FLAP
FLAP (5-lipoxygenase activating protein) is an integral protein within the nuclear membrane and is necessary for the activation of 5-lipoxygenase and therefore for the production of leukotrienes.
Products for FLAP
- Cat.No. Product Name Information
- GC31839 AM 103 AM 103 is a potent and selective FLAP inhibitor, with an IC50 value of 4.2 nM.
- GC62422 Atuliflapon Atuliflapon (AZD5718) is an orally active inhibitor of FLAP (5?Lipoxygenase activating protein), with an IC50 of 2 nM.
- GC12232 BAY-X 1005 BAY-X 1005 (BAY X 1005; DG-031) is an orally active and selective 5-lipoxygenase activating protein (FLAP) inhibitor.
- GC31689 Fiboflapon (GSK2190915) Fiboflapon (GSK2190915) (GSK2190915; AM-803) is a potent and orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood.
- GC15506 GSK2190915 sodium salt GSK2190915 sodium salt (GSK2190915; AM-803) is a potent and orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood.
- GC12277 MK 886 FLAP and PPARα inhibitor, inhibits leukotriene biosynthesis
- GC11457 MK-0591 An inhibitor of FLAP
- GC37059 Quiflapon sodium Quiflapon sodium (MK-591 sodium) is a selective and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor.