Gutathione S-transferase
GSTs (Glutathione s-transferases)is a detoxification enzyme that catalyze the binding of electrophilic substrates to glutathione. They involved in removal of ROS, inhibition of Jun kinase and can conjugate non-catalytically to various ligands.
Products for Gutathione S-transferase
- Cat.No. Product Name Information
- GC64919 AZD9898 AZD9898 is an orally active leukotriene-C4 synthetase (LTC4S, glutathione S-transferase II) inhibitor, with an IC50 of 0.28 nM.
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GC35727
Coniferyl ferulate
A monolignal conjugate with diverse biological activities
- GC35759 Curzerene Curzerene is a sesquiterpene is isolated from the rhizome of Curculigo orchioides Gaertn with anti-cancer activity. Curzerene inhibits glutathione S-transferase A1 (GSTA1) mRNA and protein expression. Curzerene induces cell apoptosis.
- GC10519 Ethacrynic acid - d5 Used as an internal standard for GC- or LC-mass spectrometry
- GC13409 Ezatiostat hydrochloride GST inhibitor
- GC33342 GSTO-IN-2 GSTO-IN-2 is a glutathione S-transferase inhibitor with IC50s of 3.6, 16.3, and 1.4 μM for GSTA2, GSTM1, and GSTP1-1.
- GC32971 GSTO1-IN-1 GSTO1-IN-1 is a potent glutathione S-transferase omega 1 (GSTO1) inhibitor with an IC50 of 31 nM.
- GC17287 Iberin induces the expression of phase II detoxification enzymes, including quinone reductase and glutathione S-transferase
- GC63518 LAS17 LAS17 is a potent and selective tyrosine-directed irreversible inhibitor for glutathione?S-Transferase Pi (GSTP1) . LAS17 inhibits GSTP1 activity with an IC50 of 0.5 ?M.
- GC44882 Seneciphylline Seneciphylline is an alkaloid that has been found F.
- GC65438 TK05 TK05 is a potent and selective inhibitor of leukotriene C4 synthase (LTC4S) with an IC50 of 95 nM.
- GC30647 TLK117 (TER117) TLK117 (TER117), the active metabolite of TLK199, selective inhibits Glutathione S-transferase P1-1 (GSTP1-1) with a Ki of 0.4 μM for GSTP.