.
- GC47387 G6PDi-1 An inhibitor of G6PDH
- GC18469 Galactosylcerebrosides (bovine) Galactosylcerebrosides are glycosphingolipids that contain a galactose attached to a ceramide acylated with hydroxy and non-hydroxy fatty acids.
- GC43721 Galactosylcerebrosides (hydroxy) Galactosylcerebrosides are glycosphingolipids that contain a galactose attached to a ceramide acylated with a hydroxy or non-hydroxy fatty acid.
- GC43722 Galactosylcerebrosides (non-hydroxy) Galactosylcerebrosides are glycosphingolipids that contain a galactose attached to a ceramide acylated with a hydroxy or non-hydroxy fatty acid.
- GC43730 Ganglioside GM1 Asialo Mixture Ganglioside GM1 asialo is a component of cellular lipid rafts and can be formed by the cleavage of the sialic acid residue from ganglioside GM1 by neuraminidase.
- GC47392 Ganglioside GM1 Mixture (ovine) (ammonium salt) A mixture of ganglioside GM1
- GC47398 Genistein-d4 An internal standard for the quantification of genistein
- GC47403 Gliovirin A fungal metabolite
- GC49798 Glyphosine A plant growth regulator
- GC43804 Halofuginone (hydrochloride) Halofuginone is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D.
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GC43807
HDMAPP (ammonium salt)
HDMAPP is a metabolite of the microbial dioxyxylulose-phosphate pathway, which is analogous to the isopentenyl pyrophosphate pathway in mammals.
- GC47434 Homodestcardin A fungal metabolite with immunosuppressant activity
- GC43879 Hydroxy Ebastine Hydroxy Ebastine is an ebastine metabolite.
- GC49282 Hydroxy Lenalidomide A metabolite of lenalidomide
- GC48548 iBET-BD2 A BD2 bromodomain inhibitor
- GC47456 Indole-3-pyruvic Acid Indole-3-pyruvic Acid, a keto analogue of tryptophan, is an orally active AHR agonist.
- GC40901 Isogarcinol Isogarcinol is a natural polyisoprenylated benzophenone first isolated from plant species in the genus Garcinia.
- GC52321 ISP-I-28 An immunosuppressant
- GC43928 JJH260 JJH260 is an N-hydroxy hydantoin carbamate that inhibits androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs).
- GC47533 L-778,123 A dual inhibitor of FTase and GGTase I
- GC47552 Leflunomide-d4 An internal standard for the quantification of leflunomide
- GC47553 Lenalidomide-d5 An internal standard for the quantification of lenalidomide