Autoimmunity
Products for Autoimmunity
- Cat.No. Product Name Information
- GC52253 α-Enolase (1-19)-biotin Peptide A biotinylated α-enolase peptide
- GC48292 α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) α-MSH (α-Melanocyte-Stimulating Hormone) TFA, an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities.
- GC40467 (±)11-HETE (±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid.
- GC45263 (+)-D-threo-PDMP (hydrochloride) (+)-D-threo-PDMP is a ceramide analog and is one of the four possible stereoisomers of PDMP.
- GC52185 (R,S)-Anatabine-d4
- GC49759 13C17-Mycophenolic Acid An internal standard for the quantification of mycophenolic acid
- GC49912 13C20,15N10-Cyclic di-GMP (sodium salt) An internal standard for the quantification of cyclic di-GMP
- GC41950 16α-hydroxy Estrone The naturally-occurring estrogens are estrone, estradiol, and estriol.
- GC42080 2'2'-cGAMP (sodium salt) 2'2'-cGAMP is a synthetic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds.
- GC40960 20α-dihydro Prednisolone 20α-dihydro Prednisolone is a metabolite of prednisolone.
- GC18527 4'-hydroxy Flurbiprofen A major active metabolite of flurbiprofen
- GC49127 4-oxo Cyclophosphamide An inactive metabolite of cyclophosphamide
- GC18582 5'-hydroxy Meloxicam A metabolite of meloxicam
- GC48381 5'-pApA (sodium salt) A linearized form of cyclic di-AMP
- GC48375 5'-pGpG (sodium salt) A linearized form of cyclic di-GMP
- GC52413 5-Aminosalicylic Acid-d7 An internal standard for the quantification of 5-aminosalicylic acid
- GC49629 6β-hydroxy Prednisolone A metabolite of prednisolone
- GC45772 6(5H)-Phenanthridinone An inhibitor of PARP1 and 2
- GC49235 6-Methylmercaptopurine A metabolite of 6-mercaptopurine
- GC49488 6-Methylmercaptopurine-d3 An internal standard for the quantification of 6-MMP
- GC49051 7-hydroxy Methotrexate A metabolite of methotrexate
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GC42608
7-hydroxy Methotrexate (sodium salt)
7-hydroxy Methotrexate (7-hydroxy MTX) is a phase I metabolite of MTX, which is converted by hepatic aldehyde oxidases.
- GC42644 9-Deazaguanine 9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; Kd = 160 nM).
- GC49238 93-O17S A cationic lipidoid
- GC42691 Aceclofenac ethyl ester A potential impurity found in commercial preparations of aceclofenac
- GC42692 Aceclofenac methyl ester A potential impurity in commercial preparations of aceclofenac
- GC40645 Actarit Actarit is an orally active immunomodulator that reduces symptoms in animal models and clinical trials of rheumatoid arthritis.
- GC45681 AKP-11 An S1P1 receptor agonist
- GC46867 Apremilast-d5 An internal standard for the quantification of apremilast
- GC45790 Artesunate-d4 An internal standard for the quantification of artesunate
- GC46895 Aurintricarboxylic Acid (ammonium salt) A protein synthesis inhibitor with diverse biological activities
- GC49646 Aurothioglucose (hydrate) A TrxR inhibitor
- GC42877 AUY954 AUY954 is an orally bioavailable and selective agonist of the sphingosine-1-phosphate receptor 1 (S1P1; EC50 = 1.2 nM for stimulating GTPγS binding to S1P1 in CHO cells).
- GC42880 Avenanthramide-C methyl ester Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM).
- GC49836 Benoxaprofen Benoxaprofen (LRCL 3794) is a potent and long-acting anti-inflammatory and antipyretic compound.
- GC52326 Biotin-PEG4-LL-37 (human) (trifluoroacetate salt) A biotinylated and pegylated form of LL-37
- GC42953 BMS 345541 (trifluoroacetate salt) BMS 345541 is a cell permeable inhibitor of the IκB kinases IKKα and IKKβ (IC50s = 4 and 0.3 μM).
- GC46946 BPC 157 (acetate) A pentadecapeptide with diverse biological activities
- GC46983 C-170 C-170 (C-170) is a potent and covalent STING inhibitor.
- GC46984 C-171 C-171 is an inhibitor of stimulator of interferon genes (STING).
- GC43007 C12 Galactosylceramide (d18:1/12:0) C12 Galactosylceramide is a bioactive sphingolipid.
- GC43076 C24 Phytosphingosine (t18:0/24:0) C24 Phytosphingosine (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis.
- GC43077 C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) C24:1 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids.
- GC47020 Calcium D-Glucarate (hydrate) The calcium salt form of D-glucaric acid
- GC49147 Carboxyphosphamide An inactive metabolite of cyclophosphamide
- GC43176 CAY10575 CAY10575 (Compound 8) is an IKK2 inhibitor with an IC50 of 0.075 μM.
- GC47054 CAY10748 A STING agonist
- GC45885 Chloroquine-d5 (phosphate) An internal standard for the quantification of chloroquine
- GC52351 Citrullinated α-Enolase (R8 + R14) (1-19)-biotin Peptide A biotinylated and citrullinated α-enolase peptide
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GC52363
Citrullinated Histone H3 (R2 + R8 + R17) (2-22)-biotin Peptide
A biotinylated and citrullinated histone H3 peptide
- GC52367 Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide A biotinylated and citrullinated mutant vimentin peptide
- GC52370 Citrullinated Vimentin (R144) (139-159)-biotin Peptide A biotinylated and citrullinated vimentin peptide
- GC49680 Clobetasone Propionate A corticosteroid
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GC18572
Concanavalin A
Concanamycin A belongs to the concanamycins, a family of macrolide antibiotics isolated from Streptomyces diastatochromogenes that are highly active and selective inhibitors of the vacuolar proton-ATPase (v-[H+]ATPase).
- GC45413 Cridanimod (sodium salt)
- GC45614 Cryogenine An alkaloid with anti-inflammatory activity
- GC47128 CU-32 A cGAS inhibitor
- GC47129 CU-76 A cGAS inhibitor
- GC43339 Cyclic di-AMP (sodium salt) Cyclic di-AMP (c-di-AMP) is a second messenger produced by bacteria but not by mammals.
- GC19526 Cyclic di-GMP (sodium salt) Cyclic di-GMP (sodium salt) is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic di-GMP (sodium salt) has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic di-GMP (sodium salt) can be used in cancer research.
- GC43340 Cyclic di-IMP (sodium salt) Cyclic di-IMP (sodium salt) (c-di-IMP) is a synthetic second messenger structurally related to the bacterial second messengers cyclic di-GMP and cyclic di-AMP.
- GC48397 Cyclic di-UMP (sodium salt) A pyrimidine-containing CDN
- GC47148 Cyclophosphamide-d4 An internal standard for the quantification of cyclophosphamide
- GC47193 Desethyl Hydroxychloroquine-d4 An internal standard for the quantification of desethyl hydroxychloroquine
- GC43444 Diclofenac Acyl-β-D-Glucuronide Diclofenac acyl-β-D-glucuronide is an active metabolite of diclofenac and the predominant metabolite in rat.
- GC47212 Diclofenac amide A prodrug form of diclofenac
- GC43447 Diclofenac methyl ester Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac.
- GC47213 Diclofenac-d4 An internal standard for the quantification of diclofenac
- GC40867 Diflorasone Diacetate Diflorasone is a corticosteroid with anti-inflammatory activity.
- GC43494 DL-threo-PDMP (hydrochloride) DL-threo PDMP is a mixture of ceramide analogs that contains two of the four possible stereoisomers of PDMP : D-threo (1R,2R) and L-threo (1S,2S) PDMP.
- GC52334 ENPP1 Inhibitor 4e An ENPP1 inhibitor
- GC52303 Ethyl Mycophenolate A potential impurity found in commercial preparations of mycophenolate mofetil
- GC47323 Etofenamate-d4 An internal standard for the quantification of etofenamate
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GC40565
Feprazone
Feprazone is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor that is 10-fold selective for COX-2 over COX-1.
- GC46148 Filgotinib-d4 An internal standard for the quantification of filgotinib
- GC47366 Flurbiprofen-d3 An internal standard for the quantification of flurbiprofen
- GC49074 Forphenicine A bacterial metabolite and an inhibitor of alkaline phosphatase
- GC52487 Ganglioside GM4 (chicken egg) (ammonium salt) A sphingolipid
- GC43804 Halofuginone (hydrochloride) Halofuginone is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D.
- GC49496 Homocitrulline-d3 An internal standard for the quantification of homocitrulline
- GC47445 Hydroxychloroquine-d4 (sulfate) An internal standard for the quantification of hydroxychloroquine
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GC43894
IKK2 Inhibitor VI
Inhibitor of NF-κB kinase 2 (IKK2, also known as IKKβ) acts as part of an IKK complex in the canonical NF-κB pathway, phosphorylating inhibitors of NF-κB (IκBs) to initiate signaling.
- GC40901 Isogarcinol Isogarcinol is a natural polyisoprenylated benzophenone first isolated from plant species in the genus Garcinia.
- GC52291 KAS 08 A STING activator
- GC52394 LC10 A lipidoid derivative of lithocholic acid
- GC47552 Leflunomide-d4 An internal standard for the quantification of leflunomide
- GC44078 LL-37 amide (trifluoroacetate salt) LL-37 is a cationic and α-helical antimicrobial peptide expressed in human bone marrow, testis, granulocytes, and gingival epithelium and is upregulated in psoriatic lesions.
- GC41452 Luteoloside Luteoloside is a flavonoid that has been found in many Chinese herbs with diverse biological activities.
- GC49916 Lys-(Des-Arg9, Leu8)-Bradykinin (trifluoroacetate salt) A bradykinin B1 receptor antagonist
- GC47649 Methotrexate (hydrate) A folic acid and aminopterin derivative
- GC47650 Methotrexate-d3 An internal standard for the quantification of methotrexate
- GC45998 Mitoxantrone-d8 An internal standard for the quantification of mitoxantrone
- GC52419 MOG (35-55) (mouse, rat) (trifluoroacetate salt) An MOG antigen peptide
- GC47712 Mycophenolate Mofetil-d4 An internal standard for the quantification of mycophenolate mofetil
- GC52385 Myelin Basic Protein (85-99) Peptide Antagonist (trifluoroacetate salt) An MBP (85-99) antagonist
- GC44257 Myelin Basic Protein (87-99) (human, bovine, rat) (trifluoroacetate salt) Myelin basic protein (MPB) (87-99) is an encephalitogenic peptide.
- GC40298 N-acetyl-5-Aminosalicylic Acid N-acetyl-5-Aminosalicylic acid is a metabolite of the anti-inflammatory agent 5-aminosalicylic acid and its prodrug form, sulfasalazine.
- GC44388 NF-κB Control NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells.
- GC48985 NF-κB Inhibitor (trifluoroacetate salt) A cell-permeable peptide that blocks nuclear import of NF-κB
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GC18895
NIBR0213
NIBR0213 is an orally bioavailable, potent, and selective antagonist of sphingosine-1-phosphate receptor-1 (S1P1) with IC50 values of 2.5 and 2.0 nM for the hS1P1 in a Ca2+ mobilization assay and GTPγS assay, respectively.