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Home >> Signaling Pathways >> Others >> Aldose reductase

Aldose reductase

Aldose reductase catalyzes the NADPH-dependent reduction of glucose to sorbitol. It is involved in the progression of diabetic and glactosemic complications.

Products for  Aldose reductase

  1. Cat.No. Product Name Information
  2. GC25009 2-Chloro-1-(4-fluorobenzyl)benzimidazole 2-Chloro-1-(4-fluorobenzyl)benzimidazole is an aldose reductase (ALR2) inhibitor which is used for preparation of disubstituted benzimidazole derivative. 2-Chloro-1-(4-fluorobenzyl)benzimidazole Chemical Structure
  3. GC35179 6-Methoxytricin 6-Methoxytricin (Compound 6) is an flavonoid isolated from Artemisia iwayomogi. 6-Methoxytricin Chemical Structure
  4. GC31376 Aldose reductase-IN-1 Aldose reductase-IN-1 (Aldose reductase-IN-1) is a inhibitor of aldose reductase with IC50 of 28.9 pM. Aldose reductase-IN-1 Chemical Structure
  5. GC11756 Alrestatin aldose reductase inhibitor Alrestatin Chemical Structure
  6. GC35309 Alrestatin sodium Alrestatin sodium is an inhibitor of aldose reductase, an enzyme involved in the pathogenesis of complications of diabetes mellitus, including diabetic neuropathy. Alrestatin sodium Chemical Structure
  7. GC38584 AT-007 AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase inhibitor for treatment of Galactosemia with an IC50 value of 100 pM. AT-007 Chemical Structure
  8. GC10332 EBPC aldose reductase inhibitor EBPC Chemical Structure
  9. GC10001 Epalrestat aldose reductase inhibitor Epalrestat Chemical Structure
  10. GC31487 Fidarestat (SNK 860) Fidarestat (SNK 860) (SNK 860) is an inhibitor of aldose reductase, with IC50s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) (SNK 860) has the potential to treat diabetic disease. Fidarestat (SNK 860) Chemical Structure
  11. GC31412 Imirestat (AL 1576) Imirestat (AL 1576) (AL 1576) is an aldose reductase inhibitor, used for the treatment of diabetes. Imirestat (AL 1576) Chemical Structure
  12. GN10088 Isoliquiritigenin Isoliquiritigenin Chemical Structure
  13. GC38810 Lidorestat Lidorestat (IDD-676) is a potent, selective and orally active aldose reductase inhibitor with an IC50 of 5 nM. Lidorestat Chemical Structure
  14. GC37053 Quercetin 3-gentiobioside Quercetin 3-gentiobioside is isolated from A. Quercetin 3-gentiobioside Chemical Structure
  15. GC31359 Ranirestat (AS-3201) Ranirestat (AS-3201) (AS-3201) potent and orally active aldose reductase (AR) inhibitor with IC50s of 11 nM and 15 nM for rat lens AR and recombinant human AR, respectively, and a Ki of 0.38 nM for recombinant human AR. Ranirestat (AS-3201) Chemical Structure
  16. GC31474 Risarestat (CT 112) Risarestat (CT 112) (CT-112), an aldose reductase inhibitor, is developed for the treatment of diabetic complications. Risarestat (CT 112) Chemical Structure
  17. GC37666 Sorbinil Sorbinil, is an Aldose reductase inhibitor (ARI). Sorbinil Chemical Structure
  18. GC10958 Statil Statil (ICI 128436) is an orally active, selective and noncompetitive aldose reductase (AKR1B1; ALR) inhibitor. Statil Chemical Structure
  19. GC37812 Tolrestat Tolrestat is a potent, orally active aldose reductase inhibitor with IC50 of 35 nM. Tolrestat Chemical Structure
  20. GC63990 Zenarestat Zenarestat is a potent and orally active aldose reductase inhibitor. Zenarestat Chemical Structure

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