HBV
HBV (hepatitis B virus) is a double-strand DNA virus that belongs to the hepadaviridase famlity. It cause transient and acute liver infections which lead to cirrhosis and liver cancer. It is propagated through blood, sex and mother-fetus transmission.
Products for HBV
- Cat.No. Product Name Information
- GC65363 (1R)-Tenofovir amibufenamide (1R)-Tenofovir amibufenamide ((1R)-HS-10234) is the isomer of Tenofovir amibufenamide, is an orally active antiviral agent.
- GC67328 2'-Deoxy-L-adenosine 2'-Deoxy-L-adenosine is an orally active synthon for modified oligodeoxyribonucleotides. 2'-Deoxy-L-adenosine is a potent, specific and selective inhibitor of the replication of hepatitis B virus (HBV) as well as the closely related duck and woodchuck hepatitis viruses (WHV).
- GC33912 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) (Isochlorogenic acid C) is an antioxidant, can be isolated from Gynura divaricata and Laggera alata.
- GC39196 4-Hydroxyacetophenone 4-Hydroxyacetophenone (P-hydroxyacetophenone) is a key hepatoprotective and choleretic compound in Artemisia capillaris and A.
- GC19014 AB-423 AB-423 is an inhibitor of HBV capsid assembly, and potent inhibits HBV replication with EC50/EC90 of 0.08-0.27 uM/0.33-1.32 uM in cells.
- GC42731 Adefovir Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor.
- GC16841 Adefovir Dipivoxil Reverse transcriptase inhibitor
- GC61821 AT-130 AT-130, a phenylpropenamide derivative, is a potent hepatitis B virus (HBV) replication non-nucleoside inhibitor.
- GN10377 Aucubin
- GC60616 AZT triphosphate AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) is a active triphosphate metabolite of Zidovudine (AZT).
- GC60617 AZT triphosphate TEA AZT triphosphate TEA (3'-Azido-3'-deoxythymidine-5'-triphosphate TEA) is a active triphosphate metabolite of Zidovudine (AZT).
- GC35454 BA-53038B BA-53038B is a HBV core protein allosteric modulator (CpAM), binding to the HAP pocket and modulating HBV capsid assembly.
- GC32065 Bay 41-4109 (Bayer 41-4109) BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM.
- GC32197 Bay 41-4109 less active enantiomer (Bayer 41-4109 less active enantiomer) Bay 41-4109 less active enantiomer shows less activity than Bay 41-4109.
- GC32115 Bay 41-4109 racemate An antiviral agent
- GC68297 Bepirovirsen
- GC63421 Bersacapavir Bersacapavir is a novel Hepatitis B Virus capsid assembly modulator.
- GC38517 Besifovir Besifovir (LB80331), a parent drug converted by LB80380, further metabolizes to its active form, LB80317.
- GC18304 Bicyclol Bicyclol is a hepatoprotective agent.
- GC39348 Bifendate Bifendate (DDB) is a synthetic intermediate of Schisandrin C with anti-HBV efficacy in research of chronic hepatitis B.
-
GC11689
Cetylpyridinium Chloride
Cationic quaternary ammonium compound used as oropharyngeal antiseptic.
-
GC68859
Chamaechromone
Chamaechromone is a flavonoid component isolated from the roots of plants in the thyme family. It has anti-hepatitis B virus (HBV) activity, inhibits the surface secretion antigen (HBsAg) of hepatitis B virus, and also has insecticidal activity.
- GC12635 Clevudine antiviral drug
- GC17567 Doxorubicin (Adriamycin) HCl Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent.
- GC32093 Entecavir (BMS200475) Entecavir (BMS200475) (SQ 34676; BMS 200475) is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell.
- GC16092 Entecavir Hydrate Entecavir Hydrate (BMS200475 monohydrate; SQ34676 monohydrate) is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell.
- GC38785 GLP-26 GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM), and reduces cccDNA by >90% at 1 μM.
- GC12555 GS-9620 A TLR7 agonist
-
GP10047
HBcAg [Hepatitis B virus] (18-27)
Indicator of active viral replication
- GC63003 HBF-0259 HBF-0259 is a potent and selective inhibitor of hepatitis B virus (HBV) surface antigen (HBsAg) secretion, with an EC50 of 1.5 μM in HepG2.2.15 cells.
- GC62328 HBV-IN-4 HBV-IN-4, a phthalazinone derivative, is a potent and orally active HBV DNA replication inhibitor with an IC50 of 14 nM.
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GC10418
Helioxanthin
novel inhibitor of HBV, HCV and HSV-1 virus
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GC13722
Helioxanthin 8-1
inhibitor of HBV and HIV virus
- GC12615 Helioxanthin derivative 5-4-2 HBV/HSV-1/HSV-2 virus inhibitor
- GC36217 Hepatitis B Virus Core 128-140 Hepatitis B Virus Core 128-140 is a peptide of hepatitis B virus core protein.
- GC32104 Inarigivir (ORI-9020) Inarigivir (ORI-9020) (ORI-9020) is a dinucleotide antiviral drug that can significantly reduce liver HBV DNA in transgenic mice expressing hepatitis B virus.
- GC63021 Inarigivir ammonium Inarigivir (ORI-9020) ammonium is a dinucleotide antiviral drug that can significantly reduce liver HBV DNA in transgenic mice expressing hepatitis B virus.
- GC61455 IR415 IR415 is a potent anti-HBV agent and inhibits HBV replication by blocking the HBx activity.
- GN10264 Isochlorogenic acid A
- GC36342 Isoscopoletin A coumarin with diverse biological activities and an active metabolite of scoparone
- GC19208 JNJ-632 JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator (CAM).
- GC32287 Lagociclovir (MIV-210) Lagociclovir (MIV-210)(MIV-210) is a prodrug of 3'-fluoro-2',3'-dideoxyguanosine with high oral bioavailability in humans and potent activity against HBV.
- GC13522 Merimepodib Novel noncompetitive inhibitor of IMPDH(Inosine monophosphate dehydrogenase).
- GC32073 Morphothiadin (GLS4) Morphothiadin (GLS4) is a potent inhibitor on the replication of both wild-type and adefovir-resistant HBV with an IC50 of 12 nM.
- GC17997 Niranthin antiviral activities, blocking the replication of hepatitis B virus.
- GC32144 Osalmid (Oxaphenamide) Osalmid (Oxaphenamide) is a ribonucleotide reductase small subunit M2 (RRM2) targeting compound; suppresses ribonucleotide reductase activity with an IC50 of 8.23 μM.
- GC10997 Oxethazaine Topical anesthetic
- GC62658 PD-1/PD-L1-IN 7 PD-1/PD-L1-IN 7 (PD-1/PD-L1-IN 7) is a human PD-1/PD-L1 protein/protein interaction inhibitor with an IC50 of 0.213 nM.
- GN10361 Pseudolaric Acid B
- GC32193 RG7834 (RO 7020322) RG7834 (RO 7020322) (RO 7020322) is a highly selective and orally bioavailable HBV inhibitor, potently inhibits HBV antigens (both HBsAg and HBeAg) and HBV DNA, with IC50s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells.
- GC33932 RIG-1 modulator 1 RIG-1 modulator 1 is an anti-viral compound which can be useful for the treatment of viral infections including influenza virus, HBV, HCV and HIV extracted from patent WO 2015172099 A1.
- GC32071 Squalamine (MSI-1256) Squalamine (MSI-1256)(MSI-1256) is an aminosterol compound with potent broad spectrum antiviral activity.
-
GP10068
surface antigen (208-215) [Hepatitis B Virus]
Surface antigen used for signs of infection
- GC38982 Swertianolin Swertianolin, a xanthone isolated from Gentianella Acuta, inhibits acetylcholinesterase (AChE).
- GC37740 Taribavirin Taribavirin is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus.
- GC38559 Taribavirin hydrochloride Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus.
- GC11295 Telbivudine Reverse Transcriptase inhibitor
-
GC12125
Tenofovir
HIV reverse transcriptase inhibitor
- GC64918 Tenofovir amibufenamide Tenofovir amibufenamide (HS-10234), a Tenofovir prodrug, is an orally active antiviral agent.
- GC37760 Tenofovir Disoproxil Tenofovir Disoproxil (Bis(POC)-PMPA) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
- GC15067 Tenofovir Disoproxil Fumarate Antiretroviral agent( HIV-1 RT inhibitor)
- GC45031 Thiamine (hydrochloride) Thiamine is a water-soluble vitamin with antioxidant, neuroprotective, and anxiolytic properties.
- GC61339 Torcitabine Torcitabine (2'-Deoxy-L-cytidine) is an antiviral agent.
-
GC70054
trans-ccc_R08
trans-ccc_R08 (compound 1-B) is an effective inhibitor of cccDNA (covalently closed circular DNA). trans-ccc_R08 inhibits HBeAg levels with an IC50 value of 0.08 µM. trans-ccc_R08 has the potential to be used in research on hepatitis B virus (HBV) infection.
- GC63250 Vebicorvir Vebicorvir (ABI-H0731) is a first-generation hepatitis B virus (HBV) core protein inhibitor.
- GC67195 Vidarabine phosphate Vidarabine phosphate (Ara-AMP), an antiviral agent, inhibits chronic HBV infection. Vidarabine phosphate also against herpes simplex and varicella zoster viruses.