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Proteases

Proteases, also known as peptidases or proteolytic enzymes, consists of a large number of enzymes catalyzing the hydrolysis of peptide bonds and subsequently resulting in the degradation of protein substrates into amino acids. Proteases are involved in a wide range of human diseases, including cancer, neurodegenerative disorders, inflammatory diseases and cardiovascular diseases. Thus numerous proteases inhibitors (small molecules and proteins) have been identified to block activity of proteases. Proteases inhibitors can be classified into different types based on the class of proteases they inhibit through two general mechanisms, irreversible “trapping” reactions and reversible tight-binding reactions. Proteases inhibitors have been used as diagnostic or therapeutic agents for the treatment of proteases-related diseases.

Products for  Proteases

  1. Cat.No. Product Name Information
  2. GC38287 α-Pyridone
  3. GC38000 β-Boswellic acid
  4. GC38010 γ-Aminobutyric acid
  5. GC38011 γ-Secretase modulator 4
  6. GC15975 α-Estradiol Endogenous estrogen receptor ligand
  7. GC34961 (±)-BI-D
  8. GC41670 (±)-Epinephrine (hydrochloride) (±)-Epinephrine is a natural neurotransmitter that is released from the adrenal medulla and activates adrenoceptors (Kis = 15, 735, and 3,970 nM for α1A-, β2-, and β1-adrenergic receptors, respectively).
  9. GC38369 (±)-Leucine
  10. GC13890 (±)-Palmitoylcarnitine chloride intermediate in mitochondrial fatty acid oxidation
  11. GC30586 (±) Anabasine
  12. GC10675 (+,-)-Octopamine HCl adrenoceptor agonist
  13. GC17470 (-)-Cotinine α3/α6β2 nAChR activator
  14. GC17242 (-)-epigallocatechin green tea epicatechin
  15. GC14049 (-)-Epigallocatechin gallate (EGCG) Antioxidant, antiangiogenic and antitumor agent
  16. GC31620 (-)-Fucose (6-Desoxygalactose)
  17. GC38299 (2-Aminoethyl)phosphonic acid
  18. GC38265 (2R,3R)-2,3-Dihydroxysuccinic acid
  19. GC38296 (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride
  20. GC33797 (3-Carboxypropyl)trimethylammonium chloride (γ-Butyrobetaine hydrochloride)
  21. GC38144 (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one

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