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Filovirus

Filoviruses is amongst the most lethal of primate pathogens. Filoviruses cause lethal hemorrhagic fever in humans and nonhuman primates. The family Filoviridae includes two genera: Marburgvirus, comprising various strains of the Lake Victoria marburgvirus (MARV); and Ebolavirus (EBOVs), comprising four species including Sudan ebolavirus (SEBOV), Zaire ebolavirus (ZEBOV), Ivory Coast ebolavirus (CIEBOV), and Reston ebolavirus (REBOV); and a tentative species Bundibugyo ebolavirus (BEBOV).

The infections typically affect multiple organs in the body and are often accompanied by hemorrhage (bleeding). Once the virus has been transmitted from an animal host to a human, it can then spread through person-to-person contact.

Targets for  Filovirus

Products for  Filovirus

  1. Cat.No. Product Name Information
  2. GC67627 2'-Deoxy-5'-O-DMT-2'-fluorouridine 2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5'-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity. 2'-Deoxy-5'-O-DMT-2'-fluorouridine  Chemical Structure
  3. GC14314 Aloperine An alkaloid Aloperine  Chemical Structure
  4. GC43228 Cephaeline Cephaeline is an alkaloid originally isolated from C. Cephaeline  Chemical Structure
  5. GC32092 Galidesivir (BCX 4430) Galidesivir (BCX 4430) (BCX4430), an adenosine analog and a direct-acting antiviral agent, disrupts viral RNA-dependent RNA polymerase (RdRp) activity. Galidesivir (BCX 4430)  Chemical Structure
  6. GC32089 Galidesivir hydrochloride (BCX 4430 (hydrochloride)) Galidesivir (BCX4430) hydrochloride, an adenosine analog and a direct-acting antiviral agent, disrupts viral RNA-dependent RNA polymerase (RdRp) activity. Galidesivir hydrochloride (BCX 4430 (hydrochloride))  Chemical Structure

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