Home>>Signaling Pathways>> Chromatin/Epigenetics>> JAK>>1,2,3,4,5,6-Hexabromocyclohexane

1,2,3,4,5,6-Hexabromocyclohexane

Catalog No.GC17055

Potently and directly inhibits JAK2 tyrosine kinase autophosphorylation, specifically inhibiting ligand-dependent JAK2 activation.

Products are for research use only. Not for human use. We do not sell to patients.

1,2,3,4,5,6-Hexabromocyclohexane Chemical Structure

Cas No.: 1837-91-8

Size Price Stock Qty
10mM (in 1mL DMSO)
$34.00
In stock
50mg
$74.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

Potently and directly inhibits JAK2 tyrosine kinase autophosphorylation, specifically inhibiting ligand-dependent JAK2 activation. A 16-hour treatment with 1 μM of compound reduces JAK2 tyrosine autophosphorylation levels to ~ 50% while 50 μM elimates nearly all JAK2 activity. Non-cytotoxic at 100 μM.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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