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Home >> Signaling Pathways >> Immunology/Inflammation >> Specialized Pro-Resolving Mediators

Specialized Pro-Resolving Mediators

Products for  Specialized Pro-Resolving Mediators

  1. Cat.No. Product Name Information
  2. GC40971 10(S),17(S)-DiHDHA Protectin D1 (also known as neuroprotectin D1 when produced in neuronal tissues) is a DHA-derived dihydroxy fatty acid that exhibits potent protective and anti-inflammatory activities. 10(S),17(S)-DiHDHA Chemical Structure
  3. GC41206 14(S)-HDHA Docosahexaenoic acid is a nutritionally-derived ω-3 fatty acid that is abundant in the brain and the retina and is thought to be important in early development and for therapeutic approaches to inflammatory disorders and cancer. 14(S)-HDHA Chemical Structure
  4. GC41415 15(R)-Lipoxin A4

    Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function.

     15(R)-Lipoxin A4 Chemical Structure
  5. GC41207 17(R)-HDHA Resolvins are a group of polyhydroxylated metabolites of docosahexaenoic acid (DHA) found in the inflammatory exudates of aspirin-treated experimental animals. 17(R)-HDHA Chemical Structure
  6. GC49178 17(R)-Protectin D1 An aspirin-triggered epimer of protectin D1 17(R)-Protectin D1 Chemical Structure
  7. GC41951 17(R)-Resolvin D1

    Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.

     17(R)-Resolvin D1 Chemical Structure
  8. GC41227 17(R)-Resolvin D1 methyl ester 17(R)-Resolvin D1 (17(R)-RvD1) is an aspirin-triggered epimer of RvD1 that reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with equipotency to RvD1 (EC50 = ~30 nM). 17(R)-Resolvin D1 methyl ester Chemical Structure
  9. GC45307 17(R)-Resolvin D3   17(R)-Resolvin D3 Chemical Structure
  10. GC41952 17(R)-Resolvin D4 17(R)-Resolvin D4 (17(R)-RvD4) is an aspirin-triggered epimer of RvD4 . 17(R)-Resolvin D4 Chemical Structure
  11. GC41208 17(S)-HDHA 17(S)-HDHA is a primary mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, and mouse brain. 17(S)-HDHA Chemical Structure
  12. GC40975 17(S)-HpDHA 17(S)-HpDHA is a mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, human glial cells, and mouse brain. 17(S)-HpDHA Chemical Structure
  13. GC41424 6(S)-Lipoxin A4 The lipoxins are trihydroxy fatty acids containing a 7,9,11,13-conjugated tetraene. 6(S)-Lipoxin A4 Chemical Structure
  14. GC46732 7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid A metabolite of DPA with antiinflammatory properties 7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid Chemical Structure
  15. GC40978 7-epi Maresin 1 7-epi Maresin 1 is the inactive 7(S) epimer of Maresin 1, which contains a 7(R) hydroxyl group. 7-epi Maresin 1 Chemical Structure
  16. GC49590 Docosahexaenoic Acid 1,2,3,4-13C An internal standard for the quantification of DHA Docosahexaenoic Acid 1,2,3,4-13C Chemical Structure
  17. GC18552 Lipoxin A4

    A trihydroxy fatty acid containing a conjugated tetraene

     Lipoxin A4 Chemical Structure
  18. GC18680 Lipoxin A4 methyl ester

    Lipoxin A4 methyl ester (LXA4 methyl ester) is a more lipid soluble, prodrug formulation of the transcellular metabolite LXA4.

     Lipoxin A4 methyl ester Chemical Structure
  19. GC47569 Lipoxin A4-d5 A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Lipoxin A4-d5 Chemical Structure
  20. GC40609 Lipoxin A5 Lipoxin A5 (LXA5) is produced by enzymatic transformation of EPA by leukocytes. Lipoxin A5 Chemical Structure
  21. GC18681 Lipoxin B4 Lipoxin B4 (LXB4) is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15(S)-HpETE by human leukocytes. Lipoxin B4 Chemical Structure
  22. GC41169 Lipoxin B4 methyl ester Lipoxin B4 (LXB4) methyl ester is a lipid soluble prodrug form of the transcellular metabolite LXB4. Lipoxin B4 methyl ester Chemical Structure
  23. GC40980 Maresin 2

    Docosahexaenoic acid is an ω-3 fatty acid that is abundant in the brain and the retina and is known to be important in early development.

     Maresin 2 Chemical Structure
  24. GC44138 MCTR1 Maresin conjugates in tissue regeneration 1 (MCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation. MCTR1 Chemical Structure
  25. GC44139 MCTR2 Maresin conjugates in tissue regeneration 2 (MCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation. MCTR2 Chemical Structure
  26. GC44140 MCTR3 Maresin conjugates in tissue regeneration 3 (MCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages. MCTR3 Chemical Structure
  27. GC44579 PCTR1 Protectin conjugates in tissue regeneration 1 (PCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid. PCTR1 Chemical Structure
  28. GC44580 PCTR2 Protein conjugates in tissue regeneration 2 (PCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid. PCTR2 Chemical Structure
  29. GC44581 PCTR3 Protein conjugates in tissue regeneration 3 (PCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid. PCTR3 Chemical Structure
  30. GC40981 Protectin D1 Protectin D1 is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid. Protectin D1 Chemical Structure
  31. GC49873 Protectin D1 methyl ester An esterified form of protectin D1 Protectin D1 methyl ester Chemical Structure
  32. GC48993 Protectin D1-d5 An internal standard for the quantification of protectin D1 Protectin D1-d5 Chemical Structure
  33. GC48035 RCTR1 A specialized pro-resolving mediator RCTR1 Chemical Structure
  34. GC41230 Resolvin D1 methyl ester Resolvin D1 is produced physiologically from the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase. Resolvin D1 methyl ester Chemical Structure
  35. GC48041 Resolvin D1-d5 An internal standard for the quantification of RvD1 Resolvin D1-d5 Chemical Structure
  36. GC41231 Resolvin D2 methyl ester Resolvin D2 (RvD2) is a lipid mediator biosynthesized by the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase. Resolvin D2 methyl ester Chemical Structure
  37. GC49279 Resolvin D2 n-3 DPA A specialized pro-resolving mediator Resolvin D2 n-3 DPA Chemical Structure
  38. GC48042 Resolvin D2-d5 An internal standard for the quantification of RvD2 Resolvin D2-d5 Chemical Structure
  39. GC41232 Resolvin D3 methyl ester Resolvin D3 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. Resolvin D3 methyl ester Chemical Structure
  40. GC44818 Resolvin D4

    Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid.

     Resolvin D4 Chemical Structure
  41. GC40982 Resolvin D5

    Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.

     Resolvin D5 Chemical Structure
  42. GC48972 Resolvin E2 A specialized pro-resolving mediator Resolvin E2 Chemical Structure
  43. GC48045 Resolvin E4 A specialized pro-resolving mediator Resolvin E4 Chemical Structure

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