Arginase
Arginase hydrolyzes L-argenine L-ornithine and urea in the urea cycle. Two arginase isoenzymes (arginase I and II ) play a role in regulation of nitric oxide (NO) synthesis and development of vascular diseases.
Products for Arginase
- Cat.No. Product Name Information
- GC61639 2-Aminoimidazole 2-Aminoimidazole is a potent antibiofilm agent that can be used as an adjuvant to antimicrobial.
- GC10096 Arginase inhibitor 1 Human arginases I and II inhibitor
- GC10280 BEC arginase inhibitor
- GC42911 BEC (hydrochloride) BEC is a potent slow-binding competitive inhibitor of recombinant rat liver arginase I with Ki values of 0.4 and 0.6 μM from kinetic analyses.
- GC33106 CB-1158 (INCB01158) CB-1158 (INCB01158) (CB-1158) is a potent and orally active inhibitor of arginase, with IC50s of 86 nM and 296 nM for recombinant human arginase 1 and recombinant human arginase 2, respectively. Immuno-oncology agent.
- GC34368 CB-1158 Hydrochloride (INCB01158 Hydrochloride)
- GA10879 H-DL-Nva-OH
- GC50434 Nor NOHA monoacetate Arginase inhibitor
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GC10628
nor-NOHA (acetate)
nor-NOHA (acetate) (alpha-amino acid N(omega) -Hydroxy-Nor-L-arginine) is a potent and reversible selective arginase inhibitor,
- GC63120 Numidargistat dihydrochloride Numidargistat (CB-1158) dihydrochloride is a potent and orally active inhibitor of arginase, with IC50s of 86 nM and 296 nM for recombinant human arginase 1 and recombinant human arginase 2, respectively. Immuno-oncology agent.
- GC36914 Piceatannol 3'-O-glucoside Piceatannol 3'-O-glucoside, an active component of Rhubarb, activates endothelial nitric oxide (NO) synthase through inhibition of arginase activity with IC50s of 11.22 ?M and 11.06 ?M against arginase I and arginase II, respectively.