Home>>Sphingosine-1-Phosphate Lyase Fluorogenic Substrate

Sphingosine-1-Phosphate Lyase Fluorogenic Substrate (Synonyms: RBM13, S1P Lyase Fluorogenic Substrate)

Catalog No.GC44936

S1P lyase fluorogenic substrate is a substrate of S1P lyase, leading to the production of the fluorescent product umbelliferone (7-hydroxycoumarin) under appropriate conditions.

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Sphingosine-1-Phosphate Lyase Fluorogenic Substrate Chemical Structure

Size Price Stock Qty
1mg
$494.00
In stock
5mg Please Inquire Please Inquire
10mg
$3,947.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

S1P lyase fluorogenic substrate is a substrate of S1P lyase, leading to the production of the fluorescent product umbelliferone (7-hydroxycoumarin) under appropriate conditions. This compound is intended to be used to monitor or measure S1P lyase activity.

Chemical Properties

Cas No. SDF
Synonyms RBM13, S1P Lyase Fluorogenic Substrate
Canonical SMILES O=C1OC2=C(C=CC(OCC[C@@H](O)[C@@H]([NH3+])COP([O-])(O)=O)=C2)C=C1
Formula C14H18NO8P M.Wt 359.3
Solubility 10 Mm NaOH: 1 mg/ml,DMF: .5 mg/ml,DMSO: .5 mg/ml,PBS (pH 7.2): 10 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 2.7832 mL 13.9159 mL 27.8319 mL
5 mM 0.5566 mL 2.7832 mL 5.5664 mL
10 mM 0.2783 mL 1.3916 mL 2.7832 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Reviews

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Average Rating: 5 ★★★★★ (Based on Reviews and 13 reference(s) in Google Scholar.)

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