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Home >> Signaling Pathways >> TGF-β / Smad Signaling >> SMAD

SMAD

SMAD are intracellular proteins that transduce extracellular signals from transforming growth factor beta ligands to the nucleus where they activate downstream gene transcription.

Products for  SMAD

  1. Cat.No. Product Name Information
  2. GC41863 10,11-dehydro Curvularin A natural mycotoxin 10,11-dehydro Curvularin Chemical Structure
  3. GN10534 Asiaticoside Asiaticoside Chemical Structure
  4. GC32250 Chebulinic acid An ellagitannin with diverse biological activities Chebulinic acid Chemical Structure
  5. GC34060 Disitertide (P144) Disitertide (P144) (P144) is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide (P144) (P144) is also a PI3K inhibitor and an apoptosis inducer. Disitertide (P144) Chemical Structure
  6. GC32914 EMT inhibitor-1 EMT inhibitor-1 is an inhibitor of of Hippo, TGF-β, and Wnt signaling pathways with antitumor activities. EMT inhibitor-1 Chemical Structure
  7. GC31650 Halofuginone (RU-19110) Halofuginone (RU-19110) (RU-19110), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone (RU-19110) Chemical Structure
  8. GC31950 Halofuginone hydrobromide (RU-19110 (hydrobromide)) Halofuginone (RU-19110) hydrobromid, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone hydrobromide (RU-19110 (hydrobromide)) Chemical Structure
  9. GC17523 Hydrochlorothiazide diuretic drug of the thiazide class Hydrochlorothiazide Chemical Structure
  10. GC15057 Kartogenin Promote differentiation of multipotent MSCs into chondrocytes Kartogenin Chemical Structure
  11. GC16580 LDN-193189 ALK inhibitor,potent and selective LDN-193189 Chemical Structure
  12. GC14931 LDN193189 Hydrochloride An inhibitor of BMP receptors ALK1, ALK2, ALK3, and ALK6 LDN193189 Hydrochloride Chemical Structure
  13. GC11604 LY364947

    Inhibitor of TGF-β type I receptor kinase domain

     LY364947 Chemical Structure
  14. GN10378 Oxymatrine Oxymatrine Chemical Structure
  15. GC12790 Pirfenidone TGF-β production inhibitor Pirfenidone Chemical Structure
  16. GC16793 RepSox A selective inhibitor of ALK5 RepSox Chemical Structure
  17. GC17191 SIS3 HCl SIS3HCl is a potent and selective inhibitor of Smad3 with an IC50 of 3 μM for Smad3 phosphorylation. SIS3 HCl Chemical Structure
  18. GC44903 SMAD3 Inhibitor, SIS3 SMAD3 Inhibitor, SIS3 is a potent and selective inhibitor of Smad3 phosphorylation. SMAD3 Inhibitor, SIS3 Chemical Structure
  19. GC19338 SRI-011381 hydrochloride An oral bioavailabile TGF-beta signaling agonist SRI-011381 hydrochloride Chemical Structure

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