HIV
HIV (human immunodeficiency virus) is a lentivirus that infect immune system. It cause immune system failure and lead to AIDS (acquired immnudeficiency syndrome).
Products for HIV
- Cat.No. Product Name Information
- GC45604 β-Rubromycin β-Rubromycin is a potent and selective inhibitor of human immunodeficiency virus-1 (HIV-1) RNA-directed DNA polymeras (reverse transcriptase).
- GC34961 (±)-BI-D (±)-BI-D is a potent ALLINI(An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site.
- GC18516 (+)-Aeroplysinin-1 (+)-Aeroplysinin-1 is a metabolite originally isolated from the marine sponge V.
- GC18749 (+)-Rugulosin (+)-Rugulosin is a pigment and mycotoxin produced by certain fungi.
- GC14049 (-)-Epigallocatechin gallate (EGCG) (-)-Epigallocatechin Gallate sulfate (EGCG) is a major polyphenol in green tea that inhibits cell proliferation and induces apoptosis. In addition, it inhibits the activity of glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) ..
- GC46245 (-)-G-Lactone A bicyclic γ-lactone
- GC65363 (1R)-Tenofovir amibufenamide (1R)-Tenofovir amibufenamide ((1R)-HS-10234) is the isomer of Tenofovir amibufenamide, is an orally active antiviral agent.
- GC64260 (2S,5S)-Censavudine (2S,5S)-Censavudine ((2S,5S)-OBP-601) is the (2S,5S)-enantiomer of Censavudine.
- GC35009 (Z)-9-Propenyladenine (Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate.
- GC35035 1,3,5-Tricaffeoylquinic acid 1,3,5-Tricaffeoylquinic acid is a tricaffeoylquinic acid derivative isolated from H.
- GC46415 12-Bromododecanoic Acid A halogenated form of lauric acid
- GC18778 16,16-dimethyl Prostaglandin A1 16,16-dimethyl PGA1 is a metabolism resistant analog of PGA1.
- GC52501 2',3'-Dideoxyadenosine 5'-triphosphate (lithium salt) An inhibitor of reverse transcriptases and DNA polymerases
- GC46508 2',2'-Difluoro-2'-deoxyuridine An active metabolite of gemcitabine
- GC33994 2',3'-Dideoxyadenosine 2',3'-Dideoxyadenosine is an inhibitor of HIV replication.
- GC42171 2-hydroxy Stearic Acid methyl ester 2-hydroxy Stearic acid is a hydroxylated fatty acid methyl ester that broadens phase transition in dimyristoylphosphatidylcholine (DMPC) lipid membranes.
- GC61674 2-Hydroxyacetophenone 2-Hydroxyacetophenone is a principal root volatile of the Carissa edulis.
- GC61753 2-Hydroxycinnamic acid 2-Hydroxycinnamic acid is isolated from the methanol extract of Cinnamomum cassia.
- GC65085 3'-Azido-3'-deoxy-5-methylcytidine 3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 μM in MCF-7 cells.
- GC49122 3′-deoxy Thymidine An antiviral nucleoside analog
- GC49871 3’-Azido-2’,3’-dideoxyuridine An antiviral nucleoside analog
- GC42312 3'-Sialyllactose (sodium salt) 3'-Sialyllactose consists of the monosaccharide N-acetylneuraminic acid linked to the galactosyl subunit of lactose at the 3 position.
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GC14713
3-Deazaadenosine
3-Deazaadenosine (hydrochloride) is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.
- GC33842 3-Deazaadenosine hydrochloride An inhibitor of S-adenosylhomocysteine
- GC45337 3-Hydroxyterphenyllin 3-Hydroxyterphenyllin is a metabolite of Aspergillus candidus.3-Hydroxyterphenyllin suppresses proliferation and causes cytotoxicity against A2780/CP70 and OVCAR-3 cells. 3-Hydroxyterphenyllin induces S phase arrest and apoptosis. 3-Hydroxyterphenyllin has the potential for the research of ovarian cancer.
- GC48488 3-Oxobetulin Acetate A derivative of betulin
- GC35130 4'-Ethynyl-2'-deoxyadenosine 4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity.
- GC18853 4-isocyanato TEMPO 4-isocyanato TEMPO is a spin labeling reagent used to label the 2'-position in RNA.
- GC46075 5,6-dimethyl-2-Thiouracil A heterocyclic building block
- GC52091 5,7-Dichlorothiazolo[5,4-d]pyrimidine A building block
- GC35147 5-(N,N-Hexamethylene)-amiloride An amiloride derivative with diverse biological activities
- GC19536 6'-Sialyllactose Sodium Salt 6'-Sialyllactose (sodium), a predominant milk oligosaccharide, reduces the internalisation of Pseudomonas aeruginosa in human pneumocytes.
- GC46721 6-Chloro-2-fluoropurine A heterocyclic building block
- GC30119 9-Aminoacridine (Aminacrine) 9-Aminoacridine (Aminacrine) (Aminacrine) is a highly fluorescent dye used as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator.
- GC35208 9-Propenyladenine 9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate.
- GC13805 Abacavir
- GC42667 Abacavir Carboxylate Abacavir carboxylate is an inactive metabolite of the HIV-1 reverse transcriptase inhibitor abacavir.
- GC46767 Abacavir-d4 An internal standard for the quantification of abacavir
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GC19409
ABBV-744
ABBV-744 is a BDII-selective BET bromodomain inhibitor
- GC32145 ABX464 ABX464 (ABX464) is a potent anti-HIV agent.
- GA20545 Acetyl-Pepstatin Acetyl-pepstatin is reported to be an effective inhibitor of HIV-1 proteinase (Ki = 20 nM at pH 4.7) and of HIV-2 proteinase (Ki = 5 nM at pH 4.7). Ac-Val-Val-Sta-Ala-Sta also inhibits the P. falciparum aspartyl protease plasmepsin II, IC?? 0.6 nM.
- GC46805 Adefovir-d4 An internal standard for the quantification of adefovir
- GC41080 Albofungin Albofungin is a xanthone isolated from A.
- GC14314 Aloperine An alkaloid
- GC10473 AMD 3465 CXCR4 antagonist,potent and selective
- GC16706 AMD 3465 hexahydrobromide potent, selective CXCR4 antagonist
- GC12196 AMD-070 A CXCR4 antagonist
- GC60047 Amphotericin B methyl ester Amphotericin B methyl ester is the methyl ester derivative of the polyene antibiotic Amphotericin B (A634250).
- GC14152 Amprenavir (agenerase) A selective HIV protease inhibitor
- GC62842 Amylmetacresol Amylmetacresol possesses antiviral (such HIV) effect.
- GC52427 Apelin-12 (human, mouse, rat, bovine) (acetate) An endogenous agonist of the APJ receptor
- GC32336 Aplaviroc (AK 602) Aplaviroc (AK 602) (AK 602), a SDP derivative, is a CCR5 antagonist, with IC50s of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW.
- GC62610 Aplaviroc hydrochloride Aplaviroc (AK 602) hydrochloride, a SDP derivative, is a CCR5 antagonist, with IC50s of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW.
- GC15200 Aprepitant Substance P (SP) inhibitor
- GC49776 Apricitabine
- GC12945 Atazanavir An inhibitor of HIV-1 protease
- GC10240 Atazanavir sulfate (BMS-232632-05) An inhibitor of HIV-1 protease
- GC46887 Atazanavir-d6 An internal standard for the quantification of atazanavir
- GC46895 Aurintricarboxylic Acid (ammonium salt) A protein synthesis inhibitor with diverse biological activities
- GC49646 Aurothioglucose (hydrate) A TrxR inhibitor
- GC65963 AzddMeC AzddMeC (CS-92) is an antiviral nucleoside analogue and a potent potent, selective and orally active HIV-1 reverse transcriptase and HIV-1 replication inhibitor. In HIV-1-infected human PBM cells and HIV-1-infected human macrophages, the EC50 values of AzddMeC are 9 nM and 6 nM, respectively.
- GC60616 AZT triphosphate AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) is a active triphosphate metabolite of Zidovudine (AZT).
- GC60617 AZT triphosphate TEA AZT triphosphate TEA (3'-Azido-3'-deoxythymidine-5'-triphosphate TEA) is a active triphosphate metabolite of Zidovudine (AZT).
- GC39526 Azulene Azulene (Cyclopentacycloheptene) is as an isomer of naphthalene with high anti-HIV activity.
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GN10018
Baicalin
A flavonoid with diverse biological activities
- GC35487 Bellidifolin Bellidifolin is a xanthone isolated from the stems of Swertia punicea, with hepatoprotective, hypoglycemic, anti-oxidation, anti-inflammatory and antitumor activities.
- GC49038 Benanomicin A A microbial metabolite with antifungal, fungicidal, and antiviral activities
- GC52468 Benanomicin B A microbial metabolite with antifungal, fungicidal, and antiviral activities
- GC49040 Benanomicin B (formate) A microbial metabolite with antifungal, fungicidal, and antiviral activities
- GC33989 beta-L-D4A beta-L-D4A is a nucleoside HIV-1 reverse transcriptase inhibitor.
- GC48446 Betulin 3,28-diacetate A triterpene with antiviral and hepatoprotective activities
- GC10480 Betulinic acid A plant triterpenoid similar to bile acids
- GC35508 Bevirimat An inhibitor of HIV-1 virion maturation
- GC35510 BI 224436 BI 224436 is a novel HIV-1 noncatalytic site integrase inhibitor with EC50 values of less than 15 nM against different HIV-1 laboratory strains.
- GC32060 Bictegravir (GS-9883) Bictegravir (GS-9883) (GS-9883) is a potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM.
- GC12426 Birinapant (TL32711) An antagonist of cIAP1, cIAP2, and XIAP
- GC10263 BMS-378806 (BMS-806) BMS-378806 (BMS-806) is a potent HIV-1 attachment inhibitor that interferes with CD4-gp120 interactions.
- GC10570 BMS-538203 HIV integrase inhibitor,highly efficient
- GC10794 BMS-626529 An HIV-1 attachment inhibitor
- GC13119 BMS-663068
- GC11923 BMS-707035
- GC42967 Boromycin Boromycin is a boron-containing macrolide antibiotic that has been found in Streptomyces.
- GC38742 BRD-6929 An HDAC1 and HDAC2 inhibitor
- GC39238 BRD-K98645985 BRD-K98645985 is a BAF (mammalian SWI/SNF) transcriptional repression inhibitor with an EC50 of ~2.37 ?M.
- GC39739 Bz-RS-iSer(3-Ph)-OMe Bz-RS-iSer(3-Ph)-OMe (compound 2), a Taxol derivative, inhibits HSV replication cycle at low cytotoxicity, blocks mitotic divisions of Vero cells, influences M-MSV induced tumor size and affects immune response by inhibiting PHA-induced T lymphocyte proliferation.
- GC43031 C16 Galactosylceramide (d18:1/16:0) C16 Galactosylceramide is a glycosphingolipid that contains a galactose moiety attached to a ceramide acylated with palmitic acid .
- GC68449 CA inhibitor 1
- GC66051 Cabotegravir sodium Cabotegravir (GSK-1265744) sodium is a orally active and long-acting HIV integrase inhibitor and organic anion transporter 1/3 (OAT1/OAT3) inhibitor with IC50 values of 2.5 nM, 0.41 μM and 0.81 μM for HIVADA, OAT3 and OAT1, respectively. Cabotegravir sodium is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral drugs (ARVs). Cabotegravir sodium can be used to research AIDS.
- GC32367 CCR5 antagonist 1 CCR5 antagonist 1 is a CCR5 antagonist which can inhibit HIV replication extracted from WO 2004054974 A2.
- GC12871 CDK9 inhibitor
- GC32191 Celgosivir (MBI 3253) Celgosivir (MBI 3253) (MBI 3253; MDL 28574; MX3253) is an α-glucosidase I inhibitor; inhibits bovine viral diarrhoea virus (BVDV) with an IC50 of 1.27 μM in in vitro assay.
- GC32074 Celgosivir hydrochloride (MBI 3253 (hydrochloride)) Celgosivir hydrochloride (MBI 3253 (hydrochloride)) (MBI 3253 hydrochloride; MDL 28574 hydrochloride; MX3253 hydrochloride) is an α-glucosidase I inhibitor; inhibits bovine viral diarrhoea virus (BVDV) with an IC50 of 1.27 μM in in vitro assay.
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GC19101
Cenicriviroc
Cenicriviroc (CVC) is an oral, dual CCR2/CCR5 antagonist with nanomolar potency against both receptors.
- GC35650 Cenicriviroc Mesylate Cenicriviroc Mesylate (TAK-652 Mesylate) is a dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2, and displays potent anti-inflammatory and antiinfective activity.
- GC64261 Censavudine Censavudine (OBP-601; BMS-986001), a nucleoside analog, is a nucleoside reverse transcriptase inhibitor.
- GN10113 Cepharanthine
- GC60700 Chloroquine D5 Chloroquine D5 is deuterium labeled Chloroquine.
- GC10295 Chloroquine diphosphate Chloroquine diphosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis.
- GC43259 Cholesteryl Homo-γ-Linolenate Cholesteryl homo-γ-linolenate is a cholesterol ester.
- GC66467 Claficapavir Claficapavir (A1752) is a specific nucleocapsid protein (NC) inhibitor with an IC50 around 1 μM. Claficapavir strongly binds the HIV-1 NC (Kd=20 nM) thereby inhibiting the chaperone properties of NC and leading to good antiviral activity against the HIV-1.