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Roxatidine Acetate HCl (Synonyms: HOE 760, TZU-0460)

Catalog No.GC10369

Roxatidine Acetate HCl is a potent, selective, competitive and orally active histamine H2-receptor antagonist.

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Roxatidine Acetate HCl Chemical Structure

Cas No.: 93793-83-0

Size Price Stock Qty
10mM (in 1mL DMSO)
$34.00
In stock
50mg
$48.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Roxatidine Acetate Hydrochloride is a specific and competitive histamin H2 receptor antagonist.Target: Histamin H2 ReceptorRoxatidine Acetate Hydrochloride is a histamine H2-receptor antagonist which, after almost complete oral absorption (greater than 95%), is rapidly converted to its active metabolite, roxatidine, by esterases in the small intestine, plasma and liver. Roxatidine Acetate Hydrochloride is a potent inhibitor of basal and stimulated gastric acid secretion in animals and humans and, like most other H2-receptor antagonists, has no anti-androgenic effects and does not interfere with the hepatic metabolism of other drugs [1, 2].

References:
[1]. Murdoch, D. and D. McTavish, Roxatidine acetate. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic potential in peptic ulcer disease and related disorders. Drugs, 1991. 42(2): p. 240-60.
[2]. Pali-Scholl, I. and E. Jensen-Jarolim, Anti-acid medication as a risk factor for food allergy. Allergy, 2011. 66(4): p. 469-77.

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