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Home >> Signaling Pathways >> Microbiology & Virology >> SARS-CoV

SARS-CoV

SARS-CoV (severe acute respiratory syndrome-cornavirus) is an enveloped positive-sense single-stranded RNA viruse that transmitted from human to human.

Products for  SARS-CoV

  1. Cat.No. Product Name Information
  2. GC40559 (±)-Alliin Alliin is a cysteine sulfoxide constituent of garlic that is converted by alliinase to allicin, which imparts its pungent aroma and flavor. (±)-Alliin Chemical Structure
  3. GC40560 (+)-Alliin Alliin is a cysteine sulfoxide constituent of garlic that is converted by alliinase to allicin, which imparts its pungent aroma and flavor. (+)-Alliin Chemical Structure
  4. GC39317 (S)-Tenofovir (S)-Tenofovir ((S)-GS 1278) is the less active S-enantiomer of Tenofovir. (S)-Tenofovir Chemical Structure
  5. GC61674 2-Hydroxyacetophenone 2-Hydroxyacetophenone is a principal root volatile of the Carissa edulis. 2-Hydroxyacetophenone Chemical Structure
  6. GC61753 2-Hydroxycinnamic acid 2-Hydroxycinnamic acid is isolated from the methanol extract of Cinnamomum cassia. 2-Hydroxycinnamic acid Chemical Structure
  7. GC35144 4'-O-Methylbavachalcone 4'-O-Methylbavachalcone is a chalcone isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity, with an IC50 of 10.1 μM. 4'-O-Methylbavachalcone Chemical Structure
  8. GC62354 Acriflavine hydrochloride Acriflavine hydrochloride (Acriflavinium chloride hydrochloride) is a fluorescent acridine dye that can be used to label nucleic acid. Acriflavine hydrochloride Chemical Structure
  9. GC60051 Anti-MERS-2E6 mAb Anti-MERS-2E6 mAb (MERS-2E6; MERS Antibody-2E6), a human neutralizing antibody IgG1 (CHO expressed) that can compete for the binding of the virus Spike protein to the receptor (CD26), thereby inhibiting virus invasion into host cells. Anti-MERS-2E6 mAb Chemical Structure
  10. GC60052 Anti-MERS-3A1 mAb Anti-MERS-3A1 mAb (MERS-3A1) is a human monoclonal IgG1 antibody with the high binding affinity produced in CHO cells. Anti-MERS-3A1 mAb Chemical Structure
  11. GC66241 Anti-MERS-D12 mAb Anti-MERS-D12 mAb (MERS-D12; MERS Antibody-D12) is a human monoclonal IgG1. Anti-MERS-D12 mAb binds directly to the DPP4 interacting region of the MERS-CoV Spike receptor binding domain (RBD) and effect neutralization by directly blocking receptor binding. Anti-MERS-D12 mAb Chemical Structure
  12. GC60054 Anti-SARS-80R mAb Anti-SARS-80R mAb (SARS-80R) is a human monoclonal IgG1 antibody produced in CHO cells. Anti-SARS-80R mAb Chemical Structure
  13. GC60055 Anti-SARS-CoV-2 Spike mAb (CR3022) Anti-SARS-CoV-2 Spike mAb (CR3022) is a a CHO cell derived human monoclonal IgG1 antibody. Anti-SARS-CoV-2 Spike mAb (CR3022) Chemical Structure
  14. GC60056 Anti-Spike-RBD mAb Anti-Spike-RBD mAb is a CHO cell derived human monoclonal IgG1 antibody. Anti-Spike-RBD mAb Chemical Structure
  15. GC60057 Anti-Spike-RBD Single Domain mAb Anti-Spike-RBD Single Domain mAb is a CHO cell derived Alpaca monoclonal VHH-huFc antibody, specifically binds to SARS-CoV-2 RBD with high affinity. Anti-Spike-RBD Single Domain mAb Chemical Structure
  16. GC67913 Antiviral agent 5 Antiviral agent 5 Chemical Structure
  17. GC62320 AT-511 AT-511 (AT-511) is a potent and orally active HCV viral replication inhibitor. AT-511 Chemical Structure
  18. GC62321 AT-527

    AT-527(Bemnifosbuvir hemisulfate), a hemisulfate salt of AT-511, a guanosine nucleotide proagent, is a potent and orally active HCV viral replication inhibitor.

     AT-527 Chemical Structure
  19. GC63412 AT-9010 tetrasodium

    AT-9010 tetrasodium, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication).

     AT-9010 tetrasodium Chemical Structure
  20. GC17903 Atovaquone unique naphthoquinone with broad-spectrum antiprotozoal activity Atovaquone Chemical Structure
  21. GC65180 ATV006 ATV006 is a potent, orally active antiviral agent and ester prodrugs of GS-441524. ATV006 Chemical Structure
  22. GC60609 Aviptadil acetate Aviptadil acetate is an analog vasoactive intestinal polypeptide (VIP) with potent vasodilatory effects. Aviptadil acetate Chemical Structure
  23. GC46903 Azithromycin-d3 An internal standard for the quantification of azithromycin Azithromycin-d3 Chemical Structure
  24. GC14250 Bepotastine Besilate Non-sedating, selective antagonist of histamine 1 (H1) receptor Bepotastine Besilate Chemical Structure
  25. GC10959 Boceprevir An NS3/4A protease inhibitor Boceprevir Chemical Structure
  26. GC46936 Boceprevir-d9 An internal standard for the quantification of boceprevir Boceprevir-d9 Chemical Structure
  27. GC61885 Bonducellpin D Bonducellpin D is a furanoditerpenoid lactone isolated from Caesalpinia minax. Bonducellpin D Chemical Structure
  28. GC15089 Carfilzomib (PR-171) A proteasome inhibitor Carfilzomib (PR-171) Chemical Structure
  29. GC63779 CCF0058981 CCF0058981 (CCF981), 3-chlorophenyl analogue, is a noncovalent SARS-CoV-2 3CLpro (SC2) inhibitor with an IC50 of 68 nM. CCF0058981 Chemical Structure
  30. GC31707 Chebulagic acid Chebulagic acid is a COX-LOX dual inhibitor isolated from the fruits of Terminalia chebula Retz, on angiogenesis. Chebulagic acid Chemical Structure
  31. GC19549 Chloroquine

    An autophagy and toll-like receptors (TLRs) inhibitor

     Chloroquine Chemical Structure
  32. GC60700 Chloroquine D5 Chloroquine D5 is deuterium labeled Chloroquine. Chloroquine D5 Chemical Structure
  33. GC10295 Chloroquine diphosphate Chloroquine diphosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine diphosphate Chemical Structure
  34. GC45885 Chloroquine-d5 (phosphate) An internal standard for the quantification of chloroquine Chloroquine-d5 (phosphate) Chemical Structure
  35. GC64289 Cichoriin Cichoriin is an active compounds against SARS-CoV-2, and may be a potential candidate in treating severe COVID-19. Cichoriin Chemical Structure
  36. GC64264 Cleistanthin B Cleistanthin B (Diphyllin O-glucoside) is an orally active arylnaphthalene lignan lactone glycoside. Cleistanthin B Chemical Structure
  37. GC12635 Clevudine antiviral drug Clevudine Chemical Structure
  38. GC12879 Danoprevir (RG7227) An HCV NS3/4A protease inhibitor Danoprevir (RG7227) Chemical Structure
  39. GC17942 Darunavir Ethanolate nonpeptidic HIV protease inhibitor Darunavir Ethanolate Chemical Structure
  40. GC12828 Daunorubicin

    DNA topoisomerase II inhibitor

     Daunorubicin Chemical Structure
  41. GC61677 Direct Violet 1 Direct Violet 1, an azo dye, is a textile dye. Direct Violet 1 Chemical Structure
  42. GC18620 EIDD-1931

    A ribonucleoside analog with antiviral activity

     EIDD-1931 Chemical Structure
  43. GC18413 EIDD-2801

    An orally bioavailable prodrug of the ribonucleoside analog EIDD-1931

     EIDD-2801 Chemical Structure
  44. GC64368 Ensitrelvir fumarate Ensitrelvir (S-217622) fumarate is the first orally active non-covalent, non-peptidic, SARS-CoV-2 3CL protease inhibitor (IC50=13 nM). Ensitrelvir fumarate Chemical Structure
  45. GC60856 FOY 251 FOY 251, an anti-proteolytic active metabolite Camostate, acts as a proteinase inhibitor. FOY 251 Chemical Structure
  46. GC62221 GRL-0496 GRL-0496 is a potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitor, with an IC50 of 30 nM in both enzyme inhibitory and antiviral assays. GRL-0496 Chemical Structure
  47. GC39172 GRL0617 A SARS-CoV and SARS-CoV-2 PLpro inhibitor GRL0617 Chemical Structure
  48. GC63563 GS-621763 GS-621763, an orally bioavailable prodrug of GS-441524, shows antiviral activity against SARS-CoV-2 pathogenesis in mice. GS-621763 Chemical Structure
  49. GC62414 HCoV-229E-IN-1 HCoV-229E-IN-1 is a potent inhibitor of HCoV-229E replication, with an EC50 of 0.65 μM and 0.6 μM in MTS and CPE cells, respectively. HCoV-229E-IN-1 Chemical Structure
  50. GC63500 HeE1-2Tyr HeE1-2Tyr, a pyridobenzothiazole compound, is a flavivirus RNA dependent RNA polymerases (RdRp) inhibitor. HeE1-2Tyr Chemical Structure
  51. GC12544 Hydroxychloroquine Sulfate

    Autophagy inhibitor

     Hydroxychloroquine Sulfate Chemical Structure
  52. GC47445 Hydroxychloroquine-d4 (sulfate) An internal standard for the quantification of hydroxychloroquine Hydroxychloroquine-d4 (sulfate) Chemical Structure
  53. GC60930 Imatinib D4 Imatinib D4 (STI571 D4) is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib D4 Chemical Structure
  54. GC39612 Imatinib D8 Imatinib D8 (STI571 D8) is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib D8 Chemical Structure
  55. GC43925 Ivermectin B1b Ivermectin B1b is the minor component. Ivermectin B1b Chemical Structure
  56. GC66366 Kansuinine B Kansuinine B inhibits IL-6-induced Stat3 activation. Kansuinine B possesses anti-viral activity and could be used in the study for COVID-19. Kansuinine B Chemical Structure
  57. GC64263 Kobophenol A Kobophenol A, an oligomeric stilbene, blocks the interaction between the ACE2 receptor and S1-RBD with an IC50 of 1.81 μM and inhibits SARS-CoV-2 viral infection in cells with an EC50 of 71.6 μM. Kobophenol A Chemical Structure
  58. GC62667 KW-8232 KW-8232, an orally active anti-osteoporotic agent, and can reduces the biosynthesis of PGE2. KW-8232 Chemical Structure
  59. GC10317 Lamivudine Nucleoside analog reverse transcriptase inhibitor Lamivudine Chemical Structure
  60. GC17439 Ledipasvir An HCV NS5A inhibitor Ledipasvir Chemical Structure
  61. GC69367 Lenzilumab

    Lenzilumab (KB 003) is a humanized monoclonal antibody that targets CSF2/GM-CSF and can be used in research for COVID-19, chronic myelomonocytic leukemia (CMML), and juvenile myelomonocytic leukemia (JMML).

     Lenzilumab Chemical Structure
  62. GC13716 Lopinavir A potent HIV-1 protease inhibitor Lopinavir Chemical Structure
  63. GC47573 Lopinavir-d8 An internal standard for the quantification of lopinavir Lopinavir-d8 Chemical Structure
  64. GC63065 Merafloxacin Merafloxacin (CI-934), a fluoroquinolone antibacterial agent, is a selective programmed -1 ribosomal frameshifting (-1 PRF) inhibitor of beta coronaviruses. Merafloxacin Chemical Structure
  65. GC63790 MERS-CoV-IN-1 MERS-CoV-IN-1 exhibits excellent inhibitory activity against coronavirus. MERS-CoV-IN-1 Chemical Structure
  66. GC14363 Mitoxantrone HCl Mitoxantrone HCl is a potent topoisomerase II inhibitor. Mitoxantrone HCl Chemical Structure
  67. GC12301 Mizoribine DNA/RNA synthesis inhibitor Mizoribine Chemical Structure
  68. GC39497 ML188 ML188, a first in class probe, is a selective non-covalent SARS-CoV 3CLpro inhibitor with an IC50 of 1.5 μM. ML188 Chemical Structure
  69. GC11655 Moexipril HCl Moexipril HCl (RS-10085) is an orally active inhibitor of angiotensin-converting enzyme (ACE), and becomes effective by being hydrolyzed to moexiprila (hydrochloride). Moexipril HCl Chemical Structure
  70. GC62162 Molnupiravir Molnupiravir (EIDD-2801) is an orally bioavailable prodrug of the ribonucleoside analog EIDD-1931. Molnupiravir Chemical Structure
  71. GC67754 Molnupiravir-d7 Molnupiravir-d7 Chemical Structure
  72. GC50727 MPro 13b MPro 13b is a potent Mpro inhibitor. MPro 13b Chemical Structure
  73. GC47707 MPro Inhibitor 11a An inhibitor of SARS-CoV-2 Mpro MPro Inhibitor 11a Chemical Structure
  74. GC47708 MPro Inhibitor 11b MPro Inhibitor 11b is a SARS-CoV-2 3CLpro covalent inhibitor, with an IC50 of 40 nM. MPro Inhibitor 11b Chemical Structure
  75. GC62208 Mpro inhibitor N3 hemihydrate Mpro inhibitor N3 hemihydrate is a potent inhibitor of SARS-CoV-2 Mpro with an EC50 of 16.77 μM for SARS-CoV-2. Mpro inhibitor N3 hemihydrate Chemical Structure
  76. GC50732 MPro N3 MPro N3 Chemical Structure
  77. GC69538 Narsoplimab

    Narsoplimab (OMS 721) is a high-affinity fully human immunoglobulin G4 (IgG4) monoclonal antibody that binds to MASP-2 and blocks lectin pathway activation. Narsoplimab can be used in hematopoietic stem cell transplantation and research on SARS-CoV-2.

     Narsoplimab Chemical Structure
  78. GC17709 Nelfinavir HIV-1 protease inhibitor Nelfinavir Chemical Structure
  79. GC61956 NHC-diphosphate NHC-diphosphate is an active phosphorylated?intracellular metabolite?of β-d-N4-Hydroxycytidine (NHC) as a diphosphate form. NHC-diphosphate Chemical Structure
  80. GC61130 NHC-triphosphate

    NHC-triphosphate is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a triphosphate form.

     NHC-triphosphate Chemical Structure
  81. GC61158 ONO-5334 ONO-5334 is a potent, selective and orally active cathepsin K inhibitor with Ki values of 0.10 nM, 0.049 nM and 0.85 nM for human, rabbit and rat cathepsin K, respectively. ONO-5334 Chemical Structure
  82. GC62133 PF-00835231 PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively. PF-00835231 Chemical Structure
  83. GC62692 PF-07304814 PF-07304814 (PF-07304814), a phosphate prodrug of PF-00835231, acts as a potent 3CLproprotease (Mpro) inhibitor with SARS-CoV-2 antiviral activity. PF-07304814 Chemical Structure
  84. GC62631 PF-07321332 PF-07321332 (PF-07321332) is a potent and orally active SARS-CoV3C-like protease (3CLPRO) inhibitor. PF-07321332 Chemical Structure
  85. GC12116 Pitavastatin Calcium Enzyme HMGCR inhibitor Pitavastatin Calcium Chemical Structure
  86. GC36939 PLpro inhibitor PLpro inhibitor is a potent inhibitor of papain-like protease (PLpro) with an IC50 of 2.6 ?M. PLpro inhibitor Chemical Structure
  87. GC13197 Praziquantel anthelmintic Praziquantel Chemical Structure
  88. GC37020 Prulifloxacin A prodrug from of ulifloxacin Prulifloxacin Chemical Structure
  89. GC63782 RdRP-IN-2 RdRP-IN-2 is a RNA dependent RNA polymerase (RdRp) inhibitor. RdRP-IN-2 Chemical Structure
  90. GC62639 rel-Zotatifin rel-Zotatifin is the racemic isomer of Zotatifin, acts as an eIF4A?inhibitor with activity less than Zotatifin. rel-Zotatifin Chemical Structure
  91. GC32223 Remdesivir (GS-5734) Remdesivir (GS-5734) (GS-5734), a nucleoside analogue with effective antiviral activity, has EC50s of 3.3 μM, 4.7 μM, 32 μM, 3.7 μM and 9.2 μM for SARS-CoV-2 and its variants alpha, beta, gamma and delta, respectively. Remdesivir (GS-5734) Chemical Structure
  92. GC25863 Riamilovir Riamilovir (Triazavirin) is a broad-spectrum antiviral drug candidate, which can be used for potential application against the Coronavirus 2019-nCoV. Riamilovir Chemical Structure
  93. GC17303 Ritonavir An HIV protease inhibitor Ritonavir Chemical Structure
  94. GC64331 Ritonavir-13C,d3 Ritonavir-13C,d3 Chemical Structure
  95. GC16359 Rosuvastatin Competitive inhibitor of HMG-CoA reductase Rosuvastatin Chemical Structure
  96. GC15736 Rosuvastatin Calcium HMG-CoA reductase inhibitor Rosuvastatin Calcium Chemical Structure
  97. GC65943 SARS-CoV-2 3CLpro-IN-2 SARS-CoV-2 3CLpro-IN-2 (Compound 1) is a potent inhibitor of 3CL protease. SARS-CoV-2 3CLpro-IN-2 has the potential for the research of SARS-CoV-2 diseases. SARS-CoV-2 3CLpro-IN-2 Chemical Structure
  98. GC69861 SARS-CoV-2 nsp13-IN-1

    SARS-CoV-2 nsp13-IN-1 (compound C1) is an effective inhibitor of nsp13 (non-structural protein 13). SARS-CoV-2 nsp13-IN-1 only inhibits the ssDNA+ ATPase activity of nsp13, with an IC50 of 6 μM. It does not inhibit ssDNA- ATPase activity. SARS-CoV-2 nsp13-IN-1 can be used for COVID-19 research.

     SARS-CoV-2 nsp13-IN-1 Chemical Structure
  99. GC67793 SARS-CoV-2-IN-13 SARS-CoV-2-IN-13 Chemical Structure
  100. GC69860 SARS-CoV-2-IN-14

    SARS-CoV-2-IN-14 (compound 6) is an effective inhibitor of SARS-CoV-2 with an IC50 of 0.39 μM. It is a chloronitroaniline analog. SARS-CoV-2-IN-14 has higher stability in human plasma and liver S9 enzyme assays compared to chloronitroaniline, and oral administration can improve its bioavailability and half-life.

     SARS-CoV-2-IN-14 Chemical Structure
  101. GC64011 SARS-CoV-2-IN-6 SARS-CoV-2-IN-6 is a SARS-CoV-2 3CLpro inhibitor that shows the most potent enzyme inhibitory IC50 value of 73 nM. SARS-CoV-2-IN-6 Chemical Structure

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