Pyk2

Pyk2 is a nonreceptor cytoplasmic protein tyrosine kinase. It is involved in Ca(2+)-induced regulation of ion channel and MAP kinase activation. It plays a role in various cellular events such as cell motility, cell polarization, adhesion, reorganization of actin cytoskeleton etc.

Products for Pyk2

Cat.No. Product Name Information
GC14767 PF-00562271 PF-562271 (VS-6062) besylate is a potent ATP-competitive, reversible inhibitor of FAK and Pyk2 kinase, with an IC50 of 1.5 nM and 13 nM, respectively.
GC14407 PF-431396 Pyk2 and FAK inhibitor
GC61852 PF-4618433 PF-4618433 is a potent and selective PYK2 inhibitor, with an IC50 of 637 nM.
GC15380 PF-562271 ATP-competitive FAK inhibitor, reversible
GC10810 PF-562271 HCl PF-562271 (VS-6062) hydrochloride is a potent, ATP-competitive and reversible FAK and Pyk2 kinase inhibitor with IC50s of 1.5 nM and 13 nM, respectively.
GC16821 TAE226(NVP-TAE226) TAE226(NVP-TAE226) (TAE226) is a potent and ATP-competitive dual FAK and IGF-1R inhibitor with IC50s of 5.5 nM and 140 nM, respectively.