Z-YVAD-AFC (trifluoroacetate salt) (Synonyms: Z-Tyr-Val-Ala-Asp-AFC, Z-Tyr-Val-Ala-Asp-7-amino-4-trifluoromethylcoumarin, Z-YVAD-7-amino-4-trifluoromethylcoumarin) |
Catalog No.GC40153 |
Z-YVAD-AFC is a fluorogenic substrate for caspase-1.
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Sample solution is provided at 25 µL, 10mM.
Z-YVAD-AFC is a fluorogenic substrate for caspase-1. Upon enzymatic cleavage by caspase-1, 7-amino-4-trifluoromethylcoumarin (AFC) is released and its fluorescence can be used to quantify caspase-1 activity. AFC displays excitation/emission maxima of 400/505 nm, respectively.
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