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FLAP

FLAP (5-lipoxygenase activating protein) is an integral protein within the nuclear membrane and is necessary for the activation of 5-lipoxygenase and therefore for the production of leukotrienes.

Products for  FLAP

  1. Cat.No. Product Name Information
  2. GC31839 AM 103 AM 103 is a potent and selective FLAP inhibitor, with an IC50 value of 4.2 nM. AM 103  Chemical Structure
  3. GC62422 Atuliflapon Atuliflapon (AZD5718) is an orally active inhibitor of FLAP (5?Lipoxygenase activating protein), with an IC50 of 2 nM. Atuliflapon  Chemical Structure
  4. GC12232 BAY-X 1005 BAY-X 1005 (BAY X 1005; DG-031) is an orally active and selective 5-lipoxygenase activating protein (FLAP) inhibitor. BAY-X 1005  Chemical Structure
  5. GC31689 Fiboflapon (GSK2190915) Fiboflapon (GSK2190915) (GSK2190915; AM-803) is a potent and orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood. Fiboflapon (GSK2190915)  Chemical Structure
  6. GC15506 GSK2190915 sodium salt GSK2190915 sodium salt (GSK2190915; AM-803) is a potent and orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood. GSK2190915 sodium salt  Chemical Structure
  7. GC12277 MK 886 FLAP and PPARα inhibitor, inhibits leukotriene biosynthesis MK 886  Chemical Structure
  8. GC11457 MK-0591 An inhibitor of FLAP MK-0591  Chemical Structure
  9. GC37059 Quiflapon sodium Quiflapon sodium (MK-591 sodium) is a selective and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor. Quiflapon sodium  Chemical Structure

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