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5-Lipoxygenase

5-lipoxygenase catalyzes oxidation of AA at the 5-position to yield 5-HpETE and is a current target for pharmaceutical intervention in a number of diseases such as asthma, atherosclerosis and several cancers.

Products for  5-Lipoxygenase

  1. Cat.No. Product Name Information
  2. GC13379 1-Naphthyl 3,5-dinitrobenzoate dual 5-lipoxygenase and microsomal prostaglandin E synthase-1 inhibitor 1-Naphthyl 3,5-dinitrobenzoate  Chemical Structure
  3. GC10821 11-keto-β-Boswellic Acid 11-Keto-beta-boswellic acid (11-Keto-β-boswellic acid) is a pentacyclic triterpenic acid of the oleogum resin from the bark of the Boswellia serrate tree, popularly known as Indian Frankincense. 11-Keto-beta-boswellic acid has the anti-inflammatory activity is primarily due to inhibit 5-lipoxygenase (5-LOX) and subsequent leukotriene and nuclear factor-kappa B (NF-κB) activation and tumor necrosis factor alpha generation production. 11-keto-β-Boswellic Acid  Chemical Structure
  4. GC14282 3-acetyl-11-keto-β-Boswellic Acid 3-acetyl-11-keto-β-Boswellic Acid (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator. 3-acetyl-11-keto-β-Boswellic Acid  Chemical Structure
  5. GC14601 BW 755C dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways BW 755C  Chemical Structure
  6. GC10331 Ebselen A peroxynitrite scavenger Ebselen  Chemical Structure
  7. GC12159 HZ52 5-lipoxygenase inhibitor HZ52  Chemical Structure
  8. GC14751 Malotilate Stimulates hepatocyte regeneration Malotilate  Chemical Structure
  9. GC16046 Piriprost (potassium salt) 5-lipoxygenase inhibitor Piriprost (potassium salt)  Chemical Structure
  10. GC10451 U-73122 Inhibitor of phospholipase C, phospholipase A2, and 5-LO U-73122  Chemical Structure
  11. GC16014 Zileuton

    5-lipoxygenase (5-LOX) inhibitor, orally active

    Zileuton  Chemical Structure
  12. GC14435 Zileuton sodium 5-lipoxygenase and leukotrienes inhibitor Zileuton sodium  Chemical Structure

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