Glucokinase
Glucokinase phosphorylates glucose to produce glucose-6-phosphate during the initial step of glycogenesis. Pancreatic glucokinase regulates insulin secretion. Hepatic glucokinase facilitates the uptake and conversion of glucose.
Products for Glucokinase
- Cat.No. Product Name Information
- GC18214 AM2394 A glucokinase activator
- GC19029 AMG-3969 AMG-3969 is a potent glucokinase-glucokinase regulatory protein interaction (GK-GKRP) disruptor with an IC50 of 4 nM.
- GC62846 AR453588 AR453588 is a potent and orally bioavailable anti-diabetic glucokinase activator, with an EC50 of 42 nM.
- GC68003 Cadisegliatin
- GC38784 GKA50 GKA50 is a potent glucokinase activator (EC50=33 nM at 5 mM glucose).
- GC61749 GKA50 quarterhydrate GKA50 quarterhydrate is a potent glucokinase activator (EC50=33 nM at 5 mM glucose) and stimulates insulin release from mouse islets of Langerhans.
- GC67901 Glucokinase activator 3
- GC66015 IHVR-11029 IHVR-11029 is a small molecule inhibitor of ER α-glucosidases, with an EC50 of 0.09 μM.
- GC13124 LY2608204 LY2608204 (LY2608204) is a activator of glucokinase (GK) with EC50 of 42 nM.
- GC44210 MK-0941 MK-0941 is a glucokinase activator with EC50 values of 0.24 and 0.065 μM at low (2.5 mM) and high (10 mM) concentrations of glucose, respectively.
- GC33765 Palmitelaidic Acid (9-trans-Hexadecenoic acid) Palmitelaidic Acid (9-trans-Hexadecenoic acid) (9-trans-Hexadecenoic acid) is the trans isomer of palmitoleic acid.
- GC36881 PF-04937319 PF-04937319 is a glucokinase activator (GKA) with EC50 value of 154.4 ?μM, one of the most promising strategies for the treatment of type 2 diabetes mellitus.
- GC31514 PF-04991532 PF-04991532 is a potent, hepatoselective glucokinase activator with EC50s of 80 and 100 nM in human and rat, respectively.
- GC31618 PSN-GK1 PSN-GK1 is a potent glucokinase activator with an EC50 of 0.13 μM.
- GC37546 Ro 28-1675 Ro 28-1675 is a potent allosteric glucokinase (GK) activator with an EC50 of 54 nM.